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Cystic Fibrosis

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Textbook of Pediatric Gastroenterology, Hepatology and Nutrition

Abstract

The cystic fibrosis transmembrane regulator protein (CFTR) is a chloride and bicarbonate channel situated at the apical surface of secretory membranes. Cystic fibrosis (CF) results from a dysfunction of this ion channel. CFTR dysfunction affects the pancreas, hepatobiliary system, and the intestinal tract. This chapter describes the gastrointestinal and nutritional manifestations of CF with current medical management.

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Authors and Affiliations

  1. Pediatric Gastroenterology Unit, Hadassah Hebrew University Medical Center, 91240, Jerusalem, Israel

    Michael Wilschanski

  2. Stead Family Department of Pediatrics, University of Iowa Children’s Hospital, 2865 JPP Pediatrics, 200 Hawkins Drive, 52242, Iowa City, IA, USA

    Aliye Uc

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  1. Michael Wilschanski
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  2. Aliye Uc
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Correspondence to Michael Wilschanski .

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Editors and Affiliations

  1. Department of Pediatrics, University of Chicago, Chicago, Illinois, USA

    Stefano Guandalini

  2. Clinical Director Child Health King’s College Hospital, Professor and Director Pediatric Liver, GI and Nutrition Center, London, United Kingdom

    Anil Dhawan

  3. Department of Pediatrics, Hebrew University Hadassah Hospital, Jerusalem, Israel

    David Branski

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© 2016 Springer International Publishing Switzerland

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Wilschanski, M., Uc, A. (2016). Cystic Fibrosis. In: Guandalini, S., Dhawan, A., Branski, D. (eds) Textbook of Pediatric Gastroenterology, Hepatology and Nutrition. Springer, Cham. https://doi.org/10.1007/978-3-319-17169-2_41

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  • DOI: https://doi.org/10.1007/978-3-319-17169-2_41

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17168-5

  • Online ISBN: 978-3-319-17169-2

  • eBook Packages: MedicineMedicine (R0)

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