Abstract
The orbital cavity may harbor many types of mass lesions of different histological origin.
They may be classified into seven main groups: vascular, cystic, neurogenic, mesenchymal, lacrimal gland, lymphoproliferative and histiocytic, metastatic lesions. The clinical expression mainly depends on tumor location (anterior to posterior, superior-lateral to infero-medial) and growth rate. The diagnosis is obtained by orbital echography, computer tomography, and magnetic resonance. The management options include biopsy (fine needle, incisional or excisional), surgical excision of the lesion, radiotherapy, and chemotherapy. The surgical resection may be realized through mini-invasive orbital approaches, cranio-orbital or trans-orbital, or trans-sphenoidal endoscopic approaches. The orbital exenteration may be limited to selected cases of very invasive or recurrent tumors.
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References
Henderson JW. Orbital tumors. 3rd ed. New York, NY: Raven Press; 1994.
Bonavolontà G, Strianese D, Grassi P, et al. An analysis of 2,480 space-occupying lesions of the orbit from 1976 to 2011. Ophthalmic Plast Reconstr Surg. 2013;29(2):79–86. https://doi.org/10.1097/IOP.0B013E31827A7622.
Rootman J. Disease of the orbit. A multidisciplinary approach. 2nd ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2002.
Louis DN, Perry A, Wesseling P, et al. The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol. 2021;23(8):1231–51. https://doi.org/10.1093/NEUONC/NOAB106.
Nasr AMCG. Ultrasonography in orbital differential diagnosis. In: Karcioglu Z, editor. Orbital tumors. Cham: Springer; 2015.
Medel R, Balaguer Ó. Approach to diagnosis of orbital tumours, vol. 5. Basel: Karger; 2014. p. 46–72. https://doi.org/10.1159/000363716.
Lee WWEB. Imaging in orbital differential diagnosis. In: Karcioglu A, editor. Orbital tumors: diagnosis and management, vol. 10. Cham: Springer; 2015.
Bourne TDKZ. Orbital biopsy. In: Karcioglu A, editor. Orbital tumors: diagnosis and management, vol. 12. Cham: Springer; 2015.
Paluzzi A, Gardner PA, Fernandez-Miranda JC, et al. “Round-the-clock” surgical access to the orbit. J Neurol Surg B Skull Base. 2015;76(1):12–24. https://doi.org/10.1055/S-0033-1360580.
Abussuud Z, Ahmed S, Paluzzi A. Surgical approaches to the orbit: a neurosurgical perspective. J Neurol Surg B Skull Base. 2020;81(4):385–408. https://doi.org/10.1055/S-0040-1713941.
Abou-Al-Shaar H, Krisht KM, Cohen MA, et al. Cranio-orbital and Orbitocranial approaches to orbital and intracranial disease: eye-opening approaches for neurosurgeons. Front Surg. 2020;7:1. https://doi.org/10.3389/FSURG.2020.00001.
Mariniello G, Maiuri F, de Divitiis E, et al. Lateral orbitotomy for removal of sphenoid wing meningiomas invading the orbit. Neurosurgery. 2010;66(6 Suppl Operative):287. https://doi.org/10.1227/01.NEU.0000369924.87437.0B.
Andrade-Barazarte H, Jägersberg M, Belkhair S, et al. The extended lateral supraorbital approach and extradural anterior clinoidectomy through a frontopterio-orbital window: technical note and pilot surgical series. World Neurosurg. 2017;100:159–66. https://doi.org/10.1016/J.WNEU.2016.12.087.
Dallan I, Sellari-Franceschini S, Turri-Zanoni M, et al. Endoscopic transorbital superior eyelid approach for the management of selected spheno-orbital meningiomas: preliminary experience. Oper Neurosurg (Hagerstown). 2018;14(3):243–51. https://doi.org/10.1093/ONS/OPX100.
Zoia C, Bongetta D, Gaetani P. Endoscopic transorbital surgery for spheno-orbital lesions: how I do it. Acta Neurochir. 2018;160(6):1231–3. https://doi.org/10.1007/S00701-018-3529-5.
Vitulli F, D’Avella E, Solari D, et al. Primary ectopic orbital craniopharyngioma. Acta Neurochir. 2022;164(7):1979–84. https://doi.org/10.1007/S00701-021-04969-Y.
Bonavolontà P, Esmaeli B, Donna P, et al. Outcomes after eye-sparing surgery vs orbital exenteration in patients with lacrimal gland carcinoma. Head Neck. 2020;42(5):988–93. https://doi.org/10.1002/HED.26073.
Harris GJ, Jakobiec FA. Cavernous hemangioma of the orbit. J Neurosurg. 1979;51(2):219–28. https://doi.org/10.3171/JNS.1979.51.2.0219.
Bonavolontà P, Fossataro F, Attanasi F, Clemente L, Iuliano A, Bonavolontà G. Epidemiological analysis of venous malformation of the orbit. J Craniofac Surg. 2020;31(3):759–61. https://doi.org/10.1097/SCS.0000000000006095.
Strianese D, Bonavolontà G, Iuliano A, Mariniello G, Elefante A, Liuzzi R. Risks and benefits of surgical excision of orbital cavernous venous malformations (so-called cavernous hemangioma): factors influencing the outcome. Ophthalmic Plast Reconstr Surg. 2021;37(3):248–54. https://doi.org/10.1097/IOP.0000000000001767.
Shields JA, Kaden IH, Eagle RC, Shields CL. Orbital dermoid cysts: Clinicopathologic correlations, classification, and management the 1997 Josephine E Schueler Lecture. Ophthalmic Plast Reconstr Surg. 1997;13(4):265–76. https://doi.org/10.1097/00002341-199712000-00007.
Shields JA, Shields CL. Orbital cysts of childhood—classification, clinical features, and management. Surv Ophthalmol. 2004;49(3):281–99. https://doi.org/10.1016/j.survophthal.2004.02.001.
Roberts F, MacDuff EM. An update on mesenchymal tumours of the orbit with an emphasis on the value of molecular/cytogenetic testing. Saudi J Ophthalmol. 2018;32(1):3–12. https://doi.org/10.1016/J.SJOPT.2018.02.010.
Grover AK, Rastogi A, Chaturvedi KU, Gupta AK. Schwannoma of the orbit. Arch Craniofac Surg. 2015;16(2):128–9. https://doi.org/10.7181/ACFS.2015.16.2.67.
Mariniello G, de Divitiis O, Caranci F, Dones F, Maiuri F. Parasellar schwannomas: extradural vs extra-Intradural surgical approach. Oper Neurosurg (Hagerstown). 2018;14(6):627–38. https://doi.org/10.1093/ONS/OPX174.
National Cancer Institue. Childhood Rabdomyosarcoma Treatment- NCI, cancer.gov.
Jurdy L, Merks JHM, Pieters BR, et al. Orbital rhabdomyosarcomas: a review. Saudi J Ophthalmol. 2013;27(3):167–75. https://doi.org/10.1016/J.SJOPT.2013.06.004.
Goto H. Review of ocular tumor. In: Practical ophthalmology, vol. 24. Tokyo: Bunkodo; 2008.
Jenkins C, Rose GE, Bunce C, et al. Histological features of ocular adnexal lymphoma (REAL classification) and their association with patient morbidity and survival. Br J Ophthalmol. 2000;84(8):907–13. https://doi.org/10.1136/BJO.84.8.907.
Diagnosis and Management of Orbital Lymphoma—American Academy of Ophthalmology. Accessed 6 Dec 2022. https://www.aao.org/eyenet/article/diagnosis-management-of-orbital-lymphoma.
Espinoza GM. Orbital inflammatory pseudotumors: etiology, differential diagnosis, and management. Curr Rheumatol Rep. 2010;12(6):443–7. https://doi.org/10.1007/S11926-010-0128-8.
Takahira M, Ozawa Y, Kawano M, et al. Clinical aspects of IgG4-related orbital inflammation in a case series of ocular adnexal lymphoproliferative disorders. Int J Rheumatol. 2012;2012:635473. https://doi.org/10.1155/2012/635473.
Valvassori GE, Sabnis SS, Mafee RF, Brown MS, Putterman A. Imaging of orbital lymphoproliferative disorders. Radiol Clin N Am. 1999;37(1):135–50. https://doi.org/10.1016/S0033-8389(05)70083-X.
Magliozzi P, Strianese D, Bonavolontà P, et al. Orbital metastases in Italy. Int J Ophthalmol. 2015;8(5):1018. https://doi.org/10.3980/J.ISSN.2222-3959.2015.05.30.
Allen R. Orbital metastases: when to suspect? When to biopsy? Middle East Afr J Ophthalmol. 2018;25(2):60. https://doi.org/10.4103/MEAJO.MEAJO_93_18.
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Bonavolontà, G., Bonavolontà, P. (2023). Soft Tissue Orbital Tumors. In: Bonavolontà, G., Maiuri, F., Mariniello, G. (eds) Cranio-Orbital Mass Lesions. Springer, Cham. https://doi.org/10.1007/978-3-031-35771-8_16
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