Abstract
Pancreas transplantation has become accepted as the only definitive long-term treatment that reliably restores euglycemia by restoring endogenous insulin production and improving glucose counterregulation in patients with type 1 diabetes mellitus and in carefully selected patients with insulin-dependent type 2 diabetes mellitus. Despite five decades of experience and with more than 41,000 pancreas transplants performed worldwide through 2011, a multitude of variations exist in operative technique, reflecting the lack of consensus regarding the best method for implanting a pancreas allograft into a recipient. These differences in technique are primarily related to the method of pancreatic exocrine secretion drainage and the site of portal-venous drainage. The surgical technique of pancreas transplantation has evolved over time in response to technical complications and physiologic derangements associated with earlier methods of implantation. This chapter reviews the historical development of the pancreas transplant technique and elaborates on the rationale for the different variations currently practiced. Detailed descriptions of the most common technical approaches to implantation are provided.
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Khan, M.A., Smith, F.R., Rogers, J. (2019). Surgical Technique of Pancreas Transplantation. In: Shah, A., Doria, C., Lim, J. (eds) Contemporary Pancreas and Small Bowel Transplantation . Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-05257-1_2001
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DOI: https://doi.org/10.1007/978-3-319-05257-1_2001
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