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High-Frequency Oscillatory Ventilation

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Reducing Mortality in Critically Ill Patients

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Abstract

High frequency oscillatory ventilation is characterized by very low tidal volumes, often smaller than anatomic death space, and high respiratory frequencies (3–15 Hz). This strategy was thought to reduce ventilator induced lung injury, avoiding volutrauma and barotrauma. According to most recent data, high frequency oscillatory ventilation does not offer any real advantage when compared to current protective lung ventilation. Moreover it is associated with an increased need for sedative and neuromuscular blocker drugs, unstable hemodynamics and lung barotrauma. The OSCILLATE trial demonstrated an increased risk of death in patients undergoing high frequency oscillatory ventilation. Therefore, high frequency oscillatory ventilation should be avoided as a first-line treatment in patients with acute respiratory distress syndrome.

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Authors and Affiliations

  1. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy

    Laura Pasin MD & Alessandro Belletti MD

  2. Faculty of Medical Sciences, Vita-Salute San Raffaele University, Milan, Italy

    Pasquale Nardelli

Authors
  1. Laura Pasin MD
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  2. Pasquale Nardelli
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  3. Alessandro Belletti MD
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Corresponding author

Correspondence to Laura Pasin MD .

Editor information

Editors and Affiliations

  1. Department of Anesthesia and Intensive care, IRCCS San Raffaele Scientifi c Institute, Milan, Milano, Italy

    Giovanni Landoni

  2. Department of Anesthesia and Intensive care, IRCCS San Raffaele Scientific Institute, Milan, Milano, Italy

    Marta Mucchetti

  3. San Raffaele Hospital, Milan, Italy

    Alberto Zangrillo

  4. Department of Intensive Care, Austin Hospital, Heidelberg, Vic. 3084, Australia

    Rinaldo Bellomo

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Pasin, L., Nardelli, P., Belletti, A. (2015). High-Frequency Oscillatory Ventilation. In: Landoni, G., Mucchetti, M., Zangrillo, A., Bellomo, R. (eds) Reducing Mortality in Critically Ill Patients. Springer, Cham. https://doi.org/10.1007/978-3-319-17515-7_14

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  • DOI: https://doi.org/10.1007/978-3-319-17515-7_14

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17514-0

  • Online ISBN: 978-3-319-17515-7

  • eBook Packages: MedicineMedicine (R0)

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