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Pathogenesis of psoriasis and psoriatic arthritis

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Handbook of Psoriasis and Psoriatic Arthritis

Abstract

The pathophysiology of psoriasis is multifaceted and dynamic, involving a complex interplay between constitutive cells of the skin and the innate and adaptive immune systems. Until the early 1980s, psoriasis was considered to be primarily a disease of epidermal keratinocyte proliferation, with the cutaneous inflammatory infiltrate a secondary consequence.

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Authors and Affiliations

  1. The University of Manchester, Manchester, UK

    Laura Coates, Laura Savage & Paul Emery

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  1. Laura Coates
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  2. Laura Savage
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  1. Manchester, United Kingdom

    Richard Warren

  2. Montreal, Québec, Canada

    Alan Menter

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Coates, L., Savage, L., Emery, P. (2016). Pathogenesis of psoriasis and psoriatic arthritis. In: Warren, R., Menter, A. (eds) Handbook of Psoriasis and Psoriatic Arthritis. Adis, Cham. https://doi.org/10.1007/978-3-319-18227-8_2

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  • DOI: https://doi.org/10.1007/978-3-319-18227-8_2

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