Abstract
Proteins are macromolecules that facilitate virtually every biological process. Information on functional and structural characteristics of proteins is invaluable in life sciences, but remain difficult to obtain, both computationally and experimentally.
In recent work, we have introduced a novel method for functional characterization, which we refer to as protein energy profiling. The eProS (energy profile suite) is an online knowledgebase, toolbox and database that provides a webspace for protein energy profile analyses to the scientific community. The objective of eProS is to offer a free-for-all repository of energy profile data, annotations, visualizations, as well as tools that can aid in deducing relations complementing and supporting findings made by traditional bioinformatics methods.
In this paper, we discuss the underlying biological and theoretical backgrounds used by implemented methods and tools, and also introduce recent enhancements and developments.
eProS is available at http://bioservices.hs-mittweida.de/Epros.
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Heinke, F., Stockmann, D., Schildbach, S., Langer, M., Labudde, D. (2015). eProS – A Bioinformatics Knowledgebase, Toolbox and Database for Characterizing Protein Function. In: Kozielski, S., Mrozek, D., Kasprowski, P., Małysiak-Mrozek, B., Kostrzewa, D. (eds) Beyond Databases, Architectures and Structures. BDAS 2015. Communications in Computer and Information Science, vol 521. Springer, Cham. https://doi.org/10.1007/978-3-319-18422-7_51
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DOI: https://doi.org/10.1007/978-3-319-18422-7_51
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