Skip to main content

Swern oxidation

  • Chapter
  • First Online:
Name Reactions

Abstract

Oxidation of alcohols to the corresponding carbonyl compounds using (COCl)2, DMSO, and quenching with Et3N.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. (a) Huang, S. L.; Omura, K.; Swern, D. J. Org. Chem. 1976, 41, 3329–3331. (b) Huang, S. L.; Omura, K.; Swern, D. Synthesis 1978, 4, 297–299. (c) Mancuso, A. J.; Huang, S. L.; Swern, D. J. Org. Chem. 1978, 43, 2480–2482. Daniel Swern was a professor at Temple University.

    Google Scholar 

  2. Ghera, E.; Ben-David, Y. J. Org. Chem. 1988, 53, 2972–2979.

    Article  CAS  Google Scholar 

  3. Smith, A. B., III; Leenay, T. L.; Liu, H. J.; Nelson, L. A. K.; Ball, R. G. Tetrahedron Lett. 1988, 29, 49–52.

    Article  CAS  Google Scholar 

  4. Tidwell, T. T. Org. React. 1990, 39, 297–572. (Review).

    Google Scholar 

  5. Chadka, N. K.; Batcho, A. D.; Tang P. C.; Courtney, L. F.; Cook C. M.; Wovliulich, P. M.; Usković, M. R. J. Org. Chem. 1991, 56, 4714–4718.

    Article  Google Scholar 

  6. Harris, J. M.; Liu, Y.; Chai, S.; Andrews, M. D.; Vederas, J. C. J. Org. Chem. 1998, 63, 2407–2409. (Odorless protocols).

    Google Scholar 

  7. Stork, G.; Niu, D.; Fujimoto, R. A.; Koft, E. R.; Bakovec, J. M.; Tata, J. R.; Dake, G. R. J. Am. Chem. Soc. 2001, 123, 3239–3242.

    Article  CAS  Google Scholar 

  8. Nishide, K.; Ohsugi, S.-i.; Fudesaka, M.; Kodama, S.; Node, M. Tetrahedron Lett. 2002, 43, 5177–5179. (Another odorless protocols).

    Google Scholar 

  9. Ahmad, N. M. Swern Oxidation. In Name Reactions for Functional Group Transformations; Li, J. J., Ed.; Wiley: Hoboken, NJ, 2007, pp 291–308. (Review).

    Google Scholar 

  10. Lopez-Alvarado, P; Steinhoff, J; Miranda, S; Avendano, C; Menendez, J. C. Tetrahedron 2009, 65, 1660–1672.

    Google Scholar 

  11. Zanatta, N.; Aquino, E. da C.; da Silva, F. M.; Bonacorso, H. G.; Martins, M. A. P. Synthesis 2012, 44, 3477–3482.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Li, J.J. (2014). Swern oxidation. In: Name Reactions. Springer, Cham. https://doi.org/10.1007/978-3-319-03979-4_270

Download citation

Publish with us

Policies and ethics