Abstract
Head and neck (H &N) cancer is one of the most prevalent cancers [1]. In its treatment and prognosis analysis, tumors and metastatic lymph nodes may play an important role but their manual segmentations are time-consuming and laborious. In this paper, we propose a coarse-to-fine ensembling framework to segment the H &N tumor and metastatic lymph nodes automatically from Positron Emission Tomography (PET) and Computed Tomography (CT) images. The framework consists of three steps. The first step is to locate the head region in CT images. The second step is a coarse segmentation, to locate the tumor and lymph region of interest (ROI) from the head region. The last step is a fine segmentation, to get the final precise predictions of tumors and metastatic lymph nodes, where we proposed a ensembling refinement model. This framework is evaluated quantitatively with aggregated Dice Similarity Coefficient (DSC) of 0.77782 in the task 1 of the HECKTOR 2022 challenge[2, 3] as team SJTU426.
Supported by Shanghai Jiao Tong University.
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References
Parkin, D.M., Bray, F., Ferlay, J., Pisani, P.: Global cancer statistics. CA Cancer J. Clin. 55(2), 74–108 (2005)
Oreiller, V., et al.: Head and neck tumor segmentation in PET/CT: the HECKTOR challenge. Med. Image Anal. 77, 102336 (2022)
Andrearczyk, V., et al.: Overview of the HECKTOR challenge at MICCAI 2022: automatic head and neck tumor segmentation and outcome prediction in PET/CT. In: Head and Neck Tumor Segmentation and Outcome Prediction (2021). Springer, Heidelberg. https://doi.org/10.1007/978-3-030-98253-9_1
Gillies, R.J., Kinahan, P.E., Hricak, H.: Radiomics: images are more than pictures, they are data. Radiology 278(2), 563–577 (2016)
Vallieres, M., et al.: Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer. Sci. Rep. 7(1), 1–14 (2017)
Bogowicz, M., et al.: Comparison of PET and CT radiomics for prediction of local tumor control in head and neck squamous cell carcinoma. Acta Oncologica 56(11), 1531–1536 (2017)
Vaswani, A., et al.: Attention is all you need. Adv. Neural Inf. Process. Syst. 30 (2017)
Xie, J., Peng, Y.: The head and neck tumor segmentation based on 3D U-Net. In: 3D Head and Neck Tumor Segmentation in PET/CT Challenge, pp. 92–98. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-98253-9_8
An, C., Chen, H., Wang, L.: A coarse-to-fine framework for head and neck tumor segmentation in CT and PET images. In: 3D Head and Neck Tumor Segmentation in PET/CT Challenge, pp. 50–57. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-98253-9_3
Isensee, F., Jaeger, P.F., Kohl, S.A., Petersen, J., Maier-Hein, K.H.: nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nat. Methods 18(2), 203–211 (2021)
Iantsen, A., Visvikis, D., Hatt, M.: Squeeze-and-excitation normalization for automated delineation of head and neck primary tumors in combined PET and CT images. In: Andrearczyk, V., Oreiller, V., Depeursinge, A. (eds.) HECKTOR 2020. LNCS, vol. 12603, pp. 37–43. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-67194-5_4
Zhou, H.Y., Guo, J., Zhang, Y., Yu, L., Wang, L., Yu, Y.: nnformer: interleaved transformer for volumetric segmentation (2021). arXiv preprint arXiv:2109.03201
He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)
Kumar, N., Verma, R., Sharma, S., Bhargava, S., Vahadane, A., Sethi, A.: A dataset and a technique for generalized nuclear segmentation for computational pathology. IEEE Trans. Med. Imaging 36(7), 1550–1560 (2017)
Krizhevsky, A., Sutskever, I., Hinton, G.E.: Imagenet classification with deep convolutional neural networks. Commun. ACM 60(6), 84–90 (2017)
Loshchilov, I., Hutter, F.: SGDR: stochastic gradient descent with warm restarts. arXiv preprint arXiv:1608.03983 (2016)
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Sun, X., An, C., Wang, L. (2023). A Coarse-to-Fine Ensembling Framework for Head and Neck Tumor and Lymph Segmentation in CT and PET Images. In: Andrearczyk, V., Oreiller, V., Hatt, M., Depeursinge, A. (eds) Head and Neck Tumor Segmentation and Outcome Prediction. HECKTOR 2022. Lecture Notes in Computer Science, vol 13626. Springer, Cham. https://doi.org/10.1007/978-3-031-27420-6_3
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