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Integrated PET/CT and Linear Endosonography (EBUS and EUS)

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New Therapeutic Strategies in Lung Cancers

Abstract

Conventional imaging techniques are based on differences in tissue structure measured by differences in density (e.g. chest X-ray and CT). They allow exquisite anatomic detail and interpretation, and help in the assessment of many respiratory problems. Flexible videobronchoscopy gives an exquisite detail of the central airway mucosa, and facilitates the conventional transbronchial needle aspiration (TBNA) technique which is indicated based on information given by the CT scan. Nonetheless, structural differences often don’t allow a definitive diagnosis based on conventional imaging, or nodal size limitation and absence of anatomical landmarks do not allow a conventional invasive TBNA tissue sampling. Positron emission tomography (PET) has brought a revolutionary novelty in imaging, because it was the first test readily applicable in daily clinical practice that allowed accurate non-invasive measurement of regional metabolic tissue functions in addition to the associated structural characteristics of CT scan. Linear endosonography (EBUS and EUS) has brought a revolutionary novelty in invasive tissue sampling, because it allows in daily clinical practice accurate invasive tissue sampling of lesions and/or lymph nodes all along the central tracheobronchial tree and/or oesophagogastric tract. In this chapter we will discuss the principles and technical aspects of the techniques, as well as indications for diagnosis and TNM staging of lung cancer.

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Correspondence to Christophe Dooms .

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Dooms, C., Deroose, C. (2015). Integrated PET/CT and Linear Endosonography (EBUS and EUS). In: Peters, S., Besse, B. (eds) New Therapeutic Strategies in Lung Cancers. Springer, Cham. https://doi.org/10.1007/978-3-319-06062-0_2

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  • DOI: https://doi.org/10.1007/978-3-319-06062-0_2

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