Clinical Symptoms

Abstract

Acrodermatitis Enteropathica symptoms usually begin to appear either within the first few days of life in formula fed infants or immediately upon discontinuation of breastfeeding [1]. Appearance of symptoms after change from breast milk to bovine milk indicates that human milk has a protective role which may be due to presence of low molecular binding agents that increase zinc bioavailability [2]. Common early symptoms of AE include the appearance of perleche (angular chelitis), skin lesions, erythematous patches, plaques of dry and scaly skin, and eczematous plaques on the face, scalp, and genital area: these skin dermatitises deteriorate quickly [1]. The lesions gradually begin emerging inside the mouth and then on the hands and feet, accompanied by Paronychia and inflammatory dermatitis on the palms, wrinkles on fingers, as well as scaly skin on the neck [3]. Next, diarrhea is one of the most variable symptoms of AE. If it appears and is exacerbated, it could lead to dehydration and loss of essential minerals and electrolytes; which could result in complications with the clinical treatment [1].