Abstract
The search for new anticancer drugs in the last years has shown its limits: no new molecule has been approved in recent years. Indeed, the last time we have seen the birth of only drugs "targeted therapy", which, as we know, are monoclonal antibodies. They are able to modify or block, starting from membrane receptors, intracellular signals, signal transduction pathways, without producing a persistent positive reaction towards neoplasia. In this situation came to rescue all natural medications with their active ingredients most suitable. Studies in Basic Searching the observations with traditional methods and the presentation of the first results of phase I and phase II are attracting a lot of attention. The discovery of the positive interaction use with chemotherapy and radiotherapy of substances such as polydatin, lactoferrin, boswellia serrata or curcumin and dozens of other natural substances has opened a new treatment scenario: the Integrative Oncology. The study of the possible synergistic interaction between chemotherapeutic drugs and natural substances has given rise to new researches. The Italian group of oncologists which belongs to the Association A.R.T.O.I. (Association of Integrative Oncology Therapies Research) had the strength and the courage to try these drugs integration. Observational studies have yielded first results of studies with Polydatin and AHCC. The benefit is visible through our treated cases.
The Integrative Oncology is the new reality for patients
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References
Abdulrhman M et al (2012) Honey and a mixture of honey, beeswax and olive oil-propolis extract in treatment of chemotherapy-induced oral mucositis. A randomised controlled pilot study. Pediatr Hematol Oncol 29(3):285–292
Barton D et al (2010) Pilot study of Panax quinquefolium (American ginseng) to improve cancer-related fatigue: a randomised, double-blind, dose finding evaluation. Support Care Cancer 18(2):179–187
De Maria S (2013) Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell. J Transl Med 11:264
Epelbaum R et al (2010) Curcumin and gemcitabine in patients with advanced pancreatic cancer. Nutr Cancer 62(8):1137–1141
Ishiguro A et al (1999) Anti-carcinogenic activity of AHCC and PMP. The 2nd annual meeting of the Japanese society of alternative medicine and treatment Sapporo, Japan
Kirste S et al (2011) Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 117(16):3788–3795
Ligo M et al (2014) Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine. Biometals 27(5):1017–1029
McCulloch M et al (2006) Astragalus based Chinese herbs and platinum based chemotherapy for advanced non small cell lung camcer: meta-analisis of randomised trial. J Clin Oncol 24(3):419–430
Ravagnan G et al (2013) Polydatin, a natural precursor of resveratrol, induces β-defensin production and reduces inflammatory response. Inflammation 36(1):26–34
Sugamuna M et al (2011) New cancer treatment strategy using combination of green tea catechins and anticancer drugs. Cancer Sci 102(2):317–323
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Bonucci, M. (2015). Integrative Oncology: Scientific Research in Support of Patients: Useful, Possible, Valid. In: Gandhi, V., Mehta, K., Grover, R., Pathak, S., Aggarwal, B. (eds) Multi-Targeted Approach to Treatment of Cancer. Adis, Cham. https://doi.org/10.1007/978-3-319-12253-3_25
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DOI: https://doi.org/10.1007/978-3-319-12253-3_25
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