Abstract
The corpus callosum (CC) is the main cerebral commissure connecting the two cerebral hemispheres. It consists of four parts: rostrum, genu, body, and splenium. CC abnormalities may be isolated or accompany other fetal intracranial pathologies. Ultrasonography (US) and magnetic resonance imaging (MRI) are very helpful in diagnosing developmental abnormalities of CC. In this illustrated article, information about the evaluation of fetal CC pathologies with US and MRI is explained.
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References
Malinger G, Paladini D, Haratz KK, Monteagudo A, Pilu GL, Timor-Tritsch IE. ISUOG Practice Guidelines (updated): sonographic examination of the fetal central nervous system. Part 1: performance of screening examination and indications for targeted neurosonography. Ultrasound Obstet Gynecol. 2020;56(3):476–84.
Rossi AC, Prefumo F. Additional value of fetal magnetic resonance imaging in the prenatal diagnosis of central nervous system anomalies: a systematic review of the literature. Ultrasound Obstet Gynecol. 2014;44(4):388–93.
Palmer EE, Mowat D. Agenesis of the corpus callosum: a clinical approach to diagnosis. Am J Med Genet C Semin Med Genet. 2014;166C:184.
Edwards TJ, Sherr EH, Barkovich AJ, Richards LJ. Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes. Brain. 2014;137(Pt 6):1579–613.
Lockwood CJ, Ghidini A, Aggarwal R, Hobbins JC. Antenatal diagnosis of partial agenesis of the corpus callosum: a benign cause of ventriculomegaly. Am J Obstet Gynecol. 1988;159:184.
Díaz-Guerrero L, Giugni-Chalbaud G, Sosa-Olavarría A. Assessment of pericallosal arteries by color Doppler ultrasonography at 11-14 weeks: an early marker of fetal corpus callosum development in normal fetuses and agenesis in cases with chromosomal anomalies. Fetal Diagn Ther. 2013;34(2):85–9.
Conturso R, Contro E, Bellussi F, Youssef A, Pacella G, Martelli F, Rizzo N, Pilu G, Ghi T. Demonstration of the pericallosal artery at 11-13 weeks of gestation using 3D ultrasound. Fetal Diagn Ther. 2015;37(4):305–9.
Li Y, Estroff JA, Khwaja O, Mehta TS, Poussaint TY, Robson CD, Feldman HA, Ware J, Levine D. Callosal dysgenesis in fetuses with ventriculomegaly: levels of agreement between imaging modalities and postnatal outcome. Ultrasound Obstet Gynecol. 2012;40(5):522–9.
Atlas SW, Shkolnik A, Naidich TP. Sonographic recognition of agenesis of the corpus callosum. AJR Am J Roentgenol. 1985;145(1):167–73.
Pilu G, Sandri F, Perolo A, Pittalis MC, Grisolia G, Cocchi G, Foschini MP, Salvioli GP, Bovicelli L. Sonography of fetal agenesis of the corpus callosum: a survey of 35 cases. Ultrasound Obstet Gynecol. 1993;3(5):318–29.
Malinger G, Lerman-Sagie T, Viñals F. Three-dimensional sagittal reconstruction of the corpus callosum: fact or artifact? Ultrasound Obstet Gynecol. 2006;28(5):742–3.
Merz E. Targeted depiction of the fetal corpus callosum with 3D-ultrasound. Ultraschall Med. 2010;31(5):441.
Bornstein E, Monteagudo A, Santos R, Keeler SM, Timor-Tritsch IE. A systematic technique using 3-dimensional ultrasound provides a simple and reproducible mode to evaluate the corpus callosum. Am J Obstet Gynecol. 2010;202(2):201.e1–5.
Prayer D, Malinger G, Brugger PC, Cassady C, De Catte L, De Keersmaecker B, et al. ISUOG Practice Guidelines: performance of fetal magnetic resonance imaging. Ultrasound Obstet Gynecol. 2017;49(5):671–80.
Tilea B, Alberti C, Adamsbaum C, Armoogum P, Oury JF, Cabrol D, Sebag G, Kalifa G, Garel C. Cerebral biometry in fetal magnetic resonance imaging: new reference data. Ultrasound Obstet Gynecol. 2009;33(2):173–81.
D’Antonio F, Pagani G, Familiari A, Khalil A, Sagies TL, Malinger G, Leibovitz Z, et al. Outcomes associated with isolated agenesis of the corpus callosum: a meta-analysis. Pediatrics. 2016;138(3):e20160445.
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Ercan, F., Turgut, A.Ç., Köylüoğlu, F. (2023). Prenatal Diagnosis of Anomalies of the Corpus Callosum with Three-Dimensional Ultrasound, Transvaginal Sonography, and Fetal MRI. In: Turgut, M., Tubbs, R.S., Turgut, A.T., Bui, C.C. (eds) The Corpus Callosum. Springer, Cham. https://doi.org/10.1007/978-3-031-38114-0_11
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DOI: https://doi.org/10.1007/978-3-031-38114-0_11
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