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Infants of Diabetic Mothers

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Neonatology

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Abstract

While advances in maternal and neonatal medical care continue to improve the outcomes for infants born to mothers with glucose intolerance during pregnancy, the risks for spontaneous abortion, stillbirth, congenital malformations, and perinatal mortality and morbidity still exist. Abnormal maternal glycemic control caused by gestational diabetes mellitus (GDM) or pregestational diabetes mellitus complicate up to 10 % of pregnancies, and as the significantly overweight pediatric population develops into their child-bearing years, this number is likely to rise Nold and Georgieff (Pediatr Clin N Am 51: 619–637, 2004). Pregnancies of mothers with diabetes are given increased surveillance, as the multifaceted metabolic changes that occur in the mother can place the infant at risk for periconceptional, fetal, neonatal, and long-term morbidities Nold and Georgieff (Pediatr Clin N Am 51: 619–637, 2004); Widness (Fetal risks and neonatal complications of diabetes mellitus and metabolic and endocrine disorders. In: Brody SA, Ueland K (eds) Endocrine disorders in pregnancy. Appleton-Lang, Norwalk, CT, pp 273–297, 1989). Fortunately, appropriate periconceptional and prenatal care can improve the risks of perinatal complications by close monitoring of maternal glycemic control.

This work was sponsored in part by grants to MKG from the National Institutes of Health (HD-29421; NS-34458; HD-54490; and RR-00400-39).

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Authors and Affiliations

  1. Division of Neonatology, Department of Pediatrics Center for Neurobehavioral Development, University of Minnesota, Minneapolis, MN, USA

    Erin A. Osterholm & Michael K. Georgieff

  2. Children’s Hospitals and Clinics of Minnesota, Minneapolis, MN, USA

    Jane E. Barthell

Authors
  1. Erin A. Osterholm
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  2. Jane E. Barthell
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  3. Michael K. Georgieff
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Correspondence to Michael K. Georgieff .

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Editors and Affiliations

  1. Siena, Italy

    Giuseppe Buonocore

  2. Medicina della Riproduzione, Università di Siena Dipto. Pediatria, Ostetricia e, Siena, Italy

    Rodolfo Bracci

  3. Liverpool Women's Hospital Neonatal Unit, Liverpool, United Kingdom

    Michael Weindling

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Osterholm, E.A., Barthell, J.E., Georgieff, M.K. (2016). Infants of Diabetic Mothers. In: Buonocore, G., Bracci, R., Weindling, M. (eds) Neonatology. Springer, Cham. https://doi.org/10.1007/978-3-319-18159-2_195-1

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  • DOI: https://doi.org/10.1007/978-3-319-18159-2_195-1

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