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Thyroid Embryogenesis

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Thyroid Diseases in Childhood

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Abstract

The thyroid gland is mainly composed of highly specialized epithelial cells, known as thyroid follicular cells, assembled in a peculiar histological organization characterized by the presence of follicles. In this chapter, we summarize what is known of the processes regulating the differentiation of thyroid cells and the morphogenesis of the gland. The use of animal models has made it possible to identify genes and mechanisms involved in normal thyroid development and are giving insights to elucidate the molecular pathology of thyroid dysgenesis.

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Authors and Affiliations

  1. Department of Molecular Medicine and Medical Biotechnologies, Federico II University, Via Pansini, Naples, 80131, Italy

    Mario De Felice & Roberto Di Lauro

  2. Institute for Experimental Endocrinology and Oncology (IEOS), CNR, Naples, Italy

    Mario De Felice

Authors
  1. Mario De Felice
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  2. Roberto Di Lauro
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Corresponding author

Correspondence to Roberto Di Lauro .

Editor information

Editors and Affiliations

  1. Novara, Italy

    Gianni Bona

  2. Messina, Italy

    Filippo De Luca

  3. Division of Pediatrics, Piedemonte Hospital, Novara, Italy

    Alice Monzani

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De Felice, M., Di Lauro, R. (2015). Thyroid Embryogenesis. In: Bona, G., De Luca, F., Monzani, A. (eds) Thyroid Diseases in Childhood. Springer, Cham. https://doi.org/10.1007/978-3-319-19213-0_1

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  • DOI: https://doi.org/10.1007/978-3-319-19213-0_1

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-19212-3

  • Online ISBN: 978-3-319-19213-0

  • eBook Packages: MedicineMedicine (R0)

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