Skip to main content

In Vivo MRI Based Prostate Cancer Identification with Random Forests and Auto-context Model

  • Conference paper
Machine Learning in Medical Imaging (MLMI 2014)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 8679))

Included in the following conference series:

Abstract

Prostate cancer is one of the major causes of cancer death for men. Magnetic Resonance (MR) image is being increasingly used as an important modality to detect prostate cancer. Therefore, identifying prostate cancer in MRI with automated detection methods has become an active area of research, and many methods have been proposed to identify the prostate cancer. However, most of previous methods only focused on identifying cancer in the peripheral zone, or classifying suspicious cancer ROIs into benign tissue and cancer tissue. In this paper, we propose a novel learning-based multi-source integration framework to directly identify the prostate cancer regions from in vivo MRI. We employ the random forest technique to effectively integrate features from multi-source images together for cancer segmentation. Here, the multi-source images include initially only the multi-parametric MRIs (T2, DWI, eADC and dADC) and later also the iteratively estimated and refined tissue probability map of prostate cancer. Experimental results on 26 real patient data show that our method can accurately identify the cancerous tissue.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Siegel, R., et al.: Cancer statistics, 2012. CA: A Cancer Journal for Clinicians 62(1), 10–29 (2012)

    Article  Google Scholar 

  2. Schröder, F.H., et al.: Screening and Prostate-Cancer Mortality in a Randomized European Study. NEJM 360(13), 1320–1328 (2009)

    Article  Google Scholar 

  3. Hambrock, T., et al.: Prospective Assessment of Prostate Cancer Aggressiveness Using 3-T Diffusion-Weighted Magnetic Resonance Imaging–Guided Biopsies Versus a Systematic 10-Core Transrectal Ultrasound Prostate Biopsy Cohort. European Urology 61(1), 177–184 (2012)

    Article  MathSciNet  Google Scholar 

  4. Hoeks, C.M.A., et al.: Prostate Cancer: Multiparametric MR Imaging for Detection, Localization, and Staging. Radiology 261(1), 46–66 (2011)

    Article  Google Scholar 

  5. Lim, H.K., et al.: Prostate Cancer: Apparent Diffusion Coefficient Map with T2-weighted Images for Detection—A Multireader Study. Radiology, 145–151 (2009)

    Google Scholar 

  6. Sedat, O., et al.: Supervised and unsupervised methods for prostate cancer segmentation with multispectral MRI. Medical Physics 37(4), 1873–1883 (2010)

    Article  Google Scholar 

  7. Niaf, E., et al.: Computer-aided diagnosis of prostate cancer in the peripheral zone using multiparametric MRI. Phys. Med. Biol. 57(12), 3833–3851 (2012)

    Article  Google Scholar 

  8. Litjens, G., et al.: Computer-Aided Detection of Prostate Cancer in MRI. T-MI 33(5), 1083–1092 (2014)

    Google Scholar 

  9. Breiman, L.: Random Forests. Machine Learning 45(1), 5–32 (2001)

    Article  MATH  Google Scholar 

  10. Tu, Z., Bai, X.: Auto-Context and Its Application to High-Level Vision Tasks and 3D Brain Image Segmentation. PAMI 32(10), 1744–1757 (2010)

    Article  Google Scholar 

  11. Loog, M., Ginneken, B.: Segmentation of the posterior ribs in chest radiographs using iterated contextual pixel classification. T-MI 25(5), 602–611 (2006)

    Google Scholar 

  12. Mohsen, F., et al.: Detection and Localization of Prostate Cancer: Correlation of 11C-Choline PETCT with Histopathologic Step-Section Analysis. JNM 46(10), 1642–1649 (2005)

    Google Scholar 

  13. Viola, P., et al.: Robust Real-Time Face Detection. IJCV 57(2), 137–154 (2004)

    Article  Google Scholar 

  14. Han, X.: Learning-Boosted Label Fusion for Multi-atlas Auto-Segmentation. In: Wu, G., Zhang, D., Shen, D., Yan, P., Suzuki, K., Wang, F. (eds.) MLMI 2013. LNCS, vol. 8184, pp. 17–24. Springer, Heidelberg (2013)

    Chapter  Google Scholar 

  15. Cheng, H., et al.: Sparsity induced similarity measure for label propagation. In: ICCV, pp. 317–324 (2009)

    Google Scholar 

  16. Wright, J., et al.: Sparse Representation for Computer Vision and Pattern Recognition. Proceedings of the IEEE 98, 1031–1044 (2010)

    Article  Google Scholar 

  17. Yoav, F., et al.: A decision-theoretic generalization of on-line learning and an application to boosting. JCSS 55(1), 119–139 (1997)

    Article  MATH  Google Scholar 

  18. Zikic, D., Glocker, B., Criminisi, A.: Atlas Encoding by Randomized Forests for Efficient Label Propagation. In: Mori, K., Sakuma, I., Sato, Y., Barillot, C., Navab, N. (eds.) MICCAI 2013, Part III. LNCS, vol. 8151, pp. 66–73. Springer, Heidelberg (2013)

    Chapter  Google Scholar 

  19. Peng, Y., et al.: Quantitative Analysis of Multiparametric Prostate MR Images: Differentiation between Prostate Cancer and Normal Tissue and Correlation with Gleason Score—A Computer-aided Diagnosis Development Study. Radiology 267(3), 787–796 (2013)

    Article  Google Scholar 

  20. Greve, D.N., Fischl, B.: Accurate and robust brain image alignment using boundary-based registration. NeuroImage 48(1), 63–72 (2009)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this paper

Cite this paper

Qian, C., Wang, L., Yousuf, A., Oto, A., Shen, D. (2014). In Vivo MRI Based Prostate Cancer Identification with Random Forests and Auto-context Model. In: Wu, G., Zhang, D., Zhou, L. (eds) Machine Learning in Medical Imaging. MLMI 2014. Lecture Notes in Computer Science, vol 8679. Springer, Cham. https://doi.org/10.1007/978-3-319-10581-9_39

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-10581-9_39

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-10580-2

  • Online ISBN: 978-3-319-10581-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics