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Sleep and Epilepsy

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Abstract

Sleep and epilepsy have a mutual connection. Sleep may activate interictal epileptiform discharges (IEDs) and/or trigger seizures. Comorbid sleep-related disorders which chronically induce sleep fragmentation may worsen seizures frequency. At the same time, IEDs and seizures result in a long-term quali-quantitative disruption of sleep architecture, increasing arousals and infra-hypnic awakenings, and decreasing sleep efficiency, which in turn could facilitate seizures. In addition, many anticonvulsant drugs may affect sleep macrostructure and sleep disorders.

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Authors and Affiliations

  1. IRCCS Istituto delle Scienze neurologiche di Genova, Istituto Giannina Gaslini, Genova, Italy

    Lino Nobili

  2. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

    Angelica Montini & Federica Provini

  3. Department of Clinical Neurosciences, Neurology, Sleep Disorders Center, IRCCS San Raffaele Scientific Institute, Milan, Italy

    Marco Zucconi

  4. Hmh Jfk University Medical Center and Neuroscience Institute, Hackensack Meridian School of Medicine at Seton Hall University, South Orange and Nutley, NJ, USA

    Sudhansu Chokroverty

  5. Rutgers Robert Wood Johnson University Medical Center, New Brunswick, NJ, USA

    Sudhansu Chokroverty

  6. IRCCS Institute of Neurological Sciences, UOC NeuroMet, Bellaria Hospital, Bologna, Italy

    Federica Provini

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  1. Lino Nobili
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  2. Angelica Montini
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  4. Sudhansu Chokroverty
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  5. Federica Provini
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Correspondence to Lino Nobili .

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  1. Beth Israel Deaconess Medical Center, Boston, MA, USA

    Robert J. Thomas

  2. JFK Neuroscience Institute, Hackensack Meridian Health-JFK University Medical Center, Edison, NJ, USA

    Sushanth Bhat

  3. HMH JFK University Medical Center and Neuroscience Institute, Hackensack Meridian School of Medicine at Seton Hall University, South Orange and Nutley, NJ, USA

    Sudhansu Chokroverty

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Nobili, L., Montini, A., Zucconi, M., Chokroverty, S., Provini, F. (2023). Sleep and Epilepsy. In: Thomas, R.J., Bhat, S., Chokroverty, S. (eds) Atlas of Sleep Medicine. Springer, Cham. https://doi.org/10.1007/978-3-031-34625-5_29

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