Skip to main content

Cardiac Channelopathies

  • Chapter
  • First Online:
Cardiovascular Manual for the Advanced Practice Provider
  • 179 Accesses

Abstract

Genetic testing is becoming increasingly important in many specialties, including cardiology. This allows for a provider to accurately diagnose a disease associated with a causative genetic mutation for the purpose of not only appropriate clinical management, but to screen family members who may be at risk, potentially decreasing morbidity and mortality. This chapter will provide a basic overview of genetic testing and discuss a few of the more common genetic inherited arrhythmia syndromes in cardiology.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Further Reading

  1. Moss AJ, Adams FH. Cardiac channelopathies, syncope and SCD (Chapter 20). In: Heart disease in infants, children and adolescents. Philadelphia: Wolters Kluwer; 2022. p. 534–50.

    Google Scholar 

  2. Wilde AAM, Ackerman MJ. Beta blockers in the treatment of congenital LQT syndrome: is one beta-blocker superior to another. JACC. 2014;64(13):1359–61.

    Article  PubMed  Google Scholar 

  3. Ackerman MJ. Genetic purgatory and the cardiac channelopathies: exposing the variants of uncertain/unknown significance issue. Heart Rhythm. 2015;12(11):2325–31.

    Article  PubMed  Google Scholar 

  4. Ackerman MJ, et al. HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies. Europace. 2011;13(8):1077–109.

    Article  PubMed  Google Scholar 

  5. HRS/EHRA/APHRS expect consensus statement on the diagnosis and management of patient with inherited primary arrhythmia syndromes. 2013.

    Google Scholar 

  6. Cho Y. Left cardiac sympathetic denervation: an important treatment option for patients with hereditary ventricular arrhythmias. J Arrhythm. 2016;32(5):340–3. Published online 2015 Oct. 29. https://doi.org/10.1016/j.joa.2015.08.002.

    Article  PubMed  Google Scholar 

  7. Schwartz PJ, Crotti L, Insolia R. Long-QT syndrome: from genetics to management. Circ Arrhythm Electrophysiol. 2012;5(4):868–77. https://doi.org/10.1161/CIRCEP.111.962019.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Krista Allshouse .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Allshouse, K. (2023). Cardiac Channelopathies. In: Musialowski, R., Allshouse, K. (eds) Cardiovascular Manual for the Advanced Practice Provider. Springer, Cham. https://doi.org/10.1007/978-3-031-35819-7_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-35819-7_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-35818-0

  • Online ISBN: 978-3-031-35819-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics