Abstract
A group of long chin heteroglycans or heteropolysaccharides consisting of N-acetylhexosamine, hexuronic acid or hexose as repeating units, occurring in animal tissues, is termed “Mucopolysaccharide” (MPS). Some of these polysaccharides are also polyelectrolytes, behaving as polyanionic substances due to the presence of free carboxylic (--COO−) and sulphate (--SO3 =) groups. Such acidic mucopolysaccharides (AMPS) mainly occur in connective tissues and universally contain acetylated hexosamine. Jeanloz [1]; termed these MPS as Glycosaminoglycans (GAG) (Fig. 8.1).
†Authors was deceased at the time of publication.
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References
Jeanloz RW. Chemical structure of the polysaccharides of connective tissue (mucopolysaccharides). Bull Soc Chim Biol. Paris. 1960;42:1829–31.
Stacey M. The chemistry of mucopolysaacharides and mucoproteins. Adv Carbohydr Chem. 1946;2:161.
Stacey M, Barker SA. Carbohydrates of living tissues. London: van. Nostrand; 1962.
Tsiganos TCP, Muir H. In: Vogell HG (ed.). Connective tissue and ageing, Amsterdam: Excerpta Medica; 1973;1:132.
Hopwood JJ, Robinson HC. The structure and composition of cartilage keratin sulphate. Biochem J. 1974;141:517.
Buedecke E, Kroz W, Tittor W. Hoppe-Seyler’s. Z Physiol Chem. 1967;384:651.
Rosenberg L, Hellman AK, Kleinschmit WJ. Macromolecular models of protein-polysaccharide from bovine nasal cartilage based on electron microscope studies. London: London Academic Press, Biol Chem. 1970;245:4123.
Hascall VC, Riolo REJ. Characteristics of the protein-keratan sulfate core and of keratan sulfate prepared from bovine nasal cartilage proteoglycan. J Biol Chem. 1972;247:4529.
Grossman BJ, Dorfman A. In vitro comparison of the antithrombic action of heparin and chondroitinsulfuric acid-B. Pediatrics. 1957;20:506.
Leoewi G, Mdyer K. The acid mucopolysaccharides of embryonic skin. Biochim Biophys Acta. 1958;27:453.
Dorfman A, Schiller S. Biological structure and function, London: Academic; 1961;1. p. 328.
Stryer L. Energy transfer in proteins and polypeptides. Rad Res. 1960;(Suppl. 2):432–51.
Spiers CH. Das Wasseraufnahmevermogen von Kollagen und Leder. J Soc Leather Trades’ Chem. 1952;36:20.
Eder HA. Determination of the thiocyanate space. In: Visscher MB (ed.). Methods in medical research, Chicago: Yearbook Publishers, 1951;4:48–53.
Singh M, Bachhawat BK. Isolation and characterization of glysoaminoglycans in human brain of different age groups. J Neurochem. 1968;15:249–58.
Schiller S, Slover GA, Dorfman AJ. A method for the separation of acid mucopolysaccharides: its application to the isolation of heparin from the skin of rats. Biol Chem. 1961;236:983.
Scott JE. In: Glick D (ed.). Methods on biochemical analysis. New York: Inter Science Publishers; 1960;8:145.
Dische Z. A new specific color reaction of hexuronic acids. J Biol Chem. 1947;167:189.
Bitter T, Muir HM. A modified uronic acid carbazole reaction. Anal Biochem. 1962;4:330–4.
Elson LA, Morgan WT. A colorimetric method for the determination of glucosamine and chondrosamine. Biochem J. 1933;27(6):1824–8.
Morgan WT, Elson LA. A colorimetric method for the determination of N-acetylglucosamine and N-acetylchrondrosamine. Biochem J. 1934;28:988.
Ludowieg J, Bewrmaman JD. A method for analysis of amino sugars: specificity and mechanism of the reaction. Carbohydr Res. 1968;8:185–92.
Dodgson KS, Price RG. A note on the determination of the ester sulphate content of sulphated polysaccharides. Biochem J. 1962;84:106.
Ghosh S, Blumenthal HJ, Davidson E, Roseman S. Glucosamine metabolism. V. Enzymatic synthesis of glucosamine 6-phosphate. J Biol Chem. 1960;235:1265–73.
Lowery OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265.
Spiro RG. Studies on the biosynthesis of glucosamine in the intact rat. J Biol Chem. 1959;234:742–8.
Winterburn PJ, Phelps CF. Purification and some kinetic properties of rat liver glucosamine synthetase. Biochem J. 1971;121(4):701–9.
Harwitz AL, Crystal RC. Content and synthesis of glycosaminoglycans in the developing lung. J Clin Invest. 1975;56(5):1312–8.
Kauffman SL, Burris PH, Weibal ER. The post-natal growth of the rat lung. II. Autoradiography. Anat Rec. 1974;180:63–76.
Margolis RU, Margolis RK, Chang LB, Preti C. Glycosaminoglycans of brain during development. Biochem. 1975;14(1):85–8.
Laurent TC, Barany EH, Carlsson B, Tidare E. Determination of hyaluronic acid in the microgram range. Anal Biochem. 1969;31:133–45.
Bourke RS, Tower DB. Fluid compartmentation and electrolytes of cat cerebral cortex in vitro–II sodium, potassium and chloride of mature cerebral cortex. J Neurochem. 1966;13(11):1099–117.
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Ganguly, C., Thakurata, G.G., Mukherjee, K.L., Bhattacharya, N. (2016). Mucopolysaccharides, Water and Electrolytes of Human Fetal Organs. In: Bhattacharya, N., Stubblefield, P. (eds) Human Fetal Growth and Development. Springer, Cham. https://doi.org/10.1007/978-3-319-14874-8_8
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