Abstract
Gynecomastia is a benign enlargement of mammary gland tissue in males and must be distinguished from pure lipomastia and carcinoma. By itself, gynecomastia is not a disease entity, but a symptom of a variety of causes leading to a dysbalance between androgens and estrogens. Gynecomastia can cause considerable psychological and psychosocial problems (body dysphoria, reduced self-esteem, etc.). Gynecomastia of the newborn, at puberty and in old age, are considered almost “physiological.” It is important to recognize whether gynecomastia is caused by an estrogen or hCG-producing testicular tumor requiring prompt treatment. Common causes of gynecomastia are primary (e.g., Klinefelter syndrome) and secondary hypogonadism. Numerous medications, drugs, and products of daily use (cosmetics and food) as well as occupational exposure can cause gynecomastia. Treatment consists first of all in the removal of causative agents. In addition, there is no evidence-based pharmacological therapy, only treatment trials with drugs not approved for this indication. Empathic guidance of the patient is the task of the treating physician. Ultimately, only gynecomastectomy remains, which should be performed by a plastic surgeon experienced in senology.
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Nieschlag, E. (2023). Gynecomastia. In: Nieschlag, E., Behre, H.M., Kliesch, S., Nieschlag, S. (eds) Andrology. Springer, Cham. https://doi.org/10.1007/978-3-031-31574-9_32
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