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A Dual Infrared Ray Imaging System for Sentinel Node Mapping Against Early Gastric Cancer: Absorption and Florescence Methods by Infrared Ray Laparoscopy System Combined with Indocyanine Green

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Fluorescence Imaging for Surgeons

Abstract

Evolutions in minimally invasive surgical techniques and advances in sentinel node navigation surgery (SNNS) have had considerable impact on current insights into surgical treatment of gastric cancer. The current study is a clinical exploration and feasibility study of a novel detection system for sentinel biopsy using a new dual imaging system in absorption and florescence methods by infrared ray electronic endoscopy combined with indocyanine green (ICG). Sentinel node (SN) biopsy using ICG was performed in thirteen patients with early gastric cancer. At 20 min after the injection of ICG, SNs stained with ICG were observed by a newly developed infrared ray laparoscopy system (IRLS).

Sentinel nodes were detected in all 13 cases. Sensitivity was 100 % (13/13). Mean number of SNs in the absorption imaging was 6.6 per patient and that in the fluorescence imaging was 15.7 per patient. There was no difference in the SN mapping between the absorption imaging and the fluorescence imaging. Detection of SNs using a new IRLS is a promising novel technique, which has both the absorption and the fluorescence imaging of ICG that can detect SN in real-time observation without disturbing the continuity of the operation and, moreover, no limitation in fatty patients.

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References

  1. Aikou T, Kitagawa Y, Kitajima M, Uenosono Y, Bilchik AJ, Martinez SR, Saha S. Sentinel lymph node mapping with GI cancer. Cancer Metastasis Rev. 2006;25:269–77.

    Article  PubMed  Google Scholar 

  2. Kitagawa Y, Fujii H, Kumai K, Kubota T, Otani Y, Saikawa Y, Yoshida M, Kubo A, Kitajima M. Recent advances in sentinel node navigation for gastric cancer: a paradigm shift of surgical management. J Surg Oncol. 2005;90:147–51.

    Article  PubMed  Google Scholar 

  3. Nimura H, Narimiya N, Mitsumori N, Yamazaki Y, Yanaga K, Urashima M. Infrared ray electronic endoscopy combined with indocyanine green injection for detection of sentinel nodes of patients with gastric cancer. Br J Surg. 2004;91:575–9.

    Article  CAS  PubMed  Google Scholar 

  4. Kusano M, Tajima Y, Yamazaki K, Kato M, Watanabe M, Miwa M. Sentinel node mapping guided by indocyanine green fluorescence imaging: a new method for sentinel node navigation surgery in gastrointestinal cancer. Dig Surg. 2008;25:103–8.

    Article  PubMed  Google Scholar 

  5. Miyashiro I, Miyoshi N, Hiratsuka M, Kishi K, Yamada T, Ohue M, Ohigashi H, Yano M, Ishikawa O, Imaoka S. Detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging: comparison with infrared imaging. Ann Surg Oncol. 2008;15:1640–3.

    Article  PubMed  Google Scholar 

  6. Kelder W, Nimura H, Takahashi N, Mitsumori N, van Dam GM, Yanaga K. Sentinel node mapping with indocyanine green (ICG) and infrared ray detection in early gastric cancer: an accurate method that enables a limited lymphadenectomy. Eur J Surg Oncol. 2010;36:552–8.

    Article  CAS  PubMed  Google Scholar 

  7. Takahashi N, Nimura H, Fujita T, Mitsumori N, Kashiwagi H, Yanaga K. Detection of sentinel node by fluorescence and infrared ray imaging system in gastric cancer. Ann Surg Oncol. 2009;16:1720.

    Article  PubMed  Google Scholar 

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Correspondence to Naoto Takahashi M.D., Ph.D. .

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Video 25.1

Dual absorption and fluorescence imaging (MPG 40,530 kb)

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Takahashi, N., Nimura, H., Fujisaki, M., Mitsumori, N., Yanaga, K. (2015). A Dual Infrared Ray Imaging System for Sentinel Node Mapping Against Early Gastric Cancer: Absorption and Florescence Methods by Infrared Ray Laparoscopy System Combined with Indocyanine Green. In: Dip, F., Ishizawa, T., Kokudo, N., Rosenthal, R. (eds) Fluorescence Imaging for Surgeons. Springer, Cham. https://doi.org/10.1007/978-3-319-15678-1_25

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  • DOI: https://doi.org/10.1007/978-3-319-15678-1_25

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-15677-4

  • Online ISBN: 978-3-319-15678-1

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