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Benign Hepatocellular Tumors

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Surgical Pathology of Liver Tumors

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Abstract

Benign hepatocellular tumors can occur both in the non-cirrhotic and cirrhotic livers. In non-cirrhotic livers, these lesions are categorized as focal nodular hyperplasia and hepatic adenoma, both of which are most commonly seen in women during reproductive age. Adenoma is less common than focal nodular hyperplasia, but differs from it by having a small risk of bleeding and malignant transformation. In the setting of cirrhosis, macroregenerative nodules are grossly distinct hepatocellular nodules that consist of benign hepatocytes similar to those of the background cirrhotic nodules. Other benign hepatocellular tumors resembling inflammatory type adenoma and focal nodular hyperplasia have also been recently described in alcoholic cirrhosis. The clinical and pathologic features of all the above-mentioned entities, along with their differential diagnoses, are discussed and illustrated in this chapter.

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  1. Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Hilton 11, 200 First St SW, Rochester, MN, 55902, USA

    Taofic Mounajjed

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  1. Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

    Taofic Mounajjed

  2. Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

    Vishal S. Chandan

  3. Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

    Michael S. Torbenson

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Mounajjed, T. (2015). Benign Hepatocellular Tumors. In: Mounajjed, T., Chandan, V., Torbenson, M. (eds) Surgical Pathology of Liver Tumors. Springer, Cham. https://doi.org/10.1007/978-3-319-16089-4_4

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