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Other Malignant Neoplasms

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The Bethesda System for Reporting Cervical Cytology

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Abstract

Malignant neoplasms, other than squamous and adenocarcinoma, infrequently involve the uterine cervix but nevertheless present in cervical cytologic preparations. Most often these tumors are uncommon gynecologic primaries arising in the uterine corpus or adnexa that appear in the cervical preparation, either as exfoliated cells, or via direct sampling of tumors that involve the cervix or vagina by direct extension. Secondary or metastatic tumors to the uterine cervix are seen rarely, owing to the nature of the lymphatic drainage and low vascularity of the cervix. In general, a definitive classification of the tumors described in this chapter may not be possible on cytologic preparations alone because of limited sampling and cytomorphologic overlap with other entities, creating interpretation pitfalls. However, familiarity with these entities is useful when unusual tumor morphology is encountered. Recognition of these rare tumors may help decrease the potential for misinterpretation and allow for more appropriate patient management.

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Author information

Authors and Affiliations

  1. Department of Pathology, The George Washington University, 2120 L Street, NW, Gelman Building, 2nd Floor, Suite 200, Washington, DC, 20037, USA

    Sana O. Tabbara MD

  2. Department of Pathology and Laboratory Medicine, GE Clarient Diagnostic Services, National Guard Health Affairs Hospital, King Abdulaziz Medical City, Riyadh, KSA

    Walid E. Khalbuss MD, PhD, FIAC

Authors
  1. Sana O. Tabbara MD
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  2. Walid E. Khalbuss MD, PhD, FIAC
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Corresponding author

Correspondence to Sana O. Tabbara MD .

Editor information

Editors and Affiliations

  1. Department of Pathology, Northwestern Memorial Hospital, Chicago, Illinois, USA

    Ritu Nayar

  2. Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

    David C. Wilbur

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Tabbara, S.O., Khalbuss, W.E. (2015). Other Malignant Neoplasms. In: Nayar, R., Wilbur, D. (eds) The Bethesda System for Reporting Cervical Cytology. Springer, Cham. https://doi.org/10.1007/978-3-319-11074-5_7

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  • DOI: https://doi.org/10.1007/978-3-319-11074-5_7

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-11073-8

  • Online ISBN: 978-3-319-11074-5

  • eBook Packages: MedicineMedicine (R0)

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