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Hematopoietic Stem Cell Transplantation

  • Chapter
Survivors of Childhood and Adolescent Cancer

Part of the book series: Pediatric Oncology ((PEDIATRICO))

Abstract

Hematopoietic stem cell transplant (HSCT) is increasingly used for the treatment of both malignancies and nonmalignant diseases. This has been made possible by several factors, including expansion of the unrelated donor pool, advances in mobilization and collection of autologous cells, and reduced intensity conditioning regimens. Although transplant-related mortality and relapse remain obstacles, an increasing number of children are surviving following HSCT. Both the HSCT antecedent therapy and the posttransplant complications have multisystem effects, and understanding and anticipating these are important in caring for the children affected. This chapter will provide a brief overview, as many of these complications are discussed in more depth in other chapters of this book.

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Authors and Affiliations

  1. Division of Oncology, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Anne Wohlschlaeger & Nancy Bunin

  2. Division of Endocrinology and Oncology, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Sogol Mostoufi-Moab

Authors
  1. Anne Wohlschlaeger
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  2. Sogol Mostoufi-Moab
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  3. Nancy Bunin
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Corresponding author

Correspondence to Anne Wohlschlaeger .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, MD Anderson Cancer Center, Houston, Texas, USA

    Cindy L. Schwartz

  2. Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

    Wendy L. Hobbie

  3. Departments of Radiation Oncology and Pediatrics, University of Rochester Medical Center, James P. Wilmot Cancer Ctr, Rochester, New York, USA

    Louis S. Constine

  4. Center for Cancer And Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California, USA

    Kathleen S. Ruccione

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Wohlschlaeger, A., Mostoufi-Moab, S., Bunin, N. (2015). Hematopoietic Stem Cell Transplantation. In: Schwartz, C., Hobbie, W., Constine, L., Ruccione, K. (eds) Survivors of Childhood and Adolescent Cancer. Pediatric Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-16435-9_18

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  • DOI: https://doi.org/10.1007/978-3-319-16435-9_18

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-16434-2

  • Online ISBN: 978-3-319-16435-9

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