Abstract
As for other patients with hematological malignancies, both short- and long-term survival of critically ill allogeneic hematopoietic stem cell transplantation (Allo-HSCT) patients have improved significantly in the last decades. Although intensive care unit (ICU) admission remains clearly associated with poor outcomes in Allo-HSCT recipients, long-term survival is now comparable between ICU survivors and patients never admitted to the ICU. This finding is probably the strongest argument to maintain the doors of ICU widely opened to critically ill Allo-HSCT recipients. The goals of care should be defined at ICU admission for every Allo-HSCT recipient, requiring a close collaboration between intensivists and hematologists in order to assess primary disease status, number of organ failures, acute graft-versus-host disease (aGVHD) trajectory, and patient expectations.
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Lafarge, A., Azoulay, E. (2023). Outcomes in Critically Ill Allogeneic Hematopoietic Stem Cell Transplantation Recipients. In: Soubani, A.O. (eds) Pulmonary and Critical Care Considerations of Hematopoietic Stem Cell Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-031-28797-8_24
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DOI: https://doi.org/10.1007/978-3-031-28797-8_24
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