Abstract
Base-promoted aminothiophene formation from ketone, α-active methylene nitrile and elemental sulfur.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
(a) Gewald, K. Z. Chem. 1962, 2, 305–306. (b) Gewald, K.; Schinke, E.; Böttcher, H. Chem. Ber. 1966, 99, 94–100. (c) Gewald, K.; Neumann, G.; Böttcher, H. Z. Chem. 1966, 6, 261. (d) Gewald, K.; Schinke, E. Chem. Ber. 1966, 99, 271–275. Karl Gewald(1930–) is a professor at Technical University of Dresden.
Mayer, R.; Gewald, K. Angew. Chem. Int. Ed. 1967, 6, 294–306. (Review).
Gewald, K. Chimia 1980, 34, 101–110. (Review).
Bacon, E. R.; Daum, S. J. J. Heterocycl. Chem. 1991, 28, 1953-1955.
Sabnis, R. W. Sulfur Reports 1994, 16, 1–17. (Review).
Sabnis, R. W.; Rangnekar, D. W.; Sonawane, N. D. J. Heterocycl. Chem. 1999, 36, 333–345. (Review).
Gütschow, M.; Kuerschner, L.; Neumann, U.; Pietsch, M.; Löser, R.; Koglin, N.; Eger, K. J. Med. Chem. 1999, 42, 5437.
Tinsley, J. M. Gewald Aminothiophene Synthesis. In Name Reactions in Heterocyclic Chemistry; Li, J. J., Ed.; Wiley: Hoboken, NJ, 2005, pp 193–198. (Review).
Barnes, D. M.; Haight, A. R.; Hameury, T.; McLaughlin, M. A.; Mei, J.; Tedrow, J. S.; Dalla Riva Toma, J. Tetrahedron 2006, 62, 11311–11319.
Tormyshev, V. M.; Trukhin, D. V.; Rogozhnikova, O. Yu.; Mikhalina, T. V.; Troitskaya, T. I.; Flinn, A. Synlett 2006, 2559–2564.
Puterová, Z.; Andicsová, A.; Végh, D. Tetrahedron 2008, 64, 11262–11269.
Ma, L.; Yuan, L.; Xu, C.; Li, G.; Tao, M.; Zhang, W. Synthesis 2013, 45, 45–52.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Li, J.J. (2014). Gewald aminothiophene synthesis. In: Name Reactions. Springer, Cham. https://doi.org/10.1007/978-3-319-03979-4_118
Download citation
DOI: https://doi.org/10.1007/978-3-319-03979-4_118
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-03978-7
Online ISBN: 978-3-319-03979-4
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)