Abstract
Prone positioning usually improves oxygenation and has been used as a rescue therapy for severe hypoxemia in patients with acute respiratory distress syndrome. Moreover, prone positioning might prevent ventilator induced lung injury, by reducing lung stress and atalectrauma.
One multicenter randomized controlled trail (PROSEVA) recently showed, for the first time, a significant decrease in mortality rates with daily prone positioning sessions of at least 16 hours in patients with early severe acute respiratory distress syndrome (defined as PaO2/FiO2 < 150 mmHg). However, prone positioning requires high experience and specifically trained personnel, and its optimal daily duration is unknown.
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Pisano, A., Verniero, L., Masserini, F. (2015). Prone Positioning to Reduce Mortality in Acute Respiratory Distress Syndrome. In: Landoni, G., Mucchetti, M., Zangrillo, A., Bellomo, R. (eds) Reducing Mortality in Critically Ill Patients. Springer, Cham. https://doi.org/10.1007/978-3-319-17515-7_4
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DOI: https://doi.org/10.1007/978-3-319-17515-7_4
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