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Assessing Individualized Medicine—The Example of Immunoadsorption

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Individualized Medicine

Part of the book series: Advances in Predictive, Preventive and Personalised Medicine ((APPPM,volume 7))

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Abstract

Biomarkers can be used for the prediction of treatment response within the context of widespread diseases. The aim of this contribution is to address this issue from the economic perspective. Based on time studies and investigations of used resources at the University Medicine Greifswald some preliminary results for the costs of the Immunoadsorption therapy with subsequent IgG (IA/IgG) substitution and the corresponding gene expression analysis are provided. Under the current setting the latter can be regarded as diagnostics for deciding, if IA/IgG is appropriate. Currently, both parts of the IM tandem are not implemented in combination in clinical routine. It is argued that the reimbursement system has a critical role for providing incentives for health care providers to translate research into routine. In addition some preliminary results of outcome evaluation based on disease-related quality of life are provided.

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Acknowledgments

This work is part of the research project Greifswald Approach to Individualized Medicine (GANI_MED). It was also supported by the German Research Foundation (DFG) via a grant to the SFBTRR 19.

The authors would like to thank S. Ameling from University of Greifswald, Interfaculty Institute for Genetics and Functional Genomics; and N. Bading, S. Blaut, M. Fritsche, S. Gailute, A. Heidmann, C. Heinrigs, M. Hiltscher, K. Hopert, S. Hübner, S. Ringhand, A. Sachse, M. Schubert, S. Sebeke, K. Sienknecht, S. Simonsen, T. Strödel, T. Suchsland and J. Zwingmann for their participation in the time studies.

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Authors and Affiliations

  1. Rechts- und Staatswissenschaftliche Fakultät, Lehrstuhl für Allgemeine Betriebswirtschaftslehre und Gesundheitsmanagement, Ernst-Moritz-Arndt-Universität Greifswald, Friedrich-Loeffler-Str. 70, 17487, Greifswald, Germany

    Paul Marschall, Timm Laslo & Steffen Flessa

  2. Institut für Community Medicine Abt. VC, Universitätsmedizin Greifswald, Ellernholzstr. 1–2, 17489, Greifswald, Germany

    Wolfgang Hoffmann & Kerstin Weitmann

Authors
  1. Paul Marschall
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  2. Timm Laslo
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  3. Wolfgang Hoffmann
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  4. Kerstin Weitmann
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  5. Steffen Flessa
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Corresponding author

Correspondence to Paul Marschall .

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Editors and Affiliations

  1. University Medicine Greifswald, Department for Ethics, Theory and History in Life Sciences, Greifswald, Germany

    Tobias Fischer

  2. University of Greifswald, GANI_MED – Greifswald Approach to Individualized Medicine, Greifswald, Germany

    Martin Langanke

  3. University of Greifswald, GANI_MED – Greifswald Approach to Individualized Medicine, Greifswald, Germany

    Paul Marschall

  4. University Medicine of Johannes Gutenberg-University Mainz, Institute for History, Theory and Ethic of Medicine, Mainz, Germany

    Susanne Michl

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Marschall, P., Laslo, T., Hoffmann, W., Weitmann, K., Flessa, S. (2015). Assessing Individualized Medicine—The Example of Immunoadsorption. In: Fischer, T., Langanke, M., Marschall, P., Michl, S. (eds) Individualized Medicine. Advances in Predictive, Preventive and Personalised Medicine, vol 7. Springer, Cham. https://doi.org/10.1007/978-3-319-11719-5_14

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  • DOI: https://doi.org/10.1007/978-3-319-11719-5_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-11718-8

  • Online ISBN: 978-3-319-11719-5

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