Abstract
In association with biomedical optics, Biophotonics contributes to the field of health sciences through the development of optical methods for early disease diagnosis and monitoring, as well as assessing the effects of different therapies. Such methods are based on the knowledge of interactions between light and biological tissues, enabling the detection, quantification, and correlation of tissue abnormalities with several processes. Optical techniques have advantages, including the use of nonionizing radiation, fast and real-time detection of disease stages, imaging capabilities, and high sensitivity and specificity. Still, these techniques are noninvasive, providing comfort to the patients. In this chapter, the main optical techniques used for the early diagnosis of dental hard tissue pathologies will be presented, with emphasis on the demineralization of enamel and dentin, which is a common characteristic of caries and erosion lesions. Fluorescence imaging or spectroscopy techniques, Fourier transform infrared spectroscopy, Raman spectroscopy, optical coherence tomography, and transillumination are advantageous for these lesions. These methods present high resolution and allow the quantification of optical parameters that may be related to the disease progression. Some techniques are already in clinical use, while others are in broad scientific development, and very close to clinical reality.
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Funding Declaration/Acknowledgments
The authors would like to thank to FAPESP (2017/21887-4), CAPES (PROCAD-CAPES 88881.068505/2014-01) and CNPq (INCT # 465763/2014-6 – Photonics National Institute for Science and Technology – INFO – and 440228/2021-2 National System of Photonics Laboratories – Sisfoton-MCTI).
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da Ana, P.A., Prates, I.T.K., Benetti, C., Del-Valle, M. (2023). Optical Techniques for the Diagnosis and Monitoring of Oral Hard Tissue Lesions. In: Lombello, C.B., da Ana, P.A. (eds) Current Trends in Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-031-38743-2_12
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