Abstract
Prescription demand and the complexity of patients’ pharmaceutical protocols have significantly increased during the last decade. To achieve greater effectiveness of the overall prescription fulfillment process, the development and deployment of modern pharmacy automation systems, known as mail order pharmacy (MOP) or central fill pharmacy (CFP) systems, have been accelerated in recent years. Such advanced systems adopted automated robotic dispensing systems (RDS) and collation systems that can prepare more than tens of thousands of prescriptions per day. Designing and operating large-scale pharmacy systems are very complicated and expensive to ensure their expected throughputs and patient safety consideration. Therefore, a thorough system evaluation and investigation for potential improvement regarding the performance and operational efficiency should be conducted. This chapter aims to provide the detailed working mechanisms of pharmacy automation systems and introduce five important optimization problems in pharmacy automation, which include the RDS planogram design optimization, RDS replenishment optimization, collation system analysis, order scheduling optimization, and pharmacy database mining. To better demonstrate the optimization modeling in the context of pharmacy automation, a case study of the RDS replenishment process optimization based on modeling and simulation approaches is presented. The chapter also provides several research and development directions, which can potentially facilitate the realization of smart pharmacy automation solutions in the era of Industrial 4.0.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Conti, R.M., Turner, A., Hughes-Cromwick, P.: Projections of US prescription drug spending and key policy implications. JAMA Health Forum 2(1), e201613 (2021). https://doi.org/10.1001/jamahealthforum.2020.1613
U.S. prescription drug spending as high as $610 billion by 2021: report. https://www.reuters.com/article/us-usa-drugspending-quintilesims/u-s-prescription-drug-spending-as-high-as-610-billion-by-2021-report-idUSKBN1800BU
WHO: World Health Organization. (2019). Coronavirus disease (COVID-19) outbreak situation
Ayati, N., Saiyarsarai, P., Nikfar, S.: Short and long term impacts of COVID-19 on the pharmaceutical sector. DARU J. Pharmace. Sci. 28(2), 799–805 (2020)
Yang, Y.: Threshold-and Priority-Based Dispatching Rule in Mail-Order Pharmacy Automation Systems (Doctoral dissertation, State University of New York at Binghamton) (2021)
Khader, N.: Frequent pattern mining in a pharmacy database through the use of Hadoop. State University of New York at Binghamton (2014)
Angelo, L.B., Christensen, D.B., Ferreri, S.P.: Impact of community pharmacy automation on workflow, workload, and patient interaction. J. American Pharmac. Ass. JAPhA 45(2), 138–144 (2005)
Tan, W.S., Chua, S.L., Yong, K.W., Wu, T.S.: Impact of pharmacy automation on patient waiting time: An application of computer simulation. Annals Academy of Medicine Singapore 38(6), 501 (2009)
Beard, R.J., Smith, P.: Integrated electronic prescribing and robotic dispensing: a case study. Springerplus 2(1), 1–7 (2013)
Shaya, F.T., Eddington, N.D.: Disruptive innovation in pharmacy: Lessons from the amazon frontier. In: JAMA Health Forum, vol. 1 (American Medical Association, 2020), pp. e200, 038–e200, 038 (2020)
Sundaramurthy, S.S.: Mining Frequent Itemsets of a Central Fill Pharmacy Transaction Database to Enhance the Planogram of Robotic Dispensing System (Doctoral dissertation, State University of New York at Binghamton) (2018)
O'Connor, R.: Minimizing Replenishment Cost in a Central Fill Pharmacy Using a Markov Chain (Doctoral dissertation, State University of New York at Binghamton) (2020)
Li, D., Yoon, S.W.: A novel fill-time window minimisation problem and adaptive parallel tabu search algorithm in mail-order pharmacy automation system. Int. J. Prod. Res. 53(14), 4189–4205 (2015)
Wang, H., Yoon, S.W.: Drug dispenser replenishment optimization via mixed integer programming in central fill pharmacy systems. In: 2016 Industrial and Systems Engineering Research Conference, ISERC 2016 (2016)
Li, Y., Zhang, Q., Yoon, S.W.: Discrete event simulation-based collation system analysis in mail-order pharmacy automation system. In: IIE Annual Conference. Proceedings, pp. 828–833. Institute of Industrial and Systems Engineers (IISE) (2019)
Leading-edge pharmacy automation solutions. Retrieved September 18, 2022, from: https://iarx.com/
Wang, H., Dauod, H., Khader, N., Yoon, S.W., Srihari, K.: Multi-objective parallel robotic dispensing planogram optimisation using association rule mining and evolutionary algorithms. Int. J. Comput. Integr. Manuf. 31(8), 799–814 (2018)
Khader, N., Lashier, A., Yoon, S.W.: Pharmacy robotic dispensing and planogram analysis using association rule mining with prescription data. Expert Syst. Appl. 57, 296–310 (2016). https://doi.org/10.1016/j.eswa.2016.02.045
Hansen, J.M., Raut, S., Swami, S.: Retail shelf allocation: a comparative analysis of heuristic and meta-heuristic approaches. J. Retail. 86(1), 94–105 (2010). https://doi.org/10.1016/j.jretai.2010.01.004
Dauod, H., Serhan, D., Wang, H., Khader, N., Yoon, S.W., Srihari, K.: Robust receding horizon control strategy for replenishment planning of pharmacy robotic dispensing systems. Robo. Comp.-Integr. Manuf. 59, 177–188 (2019). https://doi.org/10.1016/j.rcim.2019.04.001
Dauod, H., Wang, H., Khader, N., Yoon, S.W., Srihari, K.: Real-time dispenser replenishment optimization based on receding horizon control. Procedia Manufacturing 11, 1782–1789 (2017). https://doi.org/10.1016/j.promfg.2017.07.313
O’Connor, R., Yoon, S.W., Kwon, S.: Analysis and optimization of replenishment process for robotic dispensing system in a central fill pharmacy. Comp. Two Collartio Ind. Eng. 154, 107116 (2021). https://doi.org/10.1016/j.cie.2021.107116
Alhaag, M.H., Aziz, T., Alharkan, I.M.: A queuing model for health care pharmacy using software Arena. In: 2015 International Conference on Industrial Engineering and Operations Management, IEEE 2015, pp. 1–11 (2015)
Mei, K., Li, D., Yoon, S.W., Ryu, J.H.: Multi-objective optimization of collation delay and makespan in mail-order pharmacy automated distribution system. The Int. J. Adv. Manuf. Technol. 83(14), 475–488 (2016)
Li, D., Yoon, S.W.: Simulation Based MANOVA Analysis of Pharmaceutical Automation System in Central Fill Pharmacy. IEEE InternationalConference on Industrial Engineering and Engineering Management, pp. 1647–1651 (Dec. 2012)
Wang, H., Yoon, S.W.: Evaluation and optimization of automatic drug dispensing/filling system. Proceedings of the 3rd Annual World Conference of the Society for Industrial and Systems Engineering (2014)
Wang, H., Serhan, D.M., Yoon, S.W.: Collation delay optimization using discrete event simulation in mail-order pharmacy automation systems. In: Proceedings of the 2016 Industrial and Systems Engineering Research Conference (2016)
Dauod, H., Li, D., Yoon, S.W., Srihari, K.: Multi-objective optimization of the order scheduling problem in mail-order pharmacy automation systems. The Int. J. Advan. Manuf. Technol. 1–11 (2016)
Acknowledgements
This study was supported by the Watson Institute of Systems Excellence (WISE) at Binghamton University and by iA. The authors would like to thank the anonymous reviews for their valuable comments in improving the quality of this manuscript.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this paper
Cite this paper
Cao, N., Alattar, M.S., Jin, Y., Kwon, S., Yoon, S.W. (2023). Optimization in Pharmacy Automation System. In: Huang, CY., Yoon, S.W. (eds) Systems Collaboration and Integration. ICPR1 2021. Automation, Collaboration, & E-Services, vol 14. Springer, Cham. https://doi.org/10.1007/978-3-031-44373-2_19
Download citation
DOI: https://doi.org/10.1007/978-3-031-44373-2_19
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-44372-5
Online ISBN: 978-3-031-44373-2
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)