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The Relationship Between Folic Acid and Healthy Reproduction

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New Technologies, Development and Application VI (NT 2023)

Part of the book series: Lecture Notes in Networks and Systems ((LNNS,volume 707))

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Abstract

Since 1991, when the UK Medical Research Council first confirmed that folic acid supplementation before and after pregnancy can prevent the occurrence of NTDs (neural tube malformations) and reduce the incidence by 50–70%, the preventive effect of folic acid on NTDs has been recognized as one of the most exciting medical discoveries of the late 20th century. Since then, the effects of folic acid on fetal growth and development have been the focus of scholars’ research. More and more studies have shown that folic acid is associated with other fertility problems as well as fetal birth defects. In particular, many studies in recent years have explained the relationship between folic acid and healthy fertility from the epigenetic aspects such as genetic and histone modification. Therefore, combined with relevant literature, the author reviews some current research results, in order to clarify the specific pathogenesis and other unsolved problems through further research.

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Author information

Authors and Affiliations

  1. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China

    Jia Lijun

  2. Department of Agricultural Science, University of Naples “Federico II”, Via Università 100, 80055, Portici, Naples, Italy

    Andrea Formato & Raffaele Romano

  3. University of Salerno, MEID4 srl, Academic Spin-Off, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy

    Giampiero Celenta

Authors
  1. Jia Lijun
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  2. Andrea Formato
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  3. Giampiero Celenta
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  4. Raffaele Romano
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Corresponding author

Correspondence to Andrea Formato .

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Editors and Affiliations

  1. Academy of Sciences and Arts of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina

    Isak Karabegovic

  2. City University of London, London, UK

    Ahmed Kovačević

  3. Faculty of Traffic and Transport Sciences, University of Zagreb, Zagreb, Croatia

    Sadko Mandzuka

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Lijun, J., Formato, A., Celenta, G., Romano, R. (2023). The Relationship Between Folic Acid and Healthy Reproduction. In: Karabegovic, I., Kovačević, A., Mandzuka, S. (eds) New Technologies, Development and Application VI. NT 2023. Lecture Notes in Networks and Systems, vol 707. Springer, Cham. https://doi.org/10.1007/978-3-031-34721-4_14

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