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Mesoscopic Models for the Overstretching Transition of DNA

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Extended Abstracts Spring 2013

Part of the book series: Trends in Mathematics ((RPCRMB,volume 2))

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Abstract

One of the most intriguing and only partially clear phenomenon concerning the mechanical properties of DNA is the so-called overstretching transition [2, 7]. It consists in a sudden elongation of the DNA chain of about 70 % more than the native length (B-DNA), when a force around 70 pN is applied. Three main mechanisms have been proposed to explain this transition. Two of them involve breaking of the bonds that hold the two strands together: peeling from nicks or free ends of the chain; and inside-strand separation (M-DNA) [10–12].

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Author information

Authors and Affiliations

  1. Departamento de Física de la Materia Condensada, Universidad de Zaragoza, Zaragoza, Spain

    Ana Elisa Bergues Pupo, Alessandro Fiasconaro & Fernando Falo

  2. Departamento de Física, Universidad de Oriente, Santiago de Cuba, Cuba

    Ana Elisa Bergues Pupo

  3. Instituto de Ciencia de Materiales de Aragón, CSIC, Zaragoza, Spain

    Alessandro Fiasconaro

  4. Instituto de Biocomputación y Física de Sistemas Complejos (BIFI), Universidad de Zaragoza, Zaragoza, Spain

    Fernando Falo

Authors
  1. Ana Elisa Bergues Pupo
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  2. Alessandro Fiasconaro
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  3. Fernando Falo
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Corresponding author

Correspondence to Ana Elisa Bergues Pupo .

Editor information

Editors and Affiliations

  1. Centre de Recerca Matemàtica, Barcelona, Spain

    Álvaro Corral

  2. MPI Physics of Complex Systems, Dresden, Germany

    Anna Deluca

  3. Centre de Recerca Matemàtica, Barcelona, Spain

    Francesc Font-Clos

  4. Department of Mathematics, University College London, London, United Kingdom

    Pilar Guerrero

  5. Centre de Recerca Matemàtica, Barcelona, Spain

    Andrei Korobeinikov

  6. Departament d'Enginyeria Química, Universitat Rovira i Virgili, Tarragona, Spain

    Francesco Massucci

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Pupo, A.E.B., Fiasconaro, A., Falo, F. (2014). Mesoscopic Models for the Overstretching Transition of DNA. In: Corral, Á., Deluca, A., Font-Clos, F., Guerrero, P., Korobeinikov, A., Massucci, F. (eds) Extended Abstracts Spring 2013. Trends in Mathematics(), vol 2. Birkhäuser, Cham. https://doi.org/10.1007/978-3-319-08138-0_1

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