Abstract
Adipose tissue is the main site of energy storage in the form of triglycerides. Mature adipocytes also produce enzymes, growth factors, cytokines, chemokines, and hormones (adipokines) implicated in the modulation of feeding, energy homeostasis, lipid and glucose metabolism, inflammation, coagulation, and cardiovascular system. Obesity alters the expression, circulating levels, and signaling mechanisms of adipose-secreted factors, and these changes have been linked to the development of insulin resistance, type 2 diabetes, dyslipidemia, atherosclerosis, cancer, and other diseases.
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References
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This work was supported by grant P01-DK-049210 from the National Institutes of Health, USA.
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Ahima, R.S., Scolaro, L.M., Park, HK. (2015). Adipokines and Metabolism. In: Ahima, R. (eds) Metabolic Syndrome. Springer, Cham. https://doi.org/10.1007/978-3-319-12125-3_24-1
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DOI: https://doi.org/10.1007/978-3-319-12125-3_24-1
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DOI: https://doi.org/10.1007/978-3-319-12125-3_24-3
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DOI: https://doi.org/10.1007/978-3-319-12125-3_24-1