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Fungal Endophytes as an Alternative Natural Resource for the Discovery of Bioactive Compounds of Pharmacological Importance

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Endophytic Fungi

Part of the book series: Fungal Biology ((FUNGBIO))

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Abstract

Fungal endophytes are microorganisms that live in symbiotic relationships with the host plant for at least a part of their life cycle. One or more fungal endophytes are present in every plant across the globe. Fungal endophytes have emerged as a potential natural reservoir for bioactive secondary metabolites to meet the never-ending need for effective treatments. Secondary metabolites are divided into a number of classes, including alkaloids, benzopyranones, chinones, flavonoids, phenolic acids, quinones, steroids, saponins, tannins, terpenoids, tetralones, xanthones, etc. Endophytic fungi such as Alternaria sp., Aspergillus sp., Bipolaris sp., Cephalosporium sp., Chaetomium sp., Colletotrichum sp., Emericella sp., Fusarium sp., Guignardia sp., Hormonema sp., Metarhizium sp., Mucor sp., Paecilomyces sp., Penicillium sp., Phomopsis sp., Talaromyces sp., Taxomyces sp., Tolypocladium sp., Xylaria sp., etc. have been reported to possess potential bioactive compounds. Thus, they are potential sources of several natural drugs available in the market for antibacterial, antifungal, antiviral, antioxidant, anti-inflammatory, anticancer, and antidiabetic agents. This chapter summarizes about various fungal endophytes, their association with plants, and the pharmaceutical application of their secondary metabolites.

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Authors and Affiliations

  1. Biological Sciences & Technology Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam, India

    Jyoti Lakshmi Hati Boruah, Parishmita Gogoi, Niraj Kumar, Babli Borah, Maini Borah, Pooja Talukdar, Cecilia Lulu, Priyanka Gogoi, Archana Yadav, Upasana Goswami & Ratul Saikia

  2. Natural Product Chemistry Group, Chemical Sciences and Technology Division, Jorhat, Assam, India

    Deepjyoti Das

  3. AcSIR- Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, India

    Deepjyoti Das, Parishmita Gogoi, Niraj Kumar, Cecilia Lulu, Priyanka Gogoi & Ratul Saikia

  4. Department of Agriculture & Environmental Sciences, National Institute of Food Technology, Entrepreneurship & Management (NIFTEM), Sonipat, Haryana, India

    Bhim P. Singh

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  1. Jyoti Lakshmi Hati Boruah
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  2. Deepjyoti Das
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  3. Parishmita Gogoi
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  4. Niraj Kumar
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  5. Babli Borah
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  8. Cecilia Lulu
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  9. Priyanka Gogoi
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  10. Archana Yadav
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  11. Upasana Goswami
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  12. Bhim P. Singh
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  13. Ratul Saikia
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Corresponding author

Correspondence to Ratul Saikia .

Editor information

Editors and Affiliations

  1. Department of Agriculture and Environmental Sciences, National Institute of Food Technology Entrepreneurship and Management (NIFTEM), Sonipat, Haryana, India

    Bhim Pratap Singh

  2. Botany and Microbiology Department Faculty of Science, Suez Canal University, Ismailia, Egypt

    Ahmed M. Abdel-Azeem

  3. Centre of Experimental Medicine and Surgery Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    Vibhav Gautam

  4. Department of BotanyPachhunga University College, Mizoram University, Mizoram, India

    Garima Singh

  5. Centre of Experimental Medicine and Surgery Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    Santosh Kumar Singh

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Boruah, J.L.H. et al. (2024). Fungal Endophytes as an Alternative Natural Resource for the Discovery of Bioactive Compounds of Pharmacological Importance. In: Singh, B.P., Abdel-Azeem, A.M., Gautam, V., Singh, G., Singh, S.K. (eds) Endophytic Fungi. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-031-49112-2_3

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