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Depression and Anxiety in Women with Coronary Artery Disease: Prevalence and Links to Adverse Cardiac Outcomes

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Biology of Women’s Heart Health

Part of the book series: Advances in Biochemistry in Health and Disease ((ABHD,volume 26))

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Abstract

Depression and anxiety are highly prevalent among patients with coronary artery disease. Symptoms can severely inhibit patients’ recovery and potentially lead to adverse cardiac-related outcomes, including repeat hospitalizations, recurrent cardiac events, and cardiac-related mortality. Across existing meta-analyses and systematic reviews on the prognostic effects of depression and anxiety on cardiac outcomes, women comprise only a small subset of the population and sex and gender-based analyses are rarely conducted. This is problematic as rates of depression and anxiety post cardiac event are nearly two-times higher in women than men. This chapter will profile recent advances in research on sex differences in the prevalence and prognostic effects of depression and anxiety on adverse cardiac outcomes. Recommendations for improving the identification and appropriate management of women with comorbid coronary artery disease and depression and/or anxiety are proposed.

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  1. Division of Cardiac Prevention and Rehabilitation, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y4W7, Canada

    Karen Bouchard, Alexandra Chiarelli, Michael Dans & Heather Tulloch

  2. University of Ottawa, Ottawa, Canada

    Karen Bouchard & Heather Tulloch

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  1. The Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada

    Lorrie Kirshenbaum

  2. The Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada

    Inna Rabinovich-Nikitin

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Bouchard, K., Chiarelli, A., Dans, M., Tulloch, H. (2023). Depression and Anxiety in Women with Coronary Artery Disease: Prevalence and Links to Adverse Cardiac Outcomes. In: Kirshenbaum, L., Rabinovich-Nikitin, I. (eds) Biology of Women’s Heart Health. Advances in Biochemistry in Health and Disease, vol 26. Springer, Cham. https://doi.org/10.1007/978-3-031-39928-2_19

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