Skip to main content
SpringerLink
Log in

Bioactive Compounds and Biological Activities of Hedychium Species

  • Living reference work entry
  • First Online:
Bioactive Compounds in the Storage Organs of Plants

Part of the book series: Reference Series in Phytochemistry ((RSP))

  • 37 Accesses

Abstract

The genus Hedychium J. Koenig (Family: Zingiberaceae) is an important source of traditional folk medicine in India, helpful considering traditional and modern medical practices. The herbs of this genus also have potent antiepileptic, anticonvulsant, and aphrodisiac effects, and are useful in intermittent claudication, atherosclerosis, and chronic active hepatitis. This chapter aims to provide a comprehensive overview of the medicinal and traditional uses of numerous Hedychium species, their endemicity, isolated bioactive constituents, essential oils, and biological activities. Several labdane diterpenes isolated from the genus are highlighted for their potentially extensive bioactivity. The genuine discussion of this detailed and comprehensive comparative analysis presented here provides valuable information on the currently used Hedychium species and paves the way for the study of other useful Hedychium species in terms of ethnobotany, phytochemistry, and the mechanistic approach for new drug discovery and their therapeutic potential.

Credit authorship contribution statement

Avneesh Rawat: Planning original draft, collecting the literature, and writing manuscripts. Om Prakash: Writing the literature, providing some professional guidance and valuable advice during the writing process of this paper, and Formal analysis. Ravendra Kumar: Writing original draft. Sushila Arya: Collected and sorted out the relevant literature and other information. D.S. Rawat: Analyzed, reviewed, and edited the manuscript. Satya Kumar: Formal analysis, provide valuable advice during the writing process of this paper.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References

  1. The Plant List (2013) Version 1.1. http://www.theplantlist.org/

  2. WFO (2021) World Flora Online. Facilitated by the Royal Botanic Gardens, Kew. http://www.worldfloraonline.org

  3. POWO (2019) Plants of the World Online. Facilitated by the Royal Botanic Gardens, Kew. http://www.plantsoftheworldonline.org/

  4. Catalogue of Life (2021) Species 2000 & ITIS catalogue of life, 2021-06-10. Digital resource at www.catalogueoflife.org. Species 2000: Naturalis, Leiden. ISSN 2405-8858

  5. Sanoj E (2011) Taxonomic revision of the genus Hedychium J Koenig Zingiberaceae in India. PhD. Thesis. University of Calicut, Kerala. http://hdl.handle.net/10603/80898.

  6. Ashokan A, Gowda V (2019) Hedychium ziroense (Zingiberaceae), a new species of ginger lily from Northeast India. PhytoKeys 117:73

    Article  Google Scholar 

  7. Wu TL, Larsen K (2000) Zingiberaceae. Flora of China 24: 322–377

    Google Scholar 

  8. Fiqa AP, Fauziah F, Lestari DA, Budiharta S (2019) The importance of in-situ conservation area in mining concession in preserving diversity, threatened and potential floras in East Kalimantan, Indonesia. Biodivers J Biol Divers 20:198–210

    Article  Google Scholar 

  9. Wongsuwan P, Picheansoonthon C (2011) Taxonomic Revision of the Genus Hedychium J. König (Zingiberaceae) in Thailand (Part I). J R Inst Thail 3:126–149

    Google Scholar 

  10. Holttum RE (1950) The Zingiberaceae of the Malay Peninsula. Gard Bull Singapore 13:48–65

    Google Scholar 

  11. Mabberley DJ (2017) Mabberley’s Plant-Book A portable dictionary of plants, their classification and uses. Cambridge University Press, Cambridge UK, p 1102

    Book  Google Scholar 

  12. Smith RM (1991) Notes relating to the Flora of Bhutan: XVII. Zingiberaceae: Zingiberaceae. Edinb J Bot 48:23–25

    Article  Google Scholar 

  13. Jain SK, Prakash V (1995) Zingiberaceae in India – phytogeography and endemism. Rheedea 5:154–159

    Google Scholar 

  14. Sarangthem N, Talukdar NC, Thongam B (2013) Collection and evaluation of Hedychium species of Manipur, Northeast India. Genet Resour Crop Evol 60:13–21

    Article  Google Scholar 

  15. Thomas S, Mani B, Britto SJ (2015) A new species of Hedychium (Zingiberaceae) from the southern Western Ghats, India. Webbia 70:221–225

    Article  Google Scholar 

  16. Picheansoonthon C, Wongsuwan P (2009) Hedychium champasakense (Zingiberaceae), a new species from Southern Laos. Taiwania 54:145–148

    Google Scholar 

  17. Hung DV, Potokin AF (2019) Diversity of plant species composition and forest vegetation cover of Dong Nai culture and nature reserve, Vietnam. In: IOP conference series: earth and environmental science, vol 316. IOP Publishing, pp 012009

    Google Scholar 

  18. Branney TME (2005) Hardy Gingers: including Hedychium, Roscocea, and Zingiber, Royal Horticultural Society plant collector guide. Timber Press, Portland, p 267

    Google Scholar 

  19. Tobias AB, Malabrigo PL, Umali AGA, Eduarte GT, Mohagan AB, Mendez NP (2019) Taxonomy, recollection and conservation of newly discovered populations of Hedychium philippinense (Zingiberaceae): an endemic and threatened species in The Philippines. Asian J Conserv Biol 8:88–92

    Google Scholar 

  20. Thapa P, Prakash O, Rawat A, Kumar R, Srivastava RM, Rawat DS, Pant AK (2020) Essential oil composition, antioxidant, anti-inflammatory, insect antifeedant and sprout suppressant activity in essential oil from aerial parts of Cotinus coggygria Scop. J Essent Oil Bear Pl 23:65–76

    Article  CAS  Google Scholar 

  21. Srimal RC, Sharma SC, Tandon JS (1984) Anti-inflammatory and other pharmacological effects of Hedychium spicatum (Buch-Hem). Indian J Pharm 16:143

    CAS  Google Scholar 

  22. Sharma SC, Tandon JS, Dhar MM (1976) 7-Hydroxyhedychenone, a furanoditerpene from Hedychium spicatum. Phytochemistry 15:827–828

    Article  CAS  Google Scholar 

  23. Rawat A, Prakash O, Kumar R, Arya S, Srivastava RM (2021) Hedychium spicatum Sm.: Chemical composition with biological activities of methanolic and ethylacetate oleoresins from rhizomes. J Biol Act Prod Nat 11:269–288

    CAS  Google Scholar 

  24. Shrotriya S, Ali MS, Saha A, Bachar SC, Islam MS (2007) Anti-inflammatory and analgesic effects of Hedychium coronarium Koen. Pak J Pharm Sci 20:47–51

    CAS  PubMed  Google Scholar 

  25. Van Kiem P, Thuy NTK, Anh HLT, Nhiem NX, Van Minh C, Yen PH, Ban NK, Hang DT, Tai BH, Van Tuyen N, Mathema VB (2011) Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells. Bioorg Med Chem Lett 21:7460–7465

    Article  CAS  PubMed  Google Scholar 

  26. Chaturvedi GN, Sharma BD (1975) Clinical studies on Hedychium spicatum (Shati): An antiasthmatic drug. Indian J Med Res 10:941

    Google Scholar 

  27. Prasanna H, Hukkeri VI, Hunasagi BS, Marihal SC, Kulkarni RV, Patil CC, Kotnal RB, Kulkarni RG (2002) Screening of Hedychium spicatum for hepatoprotective activity in albino rats. Indian Drugs 39:117–119

    Google Scholar 

  28. Tandan SK, Gupta S, Lal J (1997) Analgesic and anti-inflammatory effects of Hedychium spicatum. Indian J Pharm Sci 59:148–150

    Google Scholar 

  29. Dash PR, Nasrin M, Saha MR (2011) Evaluation of analgesic and neuropharmacological activities of methanolic rhizome extract of Hedychium coronarium. Int J Pharm Sci Res 2:979

    Google Scholar 

  30. Ghildiyal S, Gautam MK, Joshi VK, Goel RK (2012) Pharmacological evaluation of extracts of Hedychium spicatum (Ham-ex-Smith) rhizome. Anc Sci Life 31:117

    Article  PubMed  PubMed Central  Google Scholar 

  31. Tian M, Wu X, Lu T, Zhao X, Wei F, Deng G, Zhou Y (2020) Phytochemical analysis, antioxidant, antibacterial, cytotoxic, and enzyme inhibitory activities of Hedychium flavum rhizome. Front Pharmacol 1493, p.572659.

    Google Scholar 

  32. Guzman L, Nerio LS, Venturini W, Macias JP, Donoso W, Forero-Doria O (2020) Antiplatelet and antibacterial activities of essential oils obtained from rhizomes and leaves of Hedychium coronarium J. Koenig. An Acad Bras Ciênc 92:e20190615

    Article  CAS  PubMed  Google Scholar 

  33. Reddy PP, Tiwari AK, Rao RR, Madhusudhana K, Rao VRS, Ali AZ, Babu KS, Rao JM (2009) New Labdane diterpenes as intestinal α-glucosidase inhibitor from antihyperglycemic extract of Hedychium spicatum (Ham. Ex Smith) rhizomes. Bioorg Med Chem Lett 19:2562–2565

    Article  Google Scholar 

  34. Reddy PP, Rao RR, Shashidhar J, Sastry BS, Rao JM, Babu KS (2009) Phytochemical investigation of labdane diterpenes from the rhizomes of Hedychium spicatum and their cytotoxic activity. Bioorg Med Chem Lett 19:6078–6081

    Article  CAS  PubMed  Google Scholar 

  35. Reddy PP, Rao RR, Rekha K, Babu KS, Shashidhar J, Shashikiran G, Lakshmi VV, Rao JM (2009) Two new cytotoxic diterpenes from the rhizomes of Hedychium spicatum. Bioorg Med Chem Lett 19:192–195

    Article  CAS  PubMed  Google Scholar 

  36. Rawat A, Thapa P, Prakash O, Kumar R, Pant AK, Srivastava RM, Rawat DS (2019) Chemical composition, herbicidal, antifeedant and cytotoxic activity of Hedychium spicatum Sm.: A Zingiberaceae herb. Trends Phytochem Res 3:123–136

    CAS  Google Scholar 

  37. Ray A, Jena S, Dash B, Sahoo A, Kar B, Patnaik J, Panda PC, Nayak S, Mahapatra N (2019b) Hedychium coronarium extract arrests cell cycle progression, induces apoptosis, and impairs migration and invasion in HeLa cervical cancer cells. Cancer Manag Res 11:483

    Article  PubMed  PubMed Central  Google Scholar 

  38. Shifah F, Tareq AM, Sayeed MA, Islam MN, Emran TB, Ullah MA, Mukit MA, Ullah A (2020) Antidiarrheal, cytotoxic and thrombolytic activities of methanolic extract of Hedychium coccineum leaves. J Adv Biotechnol Exp Ther 11:12

    Google Scholar 

  39. Li YP, Zhao SM, Xu JJ, Zeng GZ, Li Y, Tan NH, Yang Y (2016) New Labdane diterpenes from Hedychium yunnanense with cytotoxicity and inhibitory effects on nitric oxide production. Nat Prod Res 30:2669–2674

    Article  CAS  PubMed  Google Scholar 

  40. Songsri S, Nuntawong N (2016) Cytotoxic Labdane Diterpenes from Hedychium ellipticum Buch.-Ham. ex Sm. Molecules 21:749

    Article  PubMed  PubMed Central  Google Scholar 

  41. Rao GV, Mukhopadhyay T, Madhavi MSL, Lavakumar S (2011) Chemical examination and hair growth studies on the rhizomes of Hedychium spicatum Buch.-Ham. Phcog Commn 1:90–93

    Article  CAS  Google Scholar 

  42. Dixit VK, Varma KC (1976) Anthelmintic properties of essential oils from rhizomes of Hedychium coronarium Koeing and Hedychium spicatum Koeing. Indian J Pharm 37:143–144

    Google Scholar 

  43. Joshi S, Chanotiya CS, Agarwal G, Prakash O, Pant AK, Mathela CS (2008) Terpenoid compositions, and antioxidant and antimicrobial properties of the rhizome essential oils of different Hedychium species. Chem Biodivers 5:299–309

    Article  CAS  PubMed  Google Scholar 

  44. Ho JC (2011) Antimicrobial, mosquito larvicidal and antioxidant properties of the leaf and rhizome of Hedychium coronarium. J Chin Chem Soc 58:563–567

    Article  CAS  Google Scholar 

  45. Bisht GS, Awasthi AK, Dhole TN (2006) Anti-microbial activity of Hedychium spicatum. Fitoterapia 77:240–242

    Article  CAS  PubMed  Google Scholar 

  46. Dan G, Shiburaj S, Sethuraman MG, George V (2005) Chemical composition and antibacterial activity of the rhizome oil of Hedychium larsenii. Acta Pharma 55:315–320

    Google Scholar 

  47. Prakash O, Rajput M, Kumar M, Pant AK (2010) Chemical composition and antibacterial activity of rhizome oils from Hedychium coronarium Koenig and Hedychium spicatum Buch-Ham. J Essent Oil Bear Pl 13:250–259

    Article  CAS  Google Scholar 

  48. dos Santos MRA, Lima RA, de Freitas Fernandes C, Braga AGS, Facundo VA (2014) Antifungal activity of Hedychium coronarium J. König essential oil against Fusarium oxysporum Schlecht and Thanatephorus cucumeris (AB Frank) Donk in-vitro. Ciênc Nat 36:683–687

    Google Scholar 

  49. Goswami S, Pandey A, Tripathi P, Singh A, Rai A (2011) An in-vitro evaluation of the anthelmintic activity of Hedychium spicatum rhizomes and Zingiber zerumbet rhizomes on the Pheritima Posthuma model: A comparative study. Pharm Res 3:140

    Google Scholar 

  50. Sravani T, Paarakh PM (2011) Hedychium spicatum Buch. Ham.- an overview. Pharmacol Online 2:633–642

    Google Scholar 

  51. Jadhav V, Kore A, Kadam VJ (2007) In-vitro pediculicidal activity of Hedychium spicatum essential oil. Fitoterapia 78:470–473

    Article  CAS  PubMed  Google Scholar 

  52. Sakhanokho HF, Sampson BJ, Tabanca N, Wedge DE, Demirci B, Baser KHC, Bernier UR, Tsikolia M, Agramonte NM, Becnel JJ, Chen J (2013) Chemical composition, antifungal and insecticidal activities of Hedychium essential oils. Molecules 18:4308–4327

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  53. Prakash O, Chandra M, Punetha H, Pant AK, Rawat DS (2016) Spiked Ginger Lily (Hedychium spp.) oils. In: Essential oils in food preservation, flavor and safety. Academic Press, pp 737–750. https://doi.org/10.1016/B978-0-12-416641-7.00084-5.

  54. Chetry LB, Basar K, Taye K, Taka T, Tsering J, Wangpan T, Bharali MK (2018) Medicinal plants used against gastrointestinal disorders among the Adi Tribe of Eastern Himalaya. NeBIO 9:93–101

    Google Scholar 

  55. Sravani T, Paarakh PM, Vedamurthy AB (2012) Isolation of phytoconstituents from the rhizomes of Hedychium spicatum Buch. Ham. J Pharm Res 5:526–527

    Google Scholar 

  56. Quattrocchi U (2012) CRC world dictionary of medicinal and poisonous plants: common names, scientific names, eponyms, synonyms, and etymology (5 Volume Set) CRC press, Boca Raton. https://doi.org/10.1016/B978-0-12-416641-7.00084-5

  57. Suksri S, Premcharoen S, Thawatphan C, Sangthongprow S (2005) Ethnobotany in Bung Khong Long non-hunting area, northeast Thailand. Agric Nat Resour 39:519–533

    Google Scholar 

  58. Devi NB, Singh PK, Das AK (2014) Ethnomedicinal utilization of Zingiberaceae in the valley districts of Manipur. J Environ Sci Toxicol Food Technol 8:21–23

    Google Scholar 

  59. Itokawa H, Morita H, Katou I, Takeya K, Cavalheiro AJ, de Oliveira RC, Ishige M, Motidome M (1988) Cytotoxic diterpenes from the rhizomes of Hedychium coronarium. Planta Med 54:311–315

    Article  CAS  PubMed  Google Scholar 

  60. Matsuda H, Morikawa T, Sakamoto Y, Toguchida I, Yoshikawa M (2002) Labdane-type diterpenes with inhibitory effects on increase in vascular permeability and nitric oxide production from Hedychium coronarium. Bioorg Med Chem 10:2527–2534

    Article  CAS  PubMed  Google Scholar 

  61. Morikawa T, Matsuda H, Sakamoto Y, Ueda K, Yoshikawa M (2002) New farnesane-type sesquiterpenes, hedychiols A and B 8, 9- diacetate, and inhibitors of degranulation in RBL-2H3 cells from the rhizome of Hedychium coronarium. Chem Pharm Bull 50:1045–1049

    Article  CAS  Google Scholar 

  62. Kapale R (2012) Ethnobotany of Baiga tribals with references to utilization of forest resources in Amarkantak Biosphere Reserve (India). Bull Environ Pharmacol Life Sci 1:73–76

    Google Scholar 

  63. Kasarkar AR, Kulkarni DK (2016) Traditional knowledge of medicines belonging to Family Zingiberaceae from South Western Maharashtra. Int J Bot Stud, India, p 1

    Google Scholar 

  64. Aziz MA, Habib MR, Karim MR (2009) Antibacterial and cytotoxic activities of Hedychium coronarium J. Koenig. Res J Agric Biol Sci 5:969–972

    Google Scholar 

  65. Prakash O, Anjum Z, Pant AK, Hore SK, Mathela CS (2005) Effect of aqueous extracts of Hedychium coronarium Koen. rhizome and Zingiber roseum Rosc. seed and rhizome on rat duodenal smooth muscle. J Vet Pharmcol Toxicol 4:50–51

    Google Scholar 

  66. Thomas VP, Jose J, Saranya Mol ST, Thomas BT (2020) Ethnobotanical significance of Zingiberales: a case study in the Malaipandaram tribe of Southern Western Ghats of Kerala. Indian J Tradit Knowl 19:450–458

    Google Scholar 

  67. Leaman DJ, Arnason JT, Yusuf R, Sangat-Roemantyo H, Soedjito H, Angerhofer CK, Pezzuto JM (1995) Malaria remedies of the Kenyah of the Apo Kayan, East Kalimantan, Indonesian Borneo: a quantitative assessment of local consensus as an indicator of biological efficacy. J Ethnopharmacol 49:1–16

    Article  CAS  PubMed  Google Scholar 

  68. Lim MK (2011) Antimicrobial Activity of Essential Oils from Hedychium cylindricum (Zingiberaceae) in Kinabalu Park, Sabah. Doctoral dissertation, Universiti Malaysia Sabah

    Google Scholar 

  69. Kumar S, Ziereis K, Wiegrebe W, Müller K (2000) Medicinal plants from Nepal: evaluation as inhibitors of leukotriene biosynthesis. J Ethnopharmacol 70:191–195

    Article  CAS  PubMed  Google Scholar 

  70. Suksathan R, Sookkhee S, Anuntalabhochai S, Chansakaow S (2013) Chemical composition and antibacterial activity of rhizome oils from five Hedychium species. Nat Prod Commun 8:519–522

    CAS  PubMed  Google Scholar 

  71. Suksathan R, Anuntalabhochai S, Jampeetong A, Sookkhee S, Chansakaow S (2014) A phylogenetic analysis of Thai Hedychium (Zingiberaceae) and development of SCAR marker for Hedychium flavescens Carey ex Roscoe. Chiang Mai J Sci 41:286–297

    Google Scholar 

  72. Singh TT, Sharma HM (2018) An ethnobotanical study of monocotyledonous medicinal plants used by the scheduled caste community of Andro in Imphal East District, Manipur (India). Res J Life Sci Bioinform Pharm Chem Sci 4:55–72

    Google Scholar 

  73. Pan X, Zhang X (2014) Rapid Propagation of Hedychium flavum Roxb. J Trop Biol 4(2):189–193

    Google Scholar 

  74. Thomas S, Mani B (2016) Chemical composition, antibacterial and antioxidant properties of essential oil from the rhizomes of Hedychium forrestii var. palaniense Sanoj and M. Sabu. Indian J Pharm Sci 78:452–457

    Article  CAS  Google Scholar 

  75. Zhao Q, Qing C, Hao XJ, Han J, Zuo GY, Zou C, Xu GL (2008) Cytotoxicity of labdane-type diterpenoids from Hedychium forrestii. Chem Pharm Bull 56:210–212

    Article  CAS  Google Scholar 

  76. Zhao Q, Gao JJ, Qin XJ, Hao XJ, He HP, Liu HY (2018) Hedychins A and B, 6, 7-dinorlabdane diterpenoids with a peroxide bridge from Hedychium forrestii. Org Lett 20:704–707

    Article  CAS  PubMed  Google Scholar 

  77. Arruda M, Viana H, Rainha N, Neng NR, Rosa JS, Nogueira JM, Barreto MDC (2012) Anti-acetylcholinesterase and antioxidant activity of essential oils from Hedychium gardnerianum Sheppard ex Ker-Gawl. Molecules 17:3082–3092

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  78. Medeiros JR, Campos LB, Mendonça SC, Davin LB, Lewis NG (2003) Composition and antimicrobial activity of the essential oils from invasive species of the Azores, Hedychium gardnerianum and Pittosporum undulatum. Phytochemistry 64:561–565

    Article  CAS  PubMed  Google Scholar 

  79. Preethi PJ (2013) Herbal medicine for diabetes mellitus: a review. Int J Phytopharm 3:1–22

    Google Scholar 

  80. Dias CM, Madruga JS, Vouzela CFM, Borba AES (2021) Effect of sodium hydroxide treatment in ginger lily forage (Hedychium gardnerianum, Sheppard ex Ker-Gawl) as forage for animal feeding. Afr J Agric Res 17:268–272

    Article  CAS  Google Scholar 

  81. Macedo JF (1997) The genus Hedychium Koening (Zingiberaceae) in Minas Gerais State, Daphne. Rev Herbário PAMG da EPAMIG 7:27–31

    Google Scholar 

  82. Tripathi AK, Rao SM, Singh D, Chakravarty RB, Bhakuni DS (1987) Antifeedant activity of plant extracts against Spilosoma obliqua Walker. Curr Sci 56:607–609

    Google Scholar 

  83. AlShebly MM, AlQahtani FS, Govindarajan M, Gopinath K, Vijayan P, Benelli G (2017) Toxicity of ar-curcumene and epi-β-bisabolol from Hedychium larsenii (Zingiberaceae) essential oil on malaria, chikungunya and St. Louis encephalitis mosquito vectors. Ecotoxicol Environ Saf 137:149–157

    Article  CAS  PubMed  Google Scholar 

  84. Sirirugsa P (1999) Thai Zingiberaceae: species diversity and their uses. Pure Appl Chem 70:1–8

    Google Scholar 

  85. Mohammad NS, Milow P, Ong HC (2012) Traditional medicinal plants used by the Kensiu tribe of Lubuk Ulu Legong, Kedah, Malaysia. Stud Ethno-Med 6:149–153

    Article  Google Scholar 

  86. Jasril MLY, Ali AM, Sukari MA, Rahman AA, Othman AG, Kikuzaki H, Nakatani N (2003) Antioxidant and antitumor promoting activities of the flavonoids from Hedychium thyrsiforme. Pharm Biol 41:506–511

    Article  CAS  Google Scholar 

  87. Abdo MY, Ahmad WYW, Din LB, Ibrahim N (2015a) Chemical composition and antioxidant activity of Hedychium malayanum essential oils. Malays J Anal Sci 19:194–201

    Google Scholar 

  88. Singh OI, Devi AB (2020) Comparison of Antiurolithiatic Property of Orthosiphon spiralis, Hedychium marginatum, Thunbergia alata and Cystone: A Herbal Drug. Int J Health Sci Res, 10:82–87.

    Google Scholar 

  89. Devi KN, Sarma HN, Kumar S (2008) Estimation of essential and trace elements in some medicinal plants by PIXE and PIGE techniques. In: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 266, 1605-1610. https://doi.org/10.1016/j.nimb.2007.12.004.

  90. Thomas S, Mani B (2017) Composition, antibacterial and anti-oxidant potentials of the essential oil of Hedychium matthewii. Bangladesh J Pharmacol 12:173–179

    Article  Google Scholar 

  91. Suksathan R, Puangpradab R, Saratan N, Boonvun D (2016) Bioactive compounds and antioxidant properties of four Hedychium flowers for flavoured tea. In: VIII international postharvest symposium: enhancing supply chain and consumer benefits-ethical and technological issues, vol 1194, pp 1053–1056

    Google Scholar 

  92. Mohagan AB, Mendez NP (2019) Taxonomy, Recollection and Conservation of newly discovered populations of Hedychium philippinense (Zingiberaceae): an endemic and threatened species in The Philippines. Asian J Conserv Biol 8:88–92

    Google Scholar 

  93. Panyadee P, Muangyen N, Pongamornkul W, Inta A (2021) Food from forest: diversity of wild vegetables used by pwo people Thailand, ethnobiology of mountain communities in Asia. Springer, Cham, pp 47–69

    Google Scholar 

  94. Sabulal B, George V, Dan M, Pradeep NS (2007) Chemical composition and antimicrobial activities of the essential oils from the rhizomes of four Hedychium species from South India. J Essent Oil Res 19:93–97

    Article  CAS  Google Scholar 

  95. Xiao P, Sun C, Zahid M, Ishrud O, Pan Y (2001) New diterpene from Hedychium villosum. Fitoterapia 72:837–838

    Article  CAS  PubMed  Google Scholar 

  96. Singh B, Borthakur SK (2011) Wild medicinal plants used by tribal communities of Meghalaya. J Econ Taxon Bot 35:331–339

    Google Scholar 

  97. Zhu WM, Zhao Q, Li SL, Hao XJ (2007) Sesquiterpenoids from Hedychium yunnanense and Porana discifera, and the structural revision of two sesquiterpenoids from Laggera pterodonta. J Asian Nat Prod Res 9:277–283

    Article  CAS  PubMed  Google Scholar 

  98. Liu XH, Zhao DB, Yang CR, Wang HQ (2000) New sesquiterpenoids from Hedychium yunnanense gagnep. Chin Chem Lett 11:1009–1012

    CAS  Google Scholar 

  99. Li Y, Zhao S, Zeng G, Xu J, Li Y, Tan N (2016b) A New Sesquiterpene from the Rhizomes of Hedychium yunnanense. Chem Nat Compd 52:1026–1028

    Article  CAS  Google Scholar 

  100. Bottini AT, Garfagnoli DJ, Delgado LS, Dev V, Duong ST, Kelley CG, Keyer R, Raffel R, Joshi P, Mathela CS (1987) Sesquiterpene alcohols from Hedychium spicatum var. acuminatum. J Nat Prod 4:732–734

    Article  Google Scholar 

  101. Pant AK, Mathela CS, Dev V, Bottini AT (1992) Rhizome essential oil of Hedychium aurantiacum (Zingiberaceae), a potential source of (+)-linalool. J Essent Oil Res 4(2):129–131

    Article  CAS  Google Scholar 

  102. Mohammadhosseini M (2015) Chemical composition of the volatile fractions from flowers, leaves and stems of Salvia mirzayanii by HS-SPME-GC-MS. J Essent Oil Bear Pl 18:464–476

    Article  CAS  Google Scholar 

  103. Venditti A, Frezza C, Bianco A, Serafini M, Cianfaglione K, Nagy DU, Iannarelli R, Caprioli G, Maggi F (2017) Polar constituents, essential oil and antioxidant activity of marsh woundwort. Chem Biodivers 14:e1600401

    Article  Google Scholar 

  104. Mohammadhosseini M, Akbarzadeh A, Hashemi-Moghaddam H, Nafchi AM, Mashayekhi HA, Aryanpour A (2016) Chemical composition of the essential oils from the aerial parts of Artemisia sieberi by using conventional hydrodistillation and microwave assisted hydrodistillation: A comparative study. J Essent Oil Bear Pl 19:32–45

    Article  CAS  Google Scholar 

  105. Lechat-Vahirua I, François P, Menut C, Lamaty G, Bessiere JM (1993) Aromatic plants of French Polynesia. I. Constituents of the essential oils of rhizomes of three Zingiberaceae: Zingiber zerumbet Smith, Hedychium coronarium Koeing and Etlingera cevuga Smith. J Essent Oil Res 5:55–59

    Article  CAS  Google Scholar 

  106. Joy B, Rajan A, Abraham E (2007) Antimicrobial activity and chemical composition of essential oil from Hedychium coronarium. Phytother Res 21:439–443

    Article  CAS  PubMed  Google Scholar 

  107. dos Santos BC, Barata LE, Marques FA, Baroni AC, Karnos BA, de Oliveira PR, Guerrero PG Jr (2010) Composition of leaf and rhizome essential oils of Hedychium coronarium Koen. from Brazil. J Essent Oil Res 22:305–306

    Article  Google Scholar 

  108. Van Thanh B, Dai DN, Thang TD, Binh NQ, Anh LDN, Ogunwande IA (2014) Composition of essential oils of four Hedychium species from Vietnam. Chem Cent J 8:1–5

    Google Scholar 

  109. Ray A, Dash B, Sahoo S, Sahoo A, Jena S, Kar B, Chatterjee T, Ghosh B, Nayak S (2017b) Development and validation of an HPTLC method for estimation of coronarin D in Hedychium coronarium rhizome. Acta Chromatogr 29:415–426

    Article  CAS  Google Scholar 

  110. Costa RO, Jose CM, Grombone-Guaratini MT, Matos DMS (2019) Chemical characterization and phytotoxicity of the essential oil from the invasive Hedychium coronarium on seeds of Brazilian riparian trees. Flora 257:151411

    Article  Google Scholar 

  111. Ahmad FB, Jantan IB, Jalil J (2004) Constituents of the rhizome oil of Hedychium cylindricum Ridl. J Essent Oil Res 16:299–301

    Article  Google Scholar 

  112. Moellenbeck S, König T, Schreier P, Schwab W, Rajaonarivony J, Ranarivelo L (1997) Chemical composition and analyses of enantiomers of essential oils from Madagascar. Flavour Fragr J 12:63–69

    Article  CAS  Google Scholar 

  113. Ray A, Dash B, Sahoo A, Nasim N, Panda PC, Patnaik J, Ghosh B, Nayak S, Kar B (2017a) Assessment of the terpenic composition of Hedychium coronarium oil from Eastern India. Ind Crop Prod 97:49–55

    Article  CAS  Google Scholar 

  114. Abdo MY, Ahmad WYW, Din LB, Ibrahim N (2015b) Composition of Hedychium malayanum rhizome essential oil and its antioxidant activity. Malays J Anal Sci 19:1147–1155

    Google Scholar 

  115. Verma RS, Padalia RC (2010) Comparative essential oil composition of different vegetative parts of Hedychium spicatum Smith. from Uttarakhand, India. Int J Green Pharm 4(4):292

    Article  Google Scholar 

  116. Weyerstahl P, Marschall H, Schneider S, Subba GC (1995) Constituents of the essential oil from the rhizomes of Hedychium acumnatum Roscoe. Flavour Fragr J 10:179–185

    Article  CAS  Google Scholar 

  117. Gurib-Fakim A, Maudarbaccus N, Leach D, Doimo L, Wohlmuth H (2002) Essential oil composition of Zingiberaceae species from Mauritius. J Essent Oil Res 14:271–273

    Article  CAS  Google Scholar 

  118. Lu Y, Zhong CX, Wang L, Lu C, Li XL, Wang PJ (2009) Anti-inflammation activity and chemical composition of flower essential oil from Hedychium coronarium. Afr J Biotechnol 8: 5373–5377.

    Google Scholar 

  119. Ray A, Jena S, Dash B, Kar B, Halder T, Chatterjee T, Ghosh B, Panda PC, Nayak S, Mahapatra N (2018) Chemical diversity, antioxidant and antimicrobial activities of the essential oils from Indian populations of Hedychium coronarium Koen. Ind Crop Prod 112:353–362

    Article  CAS  Google Scholar 

  120. Abdo MY, Ahmad WYW (2017) Phytochemical study of Hedychium malayanum (Zingiberaceae). Sains Malays 46:83–89

    Article  CAS  Google Scholar 

  121. Benjamin S, Preethi TP, Shinija K, Takhi KP, Sabu M (2009) Micropropagation and chemical profiling of Alpinia malaccensis and Hedychium coccineum. J Trop Med Plants 10:95–99

    Google Scholar 

  122. Hartati RIKA, Suganda AG, Fidrianny IRDA (2015) Chemical composition and antimicrobial activity of diterpene and essential oils of Hedychium roxburghii Blume rhizome. Asian J Pharm Clin Res 8:209–214

    Google Scholar 

  123. Raj G, Dan M, George V, Sethuraman MG (2013) Studies on chemical composition of essential oils from leaf and inflorescence of Hedychium larsenii M. Dan and Sathish. J Essent Oil Res 25:33–38

    Article  CAS  Google Scholar 

  124. Arya S, Kumar R, Prakash O, Kumar S, Mahawer SK, Chamoli S, Kumar P, Srivastava RM, de Oliveira MS (2022) Chemical composition and biological activities of Hedychium coccineum Buch.-Ham. ex Sm. essential oils from Kumaun hills of Uttarakhand. Molecules 27(15):4833

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  125. Kumar R, Prakash O, Singh SP, Pant AK, Isidorov V, Szczepaniak L (2017) Chemical composition, antioxidant and myorelaxant activity of essential oil of Hedychium aurantiacum. Asian J Chem 29:2587–2591

    Article  CAS  Google Scholar 

  126. Báez D, Pino JA, Morales D (2011) Floral scent composition in Hedychium coronarium J. Koenig analyzed by SPME. J Essent Oil Res 23:64–67

    Article  Google Scholar 

  127. Zhi N (2006) Chemical constituents of the volatile oil from the rhizome of Hedychium forrestii Diels. J Trop Subtrop Bot 14:417–420

    Google Scholar 

  128. Koundal R, Rawat K, Agnihotri VK, Meena RL, Gopichand SRD, Padwad YS (2015) Temporal and spatial variation in quality of essential oil of Hedychium spicatum and evaluation of its antioxidant activity. J Essent Oil Res 27:217–224

    Article  CAS  Google Scholar 

  129. Raina AP, Negi KS (2015) Essential oil composition of Hedychium spicatum Buch.-Ham. ex Smith. from Uttarakhand, India. J Essent Oil Bear Pl 18:382–388

    Article  CAS  Google Scholar 

  130. Gopichand RL, Maurya AK, Agnihotri VK, Singh RD (2017) Effect of growth hormones on seed germination and plant growth: with chemical components of Hedychium spicatum Ham. ex. Smith. Ornam Med Plants 1:1–14

    Google Scholar 

  131. Kalagatur NK, Kamasani JR, Siddaiah C, Gupta VK, Krishna K, Mudili V (2018) Combinational inhibitory action of Hedychium spicatum L. essential oil and γ-radiation on growth rate and mycotoxins content of Fusarium graminearum in maize: response surface methodology. Front Microbiol 9:1511

    Article  PubMed  PubMed Central  Google Scholar 

  132. Rawat A, Rawat M, Prakash O, Kumar R, Punetha H, Rawat DS (2022) Comparative study on eucalyptol and camphor rich essential oils from rhizomes of Hedychium spicatum Sm. and their pharmacological, antioxidant and antifungal activities. An Acad Bras Ciênc 94:e20210932

    Article  CAS  PubMed  Google Scholar 

  133. Xie XY, Shi XB, Xu JJ, He CG, Yang SC (2012) Determination of volatile oil of Hedychium yunnanense Gagnep. by gas chromatography-mass spectrography. J Yunnan Agric Univ Nat Sci 4: 607–610.

    Google Scholar 

  134. Chimnoi N, Pisutjaroenpong S, Ngiwsara L, Dechtrirut D, Chokchaichamnankit D, Khunnawutmanotham N, Mahidol C, Techasakul S (2008) Labdane diterpenes from the rhizomes of Hedychium coronarium. Nat Prod Res 22:1249–1256

    Article  CAS  PubMed  Google Scholar 

  135. Chimnoi N, Sarasuk C, Khunnawutmanotham N, Intachote P, Seangsai S, Saimanee B, Pisutjaroenpong S, Mahidol C, Techasakul S (2009) Phytochemical reinvestigation of labdane-type diterpenes and their cytotoxicity from the rhizomes of Hedychium coronarium. Phytochem Lett 2:184–187

    Article  CAS  Google Scholar 

  136. Suresh G, Reddy PP, Babu KS, Shaik TB, Kalivendi SV (2010) Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium. Bioorg Med Chem Lett 20:7544–7548

    Article  CAS  PubMed  Google Scholar 

  137. Kumrit I, Suksamrarn A, Meepawpan P, Songsri S, Nuntawong N (2010) Labdane-type diterpenes from Hedychium gardnerianum with potent cytotoxicity against human small cell lung cancer cells. Phytother Res 24:1009–1013

    Article  CAS  PubMed  Google Scholar 

  138. Zhao Q, Zou C, Yu Q, Zhao SD, He HP, Hao XJ (2012) Cytotoxic labdane-type diterpenes and diterpene derivative from Hedychium villosum [J]. Chem J Chin Univ 33(6):1220

    CAS  Google Scholar 

  139. Zhao H, Zeng G, Zgphao S, Xu J, Kong L, Li Y, Tan N, Yang S (2015) Cytotoxic labdane-type diterpenes from Hedychium longipetalum inhibiting production of nitric oxide. Bioorg Med Chem Lett 25:4572–4575

    Article  CAS  PubMed  Google Scholar 

  140. Qing Z, Xiao-qiong HE, Xiao-Jiang HAO, Cheng Z (2010) Anticancer effect of diterpenes from Hedychium yunnanense. Nat Prod Res Dev 22:395

    Google Scholar 

  141. Suresh G, Poornima B, Babu KS, Yadav PA, Rao MSA, Siva B, Prasad KR, Nayak VL, Ramakrishna S (2013) Cytotoxic sesquiterpenes from Hedychium spicatum: Isolation, structure elucidation and structure-activity relationship studies. Fitoterapia 86:100–107

    Article  CAS  PubMed  Google Scholar 

  142. Chen JJ, Wu YC, Ding JW, Chen JF (2010) New labdane-type diterpenes and antitubercular constituents from Hedychium coronarium. Planta Med 76:222

    Article  Google Scholar 

  143. Phukerd U, Soonwera M (2013) Larvicidal and pupicidal activities of essential oils from Zingiberaceae plants against Aedes aegypti (Linn.) and Culex quinquefasciatus Say mosquitoes. Southeast Asian J Trop Med Public Health 44:761–771

    PubMed  Google Scholar 

  144. Van Kiem P, Anh HLT, Nhiem NX, Van Minh C, Thuy NTK, Yen PH, Hang DT, Tai BH, Mathema VB, Koh YS, Kim YH (2012) Labdane-type diterpenoids from the rhizomes of Hedychium coronarium inhibit lipopolysaccharide-stimulated production of pro-inflammatory cytokines in bone marrow-derived dendritic cells. Chem Pharm Bull 60:246–250

    Article  CAS  Google Scholar 

  145. Zhan ZJ, Wen YT, Ren FY, Rao GW, Shan WG, Li CP (2012) Diterpenoids and a Diarylheptanoid from Hedychium coronarium with significant anti-angiogenic and cytotoxic activities. Chem Biodivers 9:2754–2760

    Article  CAS  PubMed  Google Scholar 

  146. Chen JJ, Ting CW, Wu YC, Hwang TL, Cheng MJ, Sung PJ, Wang TC, Chen JF (2013) New labdane-type diterpenoids and anti-inflammatory constituents from Hedychium coronarium. Int J Mol Sci 14:13063–13077

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Uttarakhand, India

    Avneesh Rawat, Om Prakash, Ravendra Kumar & Sushila Arya

  2. Department of Biological Sciences, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Uttarakhand, India

    D. S. Rawat

  3. Department of Plant Pathology, College of Agriculture, G.B. Pant University of Agriculture and Technology, U.S. Nagar, Uttarakhand, India

    Satya Kumar

Authors
  1. Avneesh Rawat
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Om Prakash
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ravendra Kumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Sushila Arya
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. D. S. Rawat
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Satya Kumar
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Hosakatte Niranjana Murthy

  2. Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju, Korea (Republic of)

    Kee Yoeup Paek

  3. Dept of Horticultural Science, Chungbuk National University, Cheongju, Korea (Republic of)

    So-Young Park

Rights and permissions

Reprints and permissions

Copyright information

© 2023 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Rawat, A., Prakash, O., Kumar, R., Arya, S., Rawat, D.S., Kumar, S. (2023). Bioactive Compounds and Biological Activities of Hedychium Species. In: Murthy, H.N., Paek, K.Y., Park, SY. (eds) Bioactive Compounds in the Storage Organs of Plants. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-031-29006-0_29-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-29006-0_29-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-29006-0

  • Online ISBN: 978-3-031-29006-0

  • eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics

Publish with us

Policies and ethics

Search

Navigation