Abstract
Atrioventricular conduction abnormalities are the most common presentation of early disseminated Lyme carditis. Up to two-thirds of patients with Lyme carditis will progress to a high-degree atrioventricular block; however, it can reverse completely when early antibiotic treatment is provided. A systematic approach to early disseminated Lyme carditis is essential since the identification of Lyme as the etiology in patients with heart block will avoid the unnecessary implantation of permanent pacemakers. This chapter covers the clinical manifestation of early disseminated Lyme carditis.
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References
Yeung C, Baranchuk A. Diagnosis and treatment of Lyme Carditis: JACC review topic of the week. J Am Coll Cardiol. 2019;73(6):717–26.
Centers for Disease Control and Prevention. Lyme disease: data and surveillance. 2022 [cited 2022 Nov 11]. Available from: www.cdc.gov/lyme/stats/index.html.
Public Health Agency of Canada. Surveillance of Lyme disease. 2022 [cited 2022 Nov 11]. Available from: https://www.canada.ca/en/public-health/services/diseases/lyme-disease/surveillance-lyme-disease.html.
Ripoche M, Gasmi S, Adam-Poupart A, Koffi JK, Lindsay LR, Ludwig A, et al. Passive tick surveillance provides an accurate early signal of emerging Lyme disease risk and human cases in Southern Canada. J Med Entomol. 2018;55(4):1016–26.
Shen RV, McCarthy CA, Smith RP. Lyme Carditis in hospitalized children and adults, a case series. Open Forum Infect Dis. 2021;8(7):ofab140.
Robinson ML, Kobayashi T, Higgins Y, Calkins H, Melia MT. Lyme carditis. Infect Dis Clin North Am. 2015;29(2):255–68.
Montgomery RR, Booth CJ, Wang X, Blaho VA, Malawista SE, Brown CR. Recruitment of macrophages and polymorphonuclear leukocytes in Lyme carditis. Infect Immun. 2007;75(2):613–20.
Raveche ES, Schutzer SE, Fernandes H, Bateman H, McCarthy BA, Nickell SP, et al. Evidence of Borrelia autoimmunity-induced component of Lyme carditis and arthritis. J Clin Microbiol. 2005;43(2):850–6.
Krause PJ, Bockenstedt LK. Cardiology patient pages. Lyme disease and the heart. Circulation. 2013;127(7):e451–4.
Uzomah UA, Rozen G, Mohammadreza Hosseini S, Shaqdan A, Ledesma PA, Yu X, et al. Incidence of carditis and predictors of pacemaker implantation in patients hospitalized with Lyme disease. PLoS ONE. 2021;16(11):e0259123.
van der Linde MR. Lyme carditis: clinical characteristics of 105 cases. Scand J Infect Dis Suppl. 1991;77:81–4.
Wang CN, Yeung C, Enriquez A, Chacko S, Hanson S, Redfearn D, et al. Long-term outcomes in treated Lyme Carditis. Curr Probl Cardiol. 2022;47(10):100939.
Fatima B, Sohail MR, Schaff HV. Lyme disease-an unusual cause of a mitral valve endocarditis. Mayo Clin Proc Innov Qual Outcomes. 2018;2(4):398–401.
Duray PH. Histopathology of clinical phases of human Lyme disease. Rheum Dis Clin North Am. 1989;15(4):691–710.
Besant G, Wan D, Yeung C, Blakely C, Branscombe P, Suarez-Fuster L, et al. Suspicious index in Lyme carditis: systematic review and proposed new risk score. Clin Cardiol. 2018;41(12):1611–6.
Yeung C, Baranchuk A. Systematic approach to the diagnosis and treatment of Lyme Carditis and high-degree atrioventricular block. Healthcare (Basel). 2018;6(4).
Munk PS, Orn S, Larsen AI. Lyme carditis: persistent local delayed enhancement by cardiac magnetic resonance imaging. Int J Cardiol. 2007;115(3):e108–10.
Stanek G, Wormser GP, Gray J, Strle F. Lyme borreliosis. Lancet. 2012;379(9814):461–73.
Motamed M, Liblik K, Miranda-Arboleda AF, Wamboldt R, Wang CN, Cingolani O, et al. Disseminated Lyme disease and dilated cardiomyopathy: a systematic review. Trends Cardiovasc Med. 2022.
Wamboldt R, Wang CN, Miller JC, Enriquez A, Yeung C, Chacko S, et al. Pacemaker explanation in patients with Lyme Carditis. JACC Case Rep. 2022;4(10):613–6.
Muehlenbachs A, Bollweg BC, Schulz TJ, Forrester JD, DeLeon CM, Molins C, et al. Cardiac tropism of Borrelia burgdorferi: an autopsy study of sudden cardiac death associated with Lyme Carditis. Am J Pathol. 2016;186(5):1195–205.
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Miranda-Arboleda, A.F., Sierra-David, J.G., Wamboldt, R., Baranchuk, A. (2023). Clinical Manifestations of Early Disseminated Lyme Carditis. In: Baranchuk, A., Wamboldt, R., Wang, C.N. (eds) Lyme Carditis. Springer, Cham. https://doi.org/10.1007/978-3-031-41169-4_6
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DOI: https://doi.org/10.1007/978-3-031-41169-4_6
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