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Physiology of the Nose and Paranasal Sinuses: Mucociliary Clearance

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Contemporary Rhinology: Science and Practice

Abstract

Normal mucociliary clearance (MCC) is essential for the maintenance of an effective primary defence mechanism against inhaled respiratory pathogens, allergens and pollutants. Respiratory cilia and mucus are vital components of the mucociliary apparatus and various conditions, and diseases can affect proper function. Testing of the mucociliary clearance will also be addressed.

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Acknowledgements

Medical drawings are reproduced with permission from Sannia Sjostedt, MD, PhD. Video materials are provided with permission from Professor Jann Mortensen, MD, DMSc.

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Correspondence to Christian von Buchwald .

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Electronic Supplementary Material

502999_1_En_4_MOESM1_ESM.mp4

Normal ciliary beating using high-speed video microscopy (AVI 6092 kb)

Normal nasal mucociliary clearance visualized using technetium-99 scintigraphy (AVI 919 kb)

Immotile cilia in a patient with primary ciliary dyskinesia evaluated with high-speed video microscopy (AVI 693 kb)

Video 4.1

Normal ciliary beating using high-speed video microscopy (AVI 6092 kb)

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Alanin, M.C., von Buchwald, C. (2023). Physiology of the Nose and Paranasal Sinuses: Mucociliary Clearance. In: Swift, A.C., Carrie, S., de Souza, C. (eds) Contemporary Rhinology: Science and Practice. Springer, Cham. https://doi.org/10.1007/978-3-031-28690-2_4

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  • DOI: https://doi.org/10.1007/978-3-031-28690-2_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-28689-6

  • Online ISBN: 978-3-031-28690-2

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