Overview
- Provides state-of the art insight into current research on voltage-gared Ca2+ channels
- Broadens the understanding of how Ca2+ channelopathies can provide novel insight into therapies of rare diseases
- Discusses concepts of the regulation of Ca2+ channels by neurotransmitters, enzymes and drugs
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 279)
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About this book
The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
Keywords
Table of contents (12 chapters)
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Modulation
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Pharmacological Approaches
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Disease Insight from Channelopathies: Consequences for Pharmacology and Therapeutic Strategies
Editors and Affiliations
Bibliographic Information
Book Title: Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease
Editors: Jörg Striessnig
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/978-3-031-38437-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-38436-3Published: 01 August 2023
Softcover ISBN: 978-3-031-38439-4Due: 01 September 2023
eBook ISBN: 978-3-031-38437-0Published: 31 July 2023
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: XII, 316
Number of Illustrations: 70 b/w illustrations, 30 illustrations in colour
Topics: Pharmacology/Toxicology, Human Genetics, Human Physiology