Abstract
In this chapter cytologic features of brain tissue and cerebrospinal fluid (CSF) in normal and non-neoplastic conditions are described, characterization of possible contamination elements is presented, and differential diagnosis is discussed. We present the review of cytologic features of both brain tissue (used primarily by neuropathologists for intraoperative consultation with major purpose to answer questions required for directing surgery and immediate treatment) and CSF (used for diagnosis and posttreatment monitoring of wide range of nonneoplastic and neoplastic conditions).
Importance of intraoperative cytopathologic evaluation of brain tissue, advantages and disadvantages, types of cytologic preparations, normal cytology and potential misinterpretation as abnormalities are discussed in the first part of the chapter.
CSF cytology is the focus of the second part of the chapter: clinical indication of CSF evaluation, CSF collection, macroscopic and microscopic features of CSF in normal and benign conditions, extracranial and extraspinal elements/contaminants are reviewed.
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Darbinyan, A., Huttner, A., Wang, M. (2023). Brain and Cerebrospinal Fluid. In: Gilani, S.M., Cai, G. (eds) Non-Neoplastic Cytology. Springer, Cham. https://doi.org/10.1007/978-3-031-44289-6_18
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DOI: https://doi.org/10.1007/978-3-031-44289-6_18
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