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Upper Airway Humidification: Physiology and Clinical Implications

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Upper Airway Disorders and Noninvasive Mechanical Ventilation

Abstract

The humidification of the inspired air is one of the major functions of the upper airway. Although its physiology is already recognized, the clinical consequences of its disturbances are less established. In this chapter, we will review the concept of humidity, the process of the upper airway humidification, and the implications of insufficient and excessive humidification, with biological and artificial ventilation. Using these concepts, we will assess its significance in upper airway symptoms and how it correlates to the ventilation adherence.

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References

  1. Jackson C. Humidification in the upper respiratory tract: a physiological overview. Intensive Crit Care Nurs. 1996;12:27–32.

    Article  CAS  PubMed  Google Scholar 

  2. Plotnikow GA, Accoce M, Navarro E, Tiribelli N. Humidification and heating of inhaled gas in patients with artificial airway. A narrative review. Rev Bras Ter Intensiva. 2018;30:86. https://doi.org/10.5935/0103-507x.20180015.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Reinikainen LM, Jaakkola JJ. Significance of humidity and temperature on skin and upper airway symptoms. Indoor Air. 2003;13:344–52.

    Article  CAS  PubMed  Google Scholar 

  4. Andersen IB, Lundqvist GR, Proctor DF, Jensen PL. Human nasal mucosal function under four controlled humidities 1–3. Am Rev Respir Dis. 1972;106:438–49.

    Article  CAS  PubMed  Google Scholar 

  5. Zhu D, Wu M, Cao Y, Lin S, Xuan N, Zhu C, Li W, Shen H. Heated humidification did not improve compliance of positive airway pressure and subjective daytime sleepiness in obstructive sleep apnea syndrome: a meta-analysis. PLoS One. 2018;13:e0207994. https://doi.org/10.1371/journal.pone.0207994.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Grau-Bartual S, Al-Jumaily AM. Prediction of upper airway dryness and optimal continuous positive airway pressure conditions. J Biomech. 2020;112:110037.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Soudorn C, Muntham D, Reutrakul S, Chirakalwasan N. Effect of heated humidification on CPAP therapy adherence in subjects with obstructive sleep apnea with nasopharyngeal symptoms. Respir Care. 2016;61:1151–9.

    Article  PubMed  Google Scholar 

  8. Nilius G, Franke KJ, Domanski U, Schroeder M, Ruhle KH. Effect of APAP and heated humidification with a heated breathing tube on adherence, quality of life, and nasopharyngeal complaints. Sleep Breath. 2015;20:43–9.

    Article  PubMed  Google Scholar 

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Correspondence to Filipa Torres Silva .

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Silva, F.T., Conde, B. (2023). Upper Airway Humidification: Physiology and Clinical Implications. In: Esquinas, A.M., De Vito, A., Barbetakis, N. (eds) Upper Airway Disorders and Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-031-32487-1_4

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  • DOI: https://doi.org/10.1007/978-3-031-32487-1_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-32486-4

  • Online ISBN: 978-3-031-32487-1

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