Abstract
Fluid resuscitation affects blood flow and oxygen concentration which is a direct function of hematocrit and hemoglobin saturation. Administered fluid increases blood flow and oxygen delivery rate but also decreases blood oxygen concentration. This study aims at analyzing the effects of changing blood flow, hematocrit and hemoglobin saturation on oxygen supply to tissue. For this purpose a novel tissue model composed of a set of cascaded and coaxial tissue cylinders was developed. Simulation results showed that oxygen diffusion has higher sensitivity to changes in hematocrit and hemoglobin saturation than to changes in blood flow. Therefore, increasing oxygen carriers and hemoglobin saturation is essential for improving fluid therapy outcomes.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Siam, J., Barnea, O. (2015). Oxygen Transfer to Tissue in Fluid Resuscitation. In: Lacković, I., Vasic, D. (eds) 6th European Conference of the International Federation for Medical and Biological Engineering. IFMBE Proceedings, vol 45. Springer, Cham. https://doi.org/10.1007/978-3-319-11128-5_5
Download citation
DOI: https://doi.org/10.1007/978-3-319-11128-5_5
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-11127-8
Online ISBN: 978-3-319-11128-5
eBook Packages: EngineeringEngineering (R0)