Skip to main content

Nef reaction

  • Chapter
  • First Online:
Name Reactions
  • 368 Accesses

Abstract

Conversion of a primary or secondary nitroalkane into the corresponding carbonyl compound.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 79.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Nef, J. U. Ann. 1894, 280, 263––342. John Ulrich Nef (1862–1915) was born in Switzerland and immigrated to the US at the age of four with his parents. He went to Munich, Germany to study with Adolf von Baeyer, earning a Ph.D. In 1886. Back to the States, he served as a professor at Purdue University, Clark University, and the University of Chicago. The Nef reaction was discovered at Clark University in Worcester, Massachusetts. Nef was temperamental and impulsive, suffering from a couple of mental breakdowns. He was also highly individualistic, and had never published with a coworker save for three early articles.

    Google Scholar 

  2. Pinnick, H. W. Org. React. 1990, 38, 655–792. (Review).

    Google Scholar 

  3. Adam, W.; Makosza, M.; Saha-Moeller, C. R.; Zhao, C.-G. Synlett 1998, 1335–1336.

    Google Scholar 

  4. Thominiaux, C.; Rousse, S.; Desmaele, D.; d’Angelo, J.; Riche, C. Tetrahedron: Asymmetry 1999, 10, 2015–2021.

    Article  CAS  Google Scholar 

  5. Capecchi, T.; de Koning, C. B.; Michael, J. P. J. Chem. Soc., Perkin Trans. 1 2000, 2681–2688.

    Google Scholar 

  6. Ballini, R.; Bosica, G.; Fiorini, D.; Petrini, M. Tetrahedron Lett. 2002, 43, 5233–5235.

    Article  CAS  Google Scholar 

  7. Chung, W. K.; Chiu, P. Synlett 2005, 55–58.

    Google Scholar 

  8. Wolfe, J. P. Nef reaction. In Name Reactions for Functional Group Transformations; Li, J. J., Ed.; Wiley: Hoboken, NJ, 2007, pp 645–652. (Review).

    Google Scholar 

  9. Burés, J.; Vilarrasa, J. Tetrahedron Lett. 2008, 49, 441–444.

    Article  Google Scholar 

  10. Felluga, F.; Pitacco, G.; Valentin, E.; Venneri, C. D. Tetrahedron: Asymmetry 2008, 19, 945–955.

    Article  CAS  Google Scholar 

  11. Chinmay Bhat, C.; Tilve, S. G. Tetrahedron 2013, 69, 6129–6143.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Li, J.J. (2014). Nef reaction. In: Name Reactions. Springer, Cham. https://doi.org/10.1007/978-3-319-03979-4_189

Download citation

Publish with us

Policies and ethics