Abstract
Sleep apnea syndrome (SAS) is a disease characterized by breathing pauses during sleep, causing intermittent phenomena of hypoxia, which are repeated over time [1]. As resumed in previous chapters, OSA could be due to recurrent/partial or complete obstructions (hypopnea/apnea) of the upper airway during sleep [2], which takes the name of obstructive sleep apnea (OSA) and/or due to recurrent abnormal breathing pauses of central origin, without the evidence of upper respiratory obstruction, defined “Central Sleep Apnea” (CSA) [3]. Understanding the genesis of these disorders is essential to make up a complete overview, at least for what concerns fragile subjects, such as elderly patients.
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References
Young T, Palta M, Dempsey J, et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328(17):1230–5.
Berg S. Obstructive sleep apnoea syndrome: current status. Clin Respir J. 2008;2(4):197–201.
Bonsignore MR, Randerath W, Schiza S, et al. European Respiratory Society statement on sleep apnoea, sleepiness and driving risk. Eur Respir J. 2021;57(2):2001272.
The report of an American Academy of Sleep Medicine Task force. Sleep. 1999;22:667–89.
North BJ, Sinclair DA. The intersection between aging and cardiovascular disease. Circ Res. 2012;110(8):1097–108.
Schubert CR, Cruickshanks KJ, Dalton DS, et al. Prevalence of sleep problems and quality of life in an older population. Sleep. 2002;25:48–52.
Hass D, Foster G, Nieto J, et al. Age-dependent associations between sleep disordered breathing and hypertension. Circulation. 2005;111:614–21.
Hader C, Schroeder A, Hinz M, et al. Sleep disordered breathing in the elderly: comparison of women and men. J Physiol Pharmacol. 2005;56:85–91.
Gabbay IE, Lavie P. Age- and gender-related characteristics of obstructive sleep apnea. Sleep Breath. 2012;16(2):453–60.
Kollias I, Krogstad O. Adult craniocervical and pharyngeal changes—a longitudinal cephalometric study between 22 and 42 years of age. Part I: morphological craniocervical and hyoid bone changes. Eur J Orthod. 1999;21(4):333–44.
Lévy P, Kohler M, McNicholas WT, et al. Obstructive sleep apnoea syndrome. Nat Rev Dis Primers. 2015;1:15,015.
Panaszek B, Machaj Z, Bogacka E, Lindner K. Chronic disease in the elderly: a vital rationale for the revival of internal medicine. Pol Arch Med Wewn. 2009;119(4):248–54.
Wang S, Niu X, Zhang P, et al. Analysis of OSAS incidence and influential factors in middle-aged and elderly patients with hypertension. Minerva Med. 2019;110(2):115–20.
Unal Y, Ozturk DA, Tosun K, et al. Association between obstructive sleep apnea syndrome and waist-to-height ratio. Sleep Breath. 2019;23(2):523–9.
Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013;309(1):71–82.
Marin M, Gascon JM, Carrizo S, GispertInt J. Prevalence of sleep apnoea syndrome in the Spanish adult population. Epidemiology. 1997;26(2):381–6.
Dewan NA, Nieto FJ, Somers VK. Intermittent hypoxemia and OSA: implications for comorbidities. Chest. 2015;147(1):266–74.
Ge X, Han F, Huang Y, et al. Is obstructive sleep apnea associated with cardiovascular and all-cause mortality? PLoS One. 2013;8:e69432.
Marrone O, Lo Bue A, Salvaggio A, et al. Comorbidities and survival in obstructive sleep apnoea beyond the age of 50. Eur J Clin Investig. 2013;43:27–33.
Dodds S, Williams LJ, Roguski A, et al. Mortality and morbidity in obstructive sleep apnoea–hypopnoea syndrome: results from a 30-year prospective cohort study. ERJ Open Res. 2020;6(3):00057-202.
Emamian F, Khazaie H, Tahmasian M, et al. The association between obstructive sleep apnea and Alzheimer's disease: a meta-analysis perspective. Front Aging Neurosci. 2016;8:78.
Cohen-Zion M, Stepnowsky C, Marler T, et al. Changes in cognitive function associated with sleep disordered breathing in older people. J Am Geriatr Soc. 2001;49(12):1622–7.
Andrade AG, Bubu OM, Varga AW, Osorio RS. The relationship between obstructive sleep apnea and Alzheimer's disease. 2018;64(s1):S255-S270. J Alzheimers Dis.
Wahner-Roedler DL, Olson EJ, Narayanan S, et al. Gender-specific differences in a patient population with obstructive sleep apnea–hypopnea syndrome. Gend Med. 2007;4(4):329–38.
Chung S. Effects of age on the clinical features of men with obstructive sleep apnea syndrome. Respiration. 2009;78:23.
Iannella G, Magliulo G, Lo Iacono CAM. Positional obstructive sleep apnea syndrome in elderly patients. Int J Environ Res Public Health. 2020;17(3):1120.
Labarca G, Saavedra D, Dreyse J, Jorquera J, Barbe F. Efficacy of CPAP for improvements in sleepiness, cognition, mood, and quality of life in elderly patients with OSA: systematic review and meta-analysis of randomized controlled trials. Chest. 2020;158(2):751–64. Epub 2020 Apr 11.
Wang G, Goebel JR, Li C, et al. Therapeutic effects of CPAP on cognitive impairments associated with OSA. J Neurol. 2020;267(10):2823–8.
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Emanuela, F., Maria, P.F., Stefano, D.G. (2023). Sleep Apnea Syndrome in Elderly. In: Baptista, P.M., Lugo Saldaña, R., Amado, S. (eds) Obstructive Sleep Apnea. Springer, Cham. https://doi.org/10.1007/978-3-031-35225-6_33
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