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Ultrastructure of Myelinated and Unmyelinated Axons

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Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine

Abstract

The macroscopic anatomy of peripheral nerves results from the hierarchic arrangement of nerve fibers formed by microscopic groups of motor and sensory neuronal cytoplasmic elongations known as axons. The latter enable conduction of electrical impulses along their plasma membranes, as well as chemically mediated signal transduction throughout cytoplasmic organelles. Most peripheral nerves are mixed nerves containing efferent motor fibers, afferent sensory fibers, and sympathetic fibers. The initial segment of an axon (AIS) originates in the soma and is located between the cell body and the beginning of the myelin sheath

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References

  1. Reina MA, Arriazu R, Collier CB, Sala-Blanch X. Histology and electron microscopy of human peripheral nerves of clinical relevance to the practice of nerve blocks. Rev Esp Anestesiol Reanim. 2013;60:552–62.

    Article  CAS  PubMed  Google Scholar 

  2. Reina MA, López A, Villanueva MC, De Andrés JA, León GI. Morfología de los nervios periféricos, de sus cubiertas y de su vascularización. Rev Esp Anestesiol Reanim. 2000;47:464–75.

    CAS  PubMed  Google Scholar 

  3. Reina MA, De Andres JA, Hernández JM, Arriazu Navarro R, Durán Mateos EM, Prats-Galino A. Successive changes in extraneural structures from the subarachnoid nerve roots to the peripheral nerve, influencing anesthetic block, and treatment of acute postoperative pain. Eur J Pain Suppl. 2011;5:377–85.

    Article  Google Scholar 

  4. De Andrés JA, Reina MA, López A, Sala-Blanch X, Prats A. Blocs nerveux périphériques, paresthésies et injections intraneurales. Le Practicien En Anesth Réanim. 2010;14:213–21.

    Article  Google Scholar 

  5. Berthold CH, Fraher JP, King RHM, Rydmark M. Microscopic anatomy of the peripheral nervous system. In: Dyck PJ, Thomas PK, editors. Peripheral neuropathy. 4th ed. Philadelphia: Elsevier; 2005. p. 35–91.

    Chapter  Google Scholar 

  6. Peters A, Palay SL, Webster HF. The axon. In: Peters A, Palay SL, Webster HF, editors. The fine structure of the nervous system. 3rd ed. New York: Oxford University Press; 1991. p. 101–39.

    Google Scholar 

  7. Kleitman N, Bunge RP. The Schwann cell: morphology and development. In: Waxman SG, Kocsis JD, Stys PK, editors. The axon. New York: Oxford University Press; 1995. p. 97–115.

    Chapter  Google Scholar 

  8. King RHM. Unmyelinated fibers. In: Dyck PJ, Thomas PK, editors. Peripheral neuropathy, vol. 1. 4th ed. Philadelphia: Elsevier; 2005. p. 62–7.

    Google Scholar 

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Correspondence to Miguel Angel Reina MD, PhD .

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Reina, M.A., Arriazu Navarro, R., Durán Mateos, E.M. (2015). Ultrastructure of Myelinated and Unmyelinated Axons. In: Reina, M., De Andrés, J., Hadzic, A., Prats-Galino, A., Sala-Blanch, X., van Zundert, A. (eds) Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-09522-6_1

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  • DOI: https://doi.org/10.1007/978-3-319-09522-6_1

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-09522-6

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