Abstract
The overall annual incidence of phaeochromocytoma is 6 per one million population [1]. MPCs account for only 10 % of all phaeochromocytomas and mostly occur in the 30–40-year age group. Clinically, MPCs like their benign counterparts present with paroxysmal hypertension, headaches, palpitations, etc. The suspicion of malignancy will be raised by the persistence of the signs and symptoms, as well as the elevated values of plasma and urinary methoxyamines after surgical excision of the tumour. The histopathological features of malignancy are controversial and not specific.
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Eisenhofer G, Lenders JW, Siegert G, Bornstein SR, Friberg P, Milosevic D, Mannelli M, Linehan WM, Adams K, Timmers HJ, Pacak K. Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status. Eur J Cancer. 2012;48(11):1739–49.
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Al-Mamari, S.A., Al-Busaidy, S.S. (2015). Malignant Phaeochromocytoma (MPC). In: Al-Mamari, S., Al-Busaidy, S. (eds) Urological Cancer Management. Springer, Cham. https://doi.org/10.1007/978-3-319-16301-7_28
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DOI: https://doi.org/10.1007/978-3-319-16301-7_28
Publisher Name: Springer, Cham
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