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Ocular Biomechanics of Glaucoma

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XLVI Mexican Conference on Biomedical Engineering (CNIB 2023)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 97))

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Abstract

In this study, deformations, and principal stresses in ocular tissues, especially in the optic disc, under glaucoma conditions were investigated. Four models with different parameters were developed, and their results were compared. Although the models did not yield quantitatively similar results, critical areas in the tissues were found. In these result values, the possibility of the presence of glaucoma exists, contributing to the early detection of this disease. Deformation in ocular tissues and an increase in principal stresses in the optic disc under glaucoma conditions were demonstrated. This indicates that optic nerve cells lose their mechanical properties due to the presence of stress concentrators, affecting cellular nutrition and potentially leading to cell death over time. Despite the quantitative differences, the models shared critical areas due to the geometry of the eye. These findings expand the understanding of the effects of glaucoma on ocular tissues.

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Acknowledgments

This project owes its success to the invaluable assistance provided by Alicia Natalia Ruíz Ramos for her collaboration in the research and contribution to the design of the four models used in this study. We are deeply grateful to her.

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Authors and Affiliations

  1. Universidad de Guanajuato División de Ingeniería Campus Irapuato Salamanca, Carretera Salamanca-Valle de Santiago Km 3.5+1.8 Comunidad de Palo Blanco, 36885, Salamanca, Guanajuato, México

    Yael Osmar Bravo Sustaita, Ximena Berenice Guzmán González & A. Vidal-Lesso

Authors
  1. Yael Osmar Bravo Sustaita
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  2. Ximena Berenice Guzmán González
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  3. A. Vidal-Lesso
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Corresponding author

Correspondence to A. Vidal-Lesso .

Editor information

Editors and Affiliations

  1. División de Estudios de Posgrado e Investigación, Instituto Tecnológico de Orizaba, Orizaba, Mexico

    José de Jesús Agustín Flores Cuautle

  2. Department of Biomedical Engineering, University of California, Irvine, Irvine, CA, USA

    Balam Benítez-Mata

  3. Departamento de Bioingeniería Traslacional, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

    Ricardo Antonio Salido-Ruiz

  4. Facultad de Ingeniería, Universidad Autónoma de Guerrero, Chilpancingo de los Bravo, Guerrero, Mexico

    Gustavo Adolfo Alonso-Silverio

  5. Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico

    Guadalupe Dorantes-Méndez

  6. Departamento de Ingeniería Eléctrica y Computación, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chihuahua, Mexico

    Esmeralda Zúñiga-Aguilar

  7. Departamento de Bioingeniería Traslacional, Universidad de Guadalajara, Guadalajara, Mexico

    Hugo A. Vélez-Pérez

  8. Facultad de Medicina, Universidad Autónoma del Estado de México, Toluca de Lerdo, Mexico

    Edgar Del Hierro-Gutiérrez

  9. Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico

    Aldo Rodrigo Mejía-Rodríguez

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Sustaita, Y.O.B., González, X.B.G., Vidal-Lesso, A. (2024). Ocular Biomechanics of Glaucoma. In: Flores Cuautle, J.d.J.A., et al. XLVI Mexican Conference on Biomedical Engineering. CNIB 2023. IFMBE Proceedings, vol 97. Springer, Cham. https://doi.org/10.1007/978-3-031-46936-7_6

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  • DOI: https://doi.org/10.1007/978-3-031-46936-7_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-46935-0

  • Online ISBN: 978-3-031-46936-7

  • eBook Packages: EngineeringEngineering (R0)

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