Skip to main content
SpringerLink
Log in

Unclassified Neuropathies and Mimics

  • Chapter
  • First Online:
Biopsy Diagnosis of Peripheral Neuropathy

  • 2182 Accesses

Abstract

Some polyneuropathies which have not been discussed elsewhere in this monograph deserve specific mention. Some of these are parts of clinical syndromes, while others are specific entities. Although mitochondrial diseases might well be considered to be “genetically determined,” they are also considered here. Peripheral neuropathy resulting from a mitochondrial defect associated with MFN2 and GDAP1 mutations has been addressed as part of the CMT group of peripheral nerve disorders and will not be readdressed here.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Angel MJ, Bril V, Shannon P et al (2007) Neuromuscular function in survivors of the acute respiratory distress syndrome. Can J Neurol Sci 34:427–432

    PubMed  Google Scholar 

  • Arnold WD, Elsheikh BH (2013) Entrapment neuropathies. Neurol Clin 31:405–424

    PubMed  Google Scholar 

  • Atsumi T, Yakamura Y, Sato T, Ikuta F (1980) Hirano bodies in the axon of peripheral nerves in a case with progressive external ophthalmoplegia with multisystemic involvement. Acta Neuropathol 49:95–100

    CAS  PubMed  Google Scholar 

  • Averback P, Langevin H (1978) Corpora amylacea of the lumbar spinal cord and peripheral nervous system. Arch Neurol 35:95–96

    CAS  PubMed  Google Scholar 

  • Bardosi A, Creutzfeldt W, DiMauro S et al (1987) Myo-, neuro-, gastrointestinal encephalopathy (MNGIE syndrome) with partial deficiency of cytochrome C oxidase. A new mitochondrial multisystem disorder. Acta Neuropathol 74:248–253

    CAS  PubMed  Google Scholar 

  • Ben Hamida M, Letaief F, Hentati F, Ben Hamida C (1987) Morphometric study of the sensory nerve in classical (or Charcot disease) and juvenile amyotrophic lateral sclerosis. J Neurol Sci 78:313–329

    CAS  PubMed  Google Scholar 

  • Berkovic SF, Andermann F, Shoubridge EA et al (1991) Mitochondrial dysfunction in multiple symmetrical lipomatosis. Ann Neurol 29:566–569

    CAS  PubMed  Google Scholar 

  • Bernsen RAJAM, Busard HLSM, Ter Lakk HJ et al (1989) Polyglucosan bodies in intramuscular motor nerves. Acta Neuropathol 77:629–633

    CAS  PubMed  Google Scholar 

  • Bolton CF, Young GB, Zochodne DW (1993) The neurological complications of sepsis. Ann Neurol 33:94–100

    CAS  PubMed  Google Scholar 

  • Bradley WG, Good P, Rasool CG, Adelman LS (1983) Morphometric and biochemical studies of peripheral nerves in amyotrophic lateral sclerosis. Ann Neurol 14:267–277

    CAS  PubMed  Google Scholar 

  • Bruno C, Servidei S, Shanske S et al (1992) Glycogen branching enzyme in adult polyglucosan body disease. Neurology 42(Suppl 3):230 (abstr)

    Google Scholar 

  • Busard HLSM, Gabreels-Festen AAWM, Van’t Hoff MA et al (1990) Polyglucosan bodies in sural nerve biopsies. Acta Neuropathol 80:554–557

    CAS  PubMed  Google Scholar 

  • Busard HLSM, Gabreels-Festen AAWM, Renier WO et al (1991) Adult polyglucosan body disease: the diagnostic value of axilla skin biopsy. Ann Neurol 29:448–451

    CAS  PubMed  Google Scholar 

  • Cafferty MS, Lovelace RE, Hays AP et al (1991) Polyglucosan body disease. Muscle Nerve 14:102–107

    CAS  PubMed  Google Scholar 

  • Carpenter S, Karpati G, Rothman S et al (1978) Pathological involvement of primary sensory neurons in Werdnig-Hoffman disease. Acta Neuropathol 42:91–97

    CAS  PubMed  Google Scholar 

  • Cavanagh JB (1999) Corpora amylacea and the family of polyglucosan diseases. Brain Res 29:265–295

    CAS  Google Scholar 

  • Chalk CH, Mills KR, Jacobs JM, Donaghy M (1990) Familial multiple symmetric lipomatosis with peripheral neuropathy. Neurology 40:1246–1250

    CAS  PubMed  Google Scholar 

  • Chusid MJ, Dale DC, West BD, Wolff SM (1975) The hypereosinophilic syndrome. Analysis of 14 cases with review of the literature. Medicine 54:1–27

    CAS  PubMed  Google Scholar 

  • Dalakas MC (1986) Chronic idiopathic ataxic neuropathy. Ann Neurol 19:545–554

    CAS  PubMed  Google Scholar 

  • Dayan AD, Graveson GS, Illis S, Robinson PK (1969) Schwann cell damage in motoneuron disease. Neurology 19:242–246

    CAS  PubMed  Google Scholar 

  • di Trapani G, David P, La Cara A et al (1986) Morphological studies of sural nerve biopsies in the pseudopolyneuropathic form of amyotrophic lateral sclerosis. Clin Neuropathol 5:134–138

    PubMed  Google Scholar 

  • Dorfman LJ, Ransom BR, Forno LS, Kelts A (1983) Neuropathy in the hypereosinophilic syndrome. Muscle Nerve 6:291–298

    CAS  PubMed  Google Scholar 

  • Drachman DA (1968) Ophthalmoplegia plus. The neurodegenerative disorders associated with progressive external ophthalmoplegia. Arch Neurol 18:654–674

    CAS  PubMed  Google Scholar 

  • Dyck PJ, Stevens JC, Mulder DW, Espinosa RE (1975) Frequency of nerve fiber degeneration of peripheral motor and sensory neurons in amyotrophic lateral sclerosis: morphometry of deep and superficial peroneal nerves. Neurology 25:781–785

    CAS  PubMed  Google Scholar 

  • Emory TS, Scheithauer BW, Hirose T et al (1995) Intraneural perineurioma. A clonal neoplasm associated with abnormalities of chromosome 22. Am J Clin Pathol 103:696–704

    CAS  PubMed  Google Scholar 

  • Enzi G (1984) Multiple symmetric lipomatosis: an updated clinical report. Medicine 63:56–64

    CAS  PubMed  Google Scholar 

  • Enzi G, Angelini C, Negrin P et al (1986) Sensory, motor, and autonomic neuropathy in patients with multiple symmetrical lipomatosis. Medicine 64:388–393

    Google Scholar 

  • Eymard B, Penicaud A, Leger JM et al (1991) Etude clinique et electrophysiologique du nerf peripherique dans 28 cas de maladie mitochondriale. Rev Neurol 147:508–512

    CAS  PubMed  Google Scholar 

  • Fadic R, Russell JA, Vedanarayanan VV et al (1997) Sensory ataxic neuropathy as the presenting feature of a novel mitochondrial disease. Neurology 49:239–245

    CAS  PubMed  Google Scholar 

  • Finsterer J (2005) Mitochondrial neuropathy. Clin Neurol Neurosurg 107:181–186

    PubMed  Google Scholar 

  • Fletcher SN, Kennedy DD, Ghosh IR et al (2003) Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illness. Crit Care Med 31:1012–1016

    PubMed  Google Scholar 

  • Frequin ST, Gabreels FJ, Gabreels-Festen AAWM, Joosten EMG (1991) Sensory axonopathy in hereditary distal spinal muscular atrophy. Clin Neurol Neurosurg 93:323–326

    CAS  PubMed  Google Scholar 

  • Fukuhara N (1977) Intra-axonal corpora amylacea in the peripheral nerve seen in a healthy woman. J Neurol Sci 34:423–426

    CAS  PubMed  Google Scholar 

  • Garcia Garcia A, Lopez Messa J, Aparicio Duque R (1991) Peripheral polyneuropathy complicating conditions of sepsis and multi organ failure. Electromyogr Clin Neurophysiol 31:181–186

    CAS  PubMed  Google Scholar 

  • Gemignami F, Juvarra G, Marbini A et al (1982) Polyneuropathy in progressive external ophthalmoplegia. Eur Neurol 21:181–188

    Google Scholar 

  • Gherardi R, Bouche P, Escourolle R et al (1983) Peroneal muscular atrophy. Part 2. Nerve biopsy studies. J Neurol Sci 61:401–416

    CAS  PubMed  Google Scholar 

  • Goebel HH, Bardosi A, Friede RL (1986) Sural nerve biopsy studies in Leigh’s subacute necrotizing encephalomyelopathy. Muscle Nerve 9:165–173

    CAS  PubMed  Google Scholar 

  • Gonatas NK (1967) A generalized disorder of nervous system, skeletal muscle and heart resembling Refsum’s disease and Hurler’s syndrome. Am J Med 42:169–178

    CAS  PubMed  Google Scholar 

  • Gorson KC, Ropper AH (1993) Acute respiratory failure neuropathy: a variant of critical illness polyneuropathy. Crit Care Med 21:267–271

    CAS  PubMed  Google Scholar 

  • Gray F, Gherardi R, Marshall A et al (1988) Adult polyglucosan body disease. J Neuropathol Exp Neurol 47:459–474

    CAS  PubMed  Google Scholar 

  • Griffin JW, Cornblath DR, Alexander E et al (1990) Ataxic sensory neuropathy and dorsal root ganglionitis associated with Sjogren’s syndrome. Ann Neurol 27:304–315

    CAS  PubMed  Google Scholar 

  • Grisold W, Jellinger K (1985) Multifocal neuropathy with vasculitis in hypereosinophilic syndrome: an entity or drug induced effect. J Neurol 231:301–306

    CAS  PubMed  Google Scholar 

  • Heads T, Pollock M, Robertson A et al (1991) Sensory nerve pathology in amyotrophic lateral sclerosis. Acta Neuropathol 82:316–320

    CAS  PubMed  Google Scholar 

  • Hirano M, Silvestri G, Blake DM et al (1994) Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): clinical, biochemical, and genetic features of an autosomal recessive mitochondrial disorder. Neurology 44:721–727

    CAS  PubMed  Google Scholar 

  • Hirano M, Nishigaki Y, Marti R (2004) Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a disease of two genomes. Neurologist 10:8–17

    PubMed  Google Scholar 

  • Holme E, Larsson NG, Oldfors A et al (1993) Multiple symmetric lipomas with high levels of mtDNA with the tRNA(lys) A→G(8344) mutation as the only manifestation of disease in a carrier of myoclonus epilepsy and ragged-red fibers (MERRF) syndrome. Am J Hum Genet 52:551–556

    CAS  PubMed Central  PubMed  Google Scholar 

  • Holt IJ, Harding AE, Petty RK, Morgan-Hughes JA (1990) A new mitochondrial disease associated with mitochondrial DNA heteroplasmy. Am J Hum Genet 46:428–433

    CAS  PubMed Central  PubMed  Google Scholar 

  • Jacobs JM, Harding NN, Lake BD et al (1990) Peripheral neuropathy in Leigh’s disease. Brain 113:447–462

    PubMed  Google Scholar 

  • Karpati G, Carpenter S (1983) The clinical spectrum of adult polyglucosan body disease. Neurology 33(Suppl 2):246 (abstr)

    Google Scholar 

  • Kawamura Y, Dyck PJ, Masatake S et al (1991) Morphometric comparison of the vulnerability of peripheral motor and sensory neurons in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 40:667–675

    Google Scholar 

  • Kerkoff A, Troost D, Louwerse ES et al (1993) Inflammatory cells in the peripheral nervous system in motor neuron disease. Acta Neuropathol 85:560–565

    Google Scholar 

  • Klopstock T, Naumann M, Schalke B et al (1994) Multiple symmetric lipomatosis: abnormalities in complex IV and multiple deletions in mitochondrial DNA. Neurology 44:862–866

    CAS  PubMed  Google Scholar 

  • Koshy K, Zochodne DW (2013) Chapter 44. Neuromuscular complications of critical illness. In: Said G, Krarup C (eds) Handbook of clinical neurology. Peripheral nerve disorders, vol 115 (3rd series). Elsevier BV, Amsterdam, pp 759–780

    Google Scholar 

  • Li V, Hostein J, Romero N et al (1991) Chronic intestinal pseudo-obstruction with myopathy and ophthalmoplegia: a muscular biochemical study of a mitochondrial disorder. Dig Dis Sci 37:456–463

    Google Scholar 

  • Lossos A, Barash V, Soffer D et al (1991) Hereditary branching enzyme dysfunction in adult polyglucosan body disease: a possible metabolic cause in two patients. Ann Neurol 30:655–662

    CAS  PubMed  Google Scholar 

  • Lupo I, Daniele O, Raimondo D et al (1989) Peripheral neuropathy in the hypereosinophilic syndrome: a case report. Eur Neurol 29:269–272

    CAS  PubMed  Google Scholar 

  • Mancardi GL, Schenone A, Tabaton M et al (1985) Polyglucosan bodies in sural nerve of diabetic patient with polyneuropathy. Acta Neuropathol 66:83–86

    CAS  PubMed  Google Scholar 

  • Markesbery WR (1979) Lactic acidemia, mitochondrial myopathy, and basal ganglia calcification. Neurology 29:1057–1061

    CAS  PubMed  Google Scholar 

  • Marshall A, Duchen LW (1975) Sensory system involvement in infantile spinal muscular atrophy. J Neurol Sci 26:349–359

    CAS  PubMed  Google Scholar 

  • Matsumuro K, Izumo S, Minauchi Y et al (1993) Chronic demyelinating neuropathy and intra-axonal polyglucosan bodies. Acta Neuropathol 86:95–99

    CAS  PubMed  Google Scholar 

  • McDonald TD, Faust PL, Bruno C et al (1993) Polyglucosan body disease simulating amyotrophic lateral sclerosis. Neurology 43:785–790

    CAS  PubMed  Google Scholar 

  • McLeod JG, Prineas JW (1971) Distal type of chronic spinal muscular atrophy - clinical, electrophysiological and pathological studies. Brain 94:703–714

    CAS  PubMed  Google Scholar 

  • McMaster KR, Powers JM, Hennigar GR et al (1979) Nervous system involvement in type IV glycogenosis. Arch Pathol Lab Med 103:105–111

    CAS  PubMed  Google Scholar 

  • Milde P, Guccion JG, Kelly J et al (2001) Adult polyglucosan body disease – diagnosis by sural nerve and skin biopsy. Arch Pathol Lab Med 125:519–522

    CAS  PubMed  Google Scholar 

  • Mizusawa H, Ohkoshi N, Watanabe M, Kanazawa I (1991) Peripheral neuropathy of mitochondrial myopathies. Rev Neurol 147:501–507

    CAS  PubMed  Google Scholar 

  • Mochel F, Schiffmann R, Steenweg ME et al (2012) Polyglucosan body disease: natural history and key magnetic resonance imaging findings. Ann Neurol 72:433–441

    CAS  PubMed  Google Scholar 

  • Monaco S, Lucci B, Laperchia N et al (1988) Polyneuropathy in hypereosinophilic syndrome. Neurology 38:494–496

    CAS  PubMed  Google Scholar 

  • Mondelli M, Rossi A, Passero S, Guazzi GC (1993) Involvement of peripheral sensory fibers in amyotrophic lateral sclerosis: electrophysiological study of 64 cases. Muscle Nerve 16:166–172

    CAS  PubMed  Google Scholar 

  • Moore PM, Harley JB, Fauci AS (1985) Neurologic dysfunction in the idiopathic hypereosinophilic syndrome. Ann Intern Med 102:109–114

    CAS  PubMed  Google Scholar 

  • Nardin RA, Johns DR (2001) Mitochondrial dysfunction and neuromuscular disease. Muscle Nerve 24:170–191

    CAS  PubMed  Google Scholar 

  • Nicoll JA, Moss TH, Love S et al (1993) Clinical and autopsy findings in two cases of MELAS presenting with stroke-like episodes but without clinical myopathy. Clin Neuropathol 12:38–43

    CAS  PubMed  Google Scholar 

  • Ohama E, Ohara S, Ikuta F et al (1987) Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalopathy. Acta Neuropathol 74:226–233

    CAS  PubMed  Google Scholar 

  • Pamphlett R, Walsh J (1989) Infective endocarditis with inflammatory lesions in the peripheral nervous system. Acta Neuropathol 78:101–104

    CAS  PubMed  Google Scholar 

  • Pareyson D, Piscosquito G, Moroni I et al (2013) Peripheral neuropathy in mitochondrial disorders. Lancet Neurol 12:1011–1124

    CAS  PubMed  Google Scholar 

  • Parisi TJ, Mandrekar J, Dyck PJ et al (2011) Meralgia paresthetica: relation to obesity, advanced age, and diabetes mellitus. Neurology 77:1538–1542

    PubMed Central  PubMed  Google Scholar 

  • Persson AK, Gasser A, Black JA, Waxman SG (2011) Nav1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas. Exp Neurol 230:273–279

    CAS  PubMed  Google Scholar 

  • Peyronnard JM, Charron L, Bellavance A, Marchand L (1980) Neuropathy and mitochondrial myopathy. Ann Neurol 7:262–268

    CAS  PubMed  Google Scholar 

  • Pezeshkpour G, Krarup C, Buchtal F et al (1987) Peripheral neuropathy in mitochondrial disease. J Neurol Sci 77:285–304

    CAS  PubMed  Google Scholar 

  • Pollock M, Nicholson GI, Nukada H et al (1988) Neuropathy in multiple symmetric lipomatosis. Madelung’s disease. Brain 111:1157–1171

    PubMed  Google Scholar 

  • Powell HC, Ward HW, Garrett RS et al (1979) Glycogen accumulation in the nerves and kidney of chronically diabetic rats. A quantitative electron microscope study. J Neuropathol Exp Neurol 38:114–127

    CAS  PubMed  Google Scholar 

  • Probst A, Ulrich J, Bischoff A et al (1981) Sensory ganglioneuropathy in infantile spinal muscular atrophy. Light and electron microscopic findings in two cases. Neuropediatrics 12:215–231

    CAS  PubMed  Google Scholar 

  • Robitaille Y, Carpenter S, Karpati G, DiMauro S (1980) A distinct form of adult polyglucosan body disease with massive involvement of central and peripheral neuronal processes and astrocytes. Brain 103:315–336

    CAS  PubMed  Google Scholar 

  • Saiz Hervas E, Martin Llorens M, Alvarez L (2000) Peripheral neuropathy as the first manifestation of Madelung’s disease. Br J Dermatol 143:684–686

    CAS  PubMed  Google Scholar 

  • Sasaki H, Kuzuhara S, Kanazawa I et al (1983) Myoclonus, cerebellar disorder, neuropathy, mitochondrial myopathy and ACTH deficiency. Neurology 33:1288–1293

    CAS  PubMed  Google Scholar 

  • Scheithauer BW, Woodruff JM, Spinner RJ (2010) Chapter 12. Peripheral nerve sheath tumors. In: Perry A, Brat DJ (eds) Practical surgical neuropathology. Churchill Livingstone, Philadelphia, pp 235–285

    Google Scholar 

  • Schmidt RE, Bilbao JM (in press) Chapter 21. Diseases of peripheral nerve. In: Love S, Perry A, Ironside J, Budka H (eds) Greenfield’s neuropathology, 9th edn

    Google Scholar 

  • Schroder JM (1993) Neuropathy associated with mitochondrial disorders. Brain Pathol 3:177–190

    CAS  PubMed  Google Scholar 

  • Schroder JM, Sommer C (1991) Mitochondrial abnormalities in human sural nerves: fine structural evaluation of cases with mitochondrial myopathy, hereditary and non-hereditary neuropathies, and review of the literature. Acta Neuropathol 82:471–482

    CAS  PubMed  Google Scholar 

  • Schroder JM, May R, Shin YS et al (1993) Juvenile hereditary polyglucosan body disease with complete branching enzyme deficiency (type IV glycogenosis). Acta Neuropathol 85:419–430

    CAS  PubMed  Google Scholar 

  • Simon LT, Horoupian DS, Dorfman LJ et al (1990) Polyneuropathy, ophthalmoplegia, leukoencephalopathy, and intestinal pseudo-obstruction: POLIP syndrome. Ann Neurol 28:349–360

    CAS  PubMed  Google Scholar 

  • Sobue G, Hashizume Y, Mukai E et al (1989) X-linked recessive bulbospinal neuronopathy. A clinico-pathological study. Brain 112:209–232

    PubMed  Google Scholar 

  • Sobue G, Yasuda T, Kachi T et al (1993) Chronic progressive sensory ataxic neuropathy: clinicopathologic features of idiopathic and Sjogren’s syndrome-associated cases. J Neurol 240:1–7

    CAS  PubMed  Google Scholar 

  • Sommer C, Schroder JM (1989) Hereditary motor and sensory neuropathy with optic atrophy. Arch Neurol 46:972–977

    Google Scholar 

  • Spitzer AR, Giancarlo T, Maher L et al (1992) Neuromuscular causes of prolonged ventilator dependency. Muscle Nerve 15:682–686

    CAS  PubMed  Google Scholar 

  • Stam FC, Roukema PA (1973) Histochemical and biochemical aspects of corpora amylacea. Acta Neuropathol 25:95–102

    CAS  PubMed  Google Scholar 

  • Steiner I, Steinberg A, Argov Z et al (1987) Familial progressive neuronal disease and chronic idiopathic intestinal pseudo-obstruction. Neurology 37:1046–1050

    CAS  PubMed  Google Scholar 

  • Stevens RD, Marshall SA, Cornblath DR et al (2009) A framework for diagnosing and classifying intensive care unit-acquired weakness. Crit Care Med 37:S299–S308

    PubMed  Google Scholar 

  • Steyaert A, Cisse S, Merhi Y et al (1990) Purification and polypeptide composition of corpora amylacea from aged human brain. J Neurosci Methods 31:59–64

    CAS  PubMed  Google Scholar 

  • Sunohara N, Furukawa S, Nishio T et al (1989) Neurotoxicity of human eosinophils towards peripheral nerves. J Neurol Sci 92:1–7

    CAS  PubMed  Google Scholar 

  • Tannemaat MR, Korecka J, Ehlert EM et al (2007) Human neuroma contains increased levels of semaphorin 3A, which surrounds nerve fibers and reduces neurite extension in vitro. J Neurosci 27:14260–14264

    CAS  PubMed  Google Scholar 

  • Thomas PK, King RHM, Sharma AK (1980) Changes with age in the peripheral nerves of the rat. An ultrastructural study. Acta Neuropathol 52:1–6

    CAS  PubMed  Google Scholar 

  • Threkeld AB, Miller NR, Golnik KC et al (1992) Ophthalmic involvement in myo-neuro-gastrointestinal encephalopathy syndrome. Am J Ophthalmol 114:322–328

    Google Scholar 

  • Tohgi H, Tsukagoshi H, Toyokura Y (1977) Quantitative changes of sural nerves in various neurological diseases. Acta Neuropathol 38:95–101

    CAS  PubMed  Google Scholar 

  • Uncini A, Servidei S, Silvestri G et al (1993) Ophthalmoplegia, demyelinating neuropathy, leukoencephalopathy, myopathy, and gastrointestinal dysfunction with multiple deletions of mitochondrial DNA: a mitochondrial multisystem disorder in search of a name. Muscle Nerve 17:667–674

    Google Scholar 

  • Van Goethem G, Martin JJ, Dermaut B et al (2003) Recessive POLG mutations presenting with sensory and ataxic neuropathy in compound heterozygote patients with progressive external ophthalmoplegia. Neuromuscul Disord 13:133–142

    PubMed  Google Scholar 

  • Viader A, Sasaki Y, Kim S et al (2013) Schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy. Neuron 77:886–898

    CAS  PubMed Central  PubMed  Google Scholar 

  • Vital A, Vital C (2012) Mitochondria and peripheral neuropathies. J Neuropathol Exp Neurol 71:1036–1046

    CAS  PubMed  Google Scholar 

  • Vos AJ, Joosten EM, Gabreels-Festen AA (1983) Adult polyglucosan body disease: clinical and nerve biopsy findings in two cases. Ann Neurol 13:440–444

    CAS  PubMed  Google Scholar 

  • Werner RA, Wolf LL (1990) Peripheral neuropathy associated with the hypereosinophilic syndrome. Arch Phys Med Rehabil 71:433–435

    CAS  PubMed  Google Scholar 

  • Wichman A, Buchtal F, Pezeshkpour GH et al (1985) Peripheral neuropathy in hypereosinophilic syndrome. Neurology 35:1140–1145

    CAS  PubMed  Google Scholar 

  • Windebank AJ, Blexrud MD, Dyck PJ et al (1990) The syndrome of acute sensory neuropathy: clinical features and electrophysiologic and pathologic changes. Neurology 40:584–591

    CAS  PubMed  Google Scholar 

  • Winder TR, Auer RN (1989) Sensory neuron degeneration in familial Kugelberg-Welander disease. Can J Neurol Sci 16:67–70

    CAS  PubMed  Google Scholar 

  • Witt NJ, Zochodne DW, Bolton CF et al (1991) Peripheral nerve function in sepsis and multiple organ failure. Chest 99:176–184

    CAS  PubMed  Google Scholar 

  • Yiannikas C, McLeod JG, Pollard JD, Baverstock J (1986) Peripheral neuropathy associated with mitochondrial myopathy. Ann Neurol 20:249–257

    CAS  PubMed  Google Scholar 

  • Yoshikawa H, Dyck PJ, Poduslo PJ, Giannini C (1990) Polyglucosan body axonal enlargement increases myelin spiral length but not lamellar number. J Neurol Sci 98:107–117

    CAS  PubMed  Google Scholar 

  • Zeviani M, Antozzi C (1992) Defects of mitochondrial DNA. Brain Pathol 2:121–132

    CAS  PubMed  Google Scholar 

  • Zochodne DW, Bolton CF, Wells GA et al (1987) Critical illness polyneuropathy. A complication of sepsis and multiple organ failure. Brain 110:819–842

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sunnybrook and St Michael’s Hospitals, University of Toronto, Toronto, ON, Canada

    Juan M. Bilbao MD, FRCP (C) (Professor Emeritus of Neuropathology)

  2. Division of Neuropathology Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA

    Robert E. Schmidt MD, PhD (Professor of Pathology and Immunology Director)

Authors
  1. Juan M. Bilbao MD, FRCP (C)
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Robert E. Schmidt MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Bilbao, J.M., Schmidt, R.E. (2015). Unclassified Neuropathies and Mimics. In: Biopsy Diagnosis of Peripheral Neuropathy. Springer, Cham. https://doi.org/10.1007/978-3-319-07311-8_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-07311-8_21

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-07310-1

  • Online ISBN: 978-3-319-07311-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation