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Diversities of Various Nanomaterials-Based Vaccines for Healthcare Applications

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Nanovaccinology

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Abstract

One of the most effective global public health initiatives is vaccination. But despite the abundance of extremely effective vaccines, there are still some infectious diseases for which there are no vaccines. To fully realize the potential of vaccine development for both newly emerging infectious diseases and illnesses for which there are currently no vaccines available, new technologies are required. The COVID-19 mRNA vaccines’ success demonstrates that nanoscale platforms are promising delivery vectors for efficient and secure vaccines. The development of drugs is significantly influenced by nanotechnology. Polymeric nanoparticles can transport drugs, proteins, and vaccine antigens to the desired site of action. Through mucosal administration, polymeric nanoparticles with lower cytotoxicity can shield drugs or antigens from degradation in unfavorable conditions. In addition, the uptake of nanoparticles by antigen-presenting cells can boost and trigger powerful immune responses. Nanomaterials are also frequently used in vaccine delivery systems because they can extend the half-life of the vaccine antigen. Inorganic nanoparticles, polymer-based nanoparticles, nanomaterial vaccines, the idea behind nanomaterial-based vaccines, and applications of nanomaterial-based vaccines in healthcare are the main topics of this review. In the context of drugs and vaccines, the use and potential of nano bases as delivery vehicles and adjuvants are discussed.

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Authors and Affiliations

  1. Department of Medicine Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Punjab, Pakistan

    Amjad Islam Aqib

  2. Faculty of Biosciences, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Punjab, Pakistan

    Mahreen Fatima

  3. University Centre for Research and Development (UCRD), Chandigarh University, Mohali, Punjab, India

    Kaushik Pal

  4. Department of Zoology, Govt Sadiq College Women University, Bahawalpur, Punjab, Pakistan

    Sana Zia & Tasleem Kausar

  5. Department of Poultry Science, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Punjab, Pakistan

    Muhammad Arslan

  6. Department of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Punjab, Pakistan

    Asyia Shafiq

  7. Faculty of Veterinary, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Punjab, Pakistan

    Junaid Sattar

  8. Department of Parasitology, University of Agriculture, Faisalabad, Punjab, Pakistan

    Tean Zaheer

Authors
  1. Amjad Islam Aqib
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  2. Mahreen Fatima
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  3. Kaushik Pal
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  4. Sana Zia
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  5. Muhammad Arslan
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  6. Asyia Shafiq
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  7. Junaid Sattar
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  8. Tean Zaheer
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  9. Tasleem Kausar
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Corresponding author

Correspondence to Amjad Islam Aqib .

Editor information

Editors and Affiliations

  1. University Centre for Research and Development (UCRD)Chandigarh University, Punjab, India

    Kaushik Pal

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Aqib, A.I. et al. (2023). Diversities of Various Nanomaterials-Based Vaccines for Healthcare Applications. In: Pal, K. (eds) Nanovaccinology. Springer, Cham. https://doi.org/10.1007/978-3-031-35395-6_1

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  • DOI: https://doi.org/10.1007/978-3-031-35395-6_1

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