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Oral Management of the Chemotherapy Patient

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Dental Science for the Medical Professional

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Abstract

Oral complications from cancer therapy are common and encompass a variety of toxicities affecting the jaw bones, the oral mucosa, and salivary glands. These depend on the cancer type and stage, chemotherapy used, the oral health status, and other comorbidities. The oral complications secondary to chemotherapy lead to prolonged hospital stays, use of analgesics and antibiotics, hospitalizations for pain management, and increased costs. Dentists and dental specialists play a role in cancer patient care before, during, and after treatment. The goal of this chapter is to provide a general overview on the most common oral complications secondary to chemotherapy including immune checkpoint inhibitors.

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References

  1. Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2021. CA Cancer J Clin. 2021;71(1):7–33.

    Article  PubMed  Google Scholar 

  2. Sroussi HY, Epstein JB, Bensadoun R-J, Saunders DP, Lalla RV, Migliorati CA, et al. Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis. Cancer Med. 2017;6(12):2918–31.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Villa A, Sonis S. Toxicities associated with head and neck cancer treatment and oncology-related clinical trials. Curr Probl Cancer. 2016;40(5-6):244–57.

    Article  PubMed  Google Scholar 

  4. Choi SE, Choudhary A, Sonis S, Villa A. Benefits of the involvement of dentists in managing oral complications among patients with oral cavity and oropharyngeal cancer: an analysis of claims data. JCO Oncol Pract. 2021;17:e1668.

    Article  PubMed  Google Scholar 

  5. Epstein JB, Güneri P, Barasch A. Appropriate and necessary oral care for people with cancer: guidance to obtain the right oral and dental care at the right time. Support Care Cancer. 2014;22(7):1981–8.

    Article  PubMed  Google Scholar 

  6. Woo S-B. Oral epithelial dysplasia and premalignancy. Head Neck Pathol. 2019;13(3):423–39.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Brennan MT, Woo S-B, Lockhart PB. Dental treatment planning and management in the patient who has cancer. Dent Clin North Am. 2008;52(1):19–37, vii. eng.

    Article  PubMed  Google Scholar 

  8. Levi LE, Lalla RV. Dental treatment planning for the patient with oral cancer. Dent Clin North Am. 2018;62(1):121–30.

    Article  PubMed  Google Scholar 

  9. Oral complications of chemotherapy and head/neck radiation (PDQ(R)): health professional version. PDQ cancer information summaries. Bethesda, MD. 2002.

    Google Scholar 

  10. Sultan AS, Kong EF, Rizk AM, Jabra-Rizk MA. The oral microbiome: a lesson in coexistence. PLoS Pathog. 2018;14(1):e1006719; PubMed PMID: 29370304. PMCID: PMC5784999. Epub 2018/01/25. eng.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Vila T, Sultan AS, Montelongo-Jauregui D, Jabra-Rizk MA. Oral candidiasis: a disease of opportunity. J Fungi (Basel). 2020;6(1):15; PubMed PMID: 31963180. Epub 2020/01/16. eng.

    Article  CAS  PubMed  Google Scholar 

  12. Vila T, Rizk AM, Sultan AS, Jabra-Rizk MA. The power of saliva: antimicrobial and beyond. PLoS Pathog. 2019;15(11):e1008058; PubMed PMID: 31725797. PMCID: PMC6855406. Epub 20191114. eng.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Palmason S, Marty FM, Treister NS. How do we manage oral infections in allogeneic stem cell transplantation and other severely immunocompromised patients? Oral Maxillofac Surg Clin North Am. 2011;23(4):579–99, vii. PubMed PMID: 21982611. eng.

    Article  PubMed  Google Scholar 

  14. Villa A, Sonis ST. An update on pharmacotherapies in active development for the management of cancer regimen-associated oral mucositis. Expert Opin Pharmacother. 2020;21(5):541–8. PubMed PMID: 31990597. Epub 20200128. eng.

    Article  CAS  PubMed  Google Scholar 

  15. Sankaran SP, Villa A, Sonis S. Healthcare-associated infections among patients hospitalized for cancers of the lip, oral cavity and pharynx. Infect Prev Pract. 2021;3(1):100115; PubMed PMID: 34368735. PMCID: PMC8336044. Epub 20210113. eng.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Graber CJ, de Almeida KN, Atkinson JC, Javaheri D, Fukuda CD, Gill VJ, et al. Dental health and viridans streptococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplant. 2001;27(5):537–42; PubMed PMID: 11313689. eng.

    Article  CAS  PubMed  Google Scholar 

  17. Sultan AS, Zimering Y, Petruzziello G, Alyea EP, Antin JH, Soiffer RJ, et al. Oral health status and risk of bacteremia following allogeneic hematopoietic cell transplantation. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;124(3):253–60. PubMed PMID: 28823316. Epub 20170616. eng.

    Article  PubMed  Google Scholar 

  18. Schmalz G, Tulani L, Busjan R, Haak R, Kottmann T, Trümper L, et al. Dental and periodontal treatment need after dental clearance is not associated with the outcome of induction therapy in patients with acute leukemia: results of a retrospective pilot study. Adv Hematol. 2020;2020:6710906. PubMed PMID: 32373173. PMCID: PMC7191429. Epub 20200421. eng.

    PubMed  PubMed Central  Google Scholar 

  19. Mawardi H, Treister N, Felemban O, Alamoudi W, Algohary G, Alsultan A, et al. Current practice of oral care for hematopoietic stem cell transplant patients: a survey of the eastern mediterranean blood and marrow transplantation group. Hematol Oncol Stem Cell Ther. 2021;16:42. PubMed PMID: 33631114. Epub 20210211. eng.

    Google Scholar 

  20. Spijkervet FKL, Schuurhuis JM, Stokman MA, Witjes MJH, Vissink A. Should oral foci of infection be removed before the onset of radiotherapy or chemotherapy? Oral Dis. 2021;27(1):7–13. PubMed PMID: 32166855. PMCID: PMC7818265. Epub 20200601. eng.

    Article  PubMed  Google Scholar 

  21. Elad S, Raber-Durlacher JE, Brennan MT, Saunders DP, Mank AP, Zadik Y, et al. Basic oral care for hematology-oncology patients and hematopoietic stem cell transplantation recipients: a position paper from the joint task force of the multinational Association of Supportive Care in cancer/International Society of Oral Oncology (MASCC/ISOO) and the European Society for Blood and Marrow Transplantation (EBMT). Support Care Cancer. 2015;23(1):223–36. PubMed PMID: 25189149. PMCID: PMC4328129. eng.

    Article  PubMed  Google Scholar 

  22. Walsh LJ. Clinical assessment and management of the oral environment in the oncology patient. Aust Dent J. 2010;55(Suppl 1):66–77. PubMed PMID: 20553247. eng.

    Article  PubMed  Google Scholar 

  23. Hansen HJ, Estilo C, Owosho A, Solano AK, Randazzo J, Huryn J, et al. Dental status and risk of odontogenic complication in patients undergoing hematopoietic stem cell transplant. Support Care Cancer. 2021;29(4):2231–8. PubMed PMID: 32901321. Epub 20200908. eng.

    Article  PubMed  Google Scholar 

  24. Das P, Challacombe SJ. Dry mouth and clinical oral dryness scoring systems. Prim Dent J. 2016;5(1):77–9. PubMed PMID: 29029657. eng.

    Article  PubMed  Google Scholar 

  25. Scully C, Bagan JV. Adverse drug reactions in the orofacial region. Crit Rev Oral Biol Med. 2004;15(4):221–39. PubMed PMID: 15284187. Epub 20040701. eng.

    Article  CAS  PubMed  Google Scholar 

  26. Yuan A, Woo SB. Adverse drug events in the oral cavity. Dermatol Clin. 2020;38(4):523–33. PubMed PMID: 32892860. Epub 20200811. eng.

    Article  CAS  PubMed  Google Scholar 

  27. Yuan A, Woo SB. Adverse drug events in the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;119(1):35–47. PubMed PMID: 25442252. Epub 20140917. eng.

    Article  PubMed  Google Scholar 

  28. Osailan SM, Pramanik R, Shirlaw P, Proctor GB, Challacombe SJ. Clinical assessment of oral dryness: development of a scoring system related to salivary flow and mucosal wetness. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(5):597–603. PubMed PMID: 22959491. Epub 20120907. eng.

    Article  CAS  PubMed  Google Scholar 

  29. Osailan S, Pramanik R, Shirodaria S, Challacombe SJ, Proctor GB. Investigating the relationship between hyposalivation and mucosal wetness. Oral Dis. 2011;17(1):109–14. PubMed PMID: 21029258. Epub 20101028. eng.

    Article  CAS  PubMed  Google Scholar 

  30. Furness S, Worthington HV, Bryan G, Birchenough S, McMillan R. Interventions for the management of dry mouth: topical therapies. Cochrane Database Syst Rev. 2011;12:CD008934. PubMed PMID: 22161442. Epub 20111207. eng.

    Google Scholar 

  31. Villa A, Sonis ST. Mucositis: pathobiology and management. Curr Opin Oncol. 2015;27(3):159–64. PubMed PMID: 25774860. eng.

    Article  CAS  PubMed  Google Scholar 

  32. Vasconcelos RM, Sanfilippo N, Paster BJ, Kerr AR, Li Y, Ramalho L, et al. Host-microbiome cross-talk in oral mucositis. J Dent Res. 2016;95(7):725–33. PubMed PMID: 27053118. PMCID: PMC4914867. Epub 20160406. eng, 725.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  33. Sonis ST. The pathobiology of mucositis. Nat Rev Cancer. 2004;4(4):277–84. PubMed PMID: 15057287. eng.

    Article  CAS  PubMed  Google Scholar 

  34. Elad S, Cheng KKF, Lalla RV, Yarom N, Hong C, Logan RM, et al. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2020;126(19):4423–31. PubMed PMID: 32786044. PMCID: PMC7540329. Epub 20200728. eng.

    Article  PubMed  Google Scholar 

  35. Dysgeusia Section OCSGMAoSCiCISoOO, Hovan AJ, Williams PM, Stevenson-Moore P, Wahlin YB, KEO O, et al. A systematic review of dysgeusia induced by cancer therapies. Support Care Cancer. 2010;18(8):1081–7. en, 1081.

    Article  Google Scholar 

  36. Amézaga J, Alfaro B, Ríos Y, Larraioz A, Ugartemendia G, Urruticoechea A, et al. Assessing taste and smell alterations in cancer patients undergoing chemotherapy according to treatment. Support Care Cancer. 2018;26(12):4077–86. en, 4077.

    Article  PubMed  Google Scholar 

  37. Wong HM. Oral complications and management strategies for patients undergoing cancer therapy. Sci World J. 2014;2014:1–14. en.

    Google Scholar 

  38. Jensen SB, Mouridsen HT, Bergmann OJ, Reibel J, Brünner N, Nauntofte B. Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(2):217–26. eng, 217.

    Article  PubMed  Google Scholar 

  39. Gamper E-M, Giesinger JM, Oberguggenberger A, Kemmler G, Wintner LM, Gattringer K, et al. Taste alterations in breast and gynaecological cancer patients receiving chemotherapy: prevalence, course of severity, and quality of life correlates. Acta Oncol. 2012;51(4):490–6. eng, 490.

    Article  CAS  PubMed  Google Scholar 

  40. Fink M. Vitamin D deficiency is a cofactor of chemotherapy-induced mucocutaneous toxicity and dysgeusia. J Clin Oncol. 2011;29(4):e81–2. eng, e81.

    Article  PubMed  Google Scholar 

  41. Yamagata T, Nakamura Y, Yamagata Y, Nakanishi M, Matsunaga K, Nakanishi H, et al. The pilot trial of the prevention of the increase in electrical taste thresholds by zinc containing fluid infusion during chemotherapy to treat primary lung cancer. J Exp Clin Cancer Res. 2003;22(4):557–63. eng.

    CAS  PubMed  Google Scholar 

  42. Edelman MJ, Gandara DR, Meyers FJ, Ishii R, O’Mahony M, Uhrich M, et al. Serotonergic blockade in the treatment of the cancer anorexia-cachexia syndrome. Cancer. 1999;86(4):684–8. eng, 684.

    Article  CAS  PubMed  Google Scholar 

  43. Heckmann SM, Kirchner E, Grushka M, Wichmann MG, Hummel T. A double-blind study on clonazepam in patients with burning mouth syndrome. Laryngoscope. 2012;122(4):813–6. eng, 813.

    Article  CAS  PubMed  Google Scholar 

  44. Brisbois TD, de Kock IH, Watanabe SM, Mirhosseini M, Lamoureux DC, Chasen M, et al. Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial. Ann Oncol. 2011;22(9):2086–93. eng, 2086.

    Article  CAS  PubMed  Google Scholar 

  45. Murtaza B, Hichami A, Khan AS, Ghiringhelli F, Khan NA. Alteration in taste perception in cancer: causes and strategies of treatment. Front Physiol. 2017;8:134.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Seretny M, Currie GL, Sena ES, Ramnarine S, Grant R, MacLeod MR, et al. Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis. Pain. 2014;155(12):2461–70. en, 2461.

    Article  PubMed  Google Scholar 

  47. Argyriou AA, Kyritsis AP, Makatsoris T, Kalofonos HP. Chemotherapy-induced peripheral neuropathy in adults: a comprehensive update of the literature. Cancer Manag Res. 2014;2014(6):135–47. eng.

    Article  Google Scholar 

  48. Ling J, Erol F, Viatchenko-Karpinski V, Kanda H, Gu JG. Orofacial neuropathic pain induced by oxaliplatin: downregulation of KCNQ2 channels in V2 trigeminal ganglion neurons and treatment by the KCNQ2 channel potentiator retigabine. Mol Pain. 2017;13:174480691772471. en.

    Article  Google Scholar 

  49. Vadalouca A, Raptis E, Moka E, Zis P, Sykioti P, Siafaka I. Pharmacological treatment of neuropathic cancer pain: a comprehensive review of the current literature: neuropathic cancer pain pharmacotherapy. Pain Pract. 2012;12(3):219–51. en, 219.

    Article  PubMed  Google Scholar 

  50. Benoliel R, Epstein J, Eliav E, Jurevic R, Elad S. Orofacial pain in cancer: part I—mechanisms. J Dent Res. 2007;86(6):491–505. eng, 491.

    Article  CAS  PubMed  Google Scholar 

  51. Hou S, Huh B, Kim HK, Kim K-H, Abdi S. Treatment of chemotherapy-induced peripheral neuropathy: systematic review and recommendations. Pain Physician. 2018;21(6):571–92. eng, 571.

    PubMed  Google Scholar 

  52. Lee WJ, Lee JL, Chang SE, Lee MW, Kang YK, Choi JH, et al. Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. Br J Dermatol. 2009;161(5):1045–51. PubMed PMID: 19558553. Epub 20090505. eng.

    Article  CAS  PubMed  Google Scholar 

  53. Shawver LK, Slamon D, Ullrich A. Smart drugs: tyrosine kinase inhibitors in cancer therapy. Cancer Cell. 2002;1(2):117–23. PubMed PMID: 12086869. eng.

    Article  CAS  PubMed  Google Scholar 

  54. Arora A, Scholar EM. Role of tyrosine kinase inhibitors in cancer therapy. J Pharmacol Exp Ther. 2005;315(3):971–9. PubMed PMID: 16002463. Epub 20050707. eng.

    Article  CAS  PubMed  Google Scholar 

  55. Yuan A, Kurtz SL, Barysauskas CM, Pilotte AP, Wagner AJ, Treister NS. Oral adverse events in cancer patients treated with VEGFR-directed multitargeted tyrosine kinase inhibitors. Oral Oncol. 2015;51(11):1026–33. PubMed PMID: 26403941. Epub 20151005. eng.

    Article  CAS  PubMed  Google Scholar 

  56. Boers-Doets CB, Epstein JB, Raber-Durlacher JE, Ouwerkerk J, Logan RM, Brakenhoff JA, et al. Oral adverse events associated with tyrosine kinase and mammalian target of rapamycin inhibitors in renal cell carcinoma: a structured literature review. Oncologist. 2012;17(1):135–44. PubMed PMID: 22207567. PMCID: PMC3267813. Epub 20111229. eng.

    Article  CAS  PubMed  Google Scholar 

  57. Khawaja SN, Bavia PF, Keith DA. Clinical characteristics, treatment effectiveness, and predictors of response to Pharmacotherapeutic interventions in burning mouth syndrome: a retrospective analysis. J Oral Facial Pain Headache. 2020;34(2):157–66. PubMed PMID: 32255581. eng, 157.

    Article  PubMed  Google Scholar 

  58. Johnson RWG. Sirolimus (Rapamune) in renal transplantation. Curr Opin Nephrol Hypertens. 2002;11(6):603–7. en, 603.

    Article  PubMed  Google Scholar 

  59. Trotter JF. Sirolimus in liver transplantation. Transplant Proc. 2003;35(3 Suppl):193S–200S. eng, S193.

    Article  CAS  PubMed  Google Scholar 

  60. de Oliveira MA, Martins E, Martins F, Wang Q, Sonis S, Demetri G, George S, et al. Clinical presentation and management of mTOR inhibitor-associated stomatitis. Oral Oncol. 2011;47(10):998–1003. eng, 998.

    Article  PubMed  Google Scholar 

  61. Martins F, de Oliveira MA, Wang Q, Sonis S, Gallottini M, George S, et al. A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients. Oral Oncol. 2013;49(4):293–8. eng, 293.

    Article  CAS  PubMed  Google Scholar 

  62. Lo Muzio L, Arena C, Troiano G, Villa A. Oral stomatitis and mTOR inhibitors: a review of current evidence in 20,915 patients. Oral Dis. 2018;24(1-2):144–71. eng, 144.

    Article  CAS  PubMed  Google Scholar 

  63. Al-Mohaya M, Treister N, Al-Khadra O, Lehmann L, Padwa B, Woo S-B. Calcineurin inhibitor-associated oral inflammatory polyps after transplantation. J Oral Pathol Med. 2007;36(9):570–4. eng.

    Article  PubMed  Google Scholar 

  64. Xu Y, Wen N, Sonis ST, Villa A. Oral side effects of immune checkpoint inhibitor therapy (ICIT): an analysis of 4683 patients receiving ICIT for malignancies at Massachusetts General Hospital, Brigham & Women’s Hospital, and the Dana-Farber Cancer Institute, 2011 to 2019. Cancer. 2021;127(11):1796–804. eng.

    Article  PubMed  Google Scholar 

  65. Li CC, Malik SM, Blaeser BF, Dehni WJ, Kabani SP, Boyle N, et al. Mucosal pigmentation caused by imatinib: report of three cases. Head Neck Pathol. 2012;6(2):290–5. PubMed PMID: 22209988. PMCID: PMC3370028. Epub 20111231. eng.

    Article  PubMed  Google Scholar 

  66. Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw—2014 update. J Oral Maxillofac Surg. 2014;72(10):1938–56. PubMed PMID: 25234529. Epub 20140505. eng.

    Article  PubMed  Google Scholar 

  67. Yarom N, Shapiro CL, Peterson DE, Van Poznak CH, Bohlke K, Ruggiero SL, et al. Medication-related osteonecrosis of the jaw: MASCC/ISOO/ASCO clinical practice guideline. J Clin Oncol. 2019;37(25):2270–90. PubMed PMID: 31329513. Epub 20190722. eng, 2270.

    Article  PubMed  Google Scholar 

  68. Khan AA, Morrison A, Kendler DL, Rizzoli R, Hanley DA, Felsenberg D, et al. Case-based review of osteonecrosis of the jaw (ONJ) and application of the international recommendations for management from the International Task Force on ONJ. J Clin Densitom. 2017;20(1):8–24. PubMed PMID: 27956123. Epub 20161209. eng.

    Article  PubMed  Google Scholar 

  69. Samim F, Epstein JB, Zumsteg ZS, Ho AS, Barasch A. Oral and dental health in head and neck cancer survivors. Cancers Head Neck. 2016;1(1):14. en.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Ruggiero S, Gralow J, Marx RE, Hoff AO, Schubert MM, Huryn JM, et al. Practical guidelines for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in patients with cancer. J Oncol Pract. 2006;2(1):7–14. eng, 7.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Caribé-Gomes F, Chimenos-Küstner E, López-López J, Finestres-Zubeldia F, Guix-Melcior B. Dental management of the complications of radio and chemotherapy in oral cancer. Med Oral. 2003;8(3):178–87. eng, spa.

    PubMed  Google Scholar 

  72. Japanese Study Group of Cooperative Dentistry with M, Hasegawa T, Kawakita A, Ueda N, Funahara R, Tachibana A, et al. A multicenter retrospective study of the risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in patients receiving oral bisphosphonate therapy: can primary wound closure and a drug holiday really prevent MRONJ? Osteoporos Int. 2017;28(8):2465–73. en, 2465.

    Article  Google Scholar 

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Authors and Affiliations

  1. Miami Cancer Institute, Miami, FL, USA

    Alessandro Villa

  2. Department of Translational Medicine, Herbert Wertheim College of Medicine, Miami, FL, USA

    Alessandro Villa

  3. Faculty, Department of Orofacial Sciences, University of California San Francisco, San Francisco, CA, USA

    Alessandro Villa

  4. Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospitals and Research Centres, Pakistan, Lahore, Pakistan

    Khawaja Shehryar Nasir

  5. Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MD, USA

    Ahmed S. Sultan

  6. University of Maryland Greenebaum Cancer Center, Baltimore, MD, USA

    Ahmed S. Sultan

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  1. Alessandro Villa
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  2. Khawaja Shehryar Nasir
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  3. Ahmed S. Sultan
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Correspondence to Alessandro Villa .

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Editors and Affiliations

  1. Quinnipiac University, Frank H Netter MD School of Medicine, North Haven, CT, USA

    Christine E. Niekrash

  2. Division of Oral and Maxillofacial Surgery, University of Connecticut, Farmington, CT, USA

    Elie M. Ferneini

  3. Surgery, Consultant in Oral and Maxillofacial, Carmel, IN, USA

    Michael T. Goupil

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Villa, A., Nasir, K.S., Sultan, A.S. (2023). Oral Management of the Chemotherapy Patient. In: Niekrash, C.E., Ferneini, E.M., Goupil, M.T. (eds) Dental Science for the Medical Professional. Springer, Cham. https://doi.org/10.1007/978-3-031-38567-4_31

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