Skip to main content

A Coarse-to-Fine Ensembling Framework for Head and Neck Tumor and Lymph Segmentation in CT and PET Images

  • Conference paper
  • First Online:
Head and Neck Tumor Segmentation and Outcome Prediction (HECKTOR 2022)

Abstract

Head and neck (H &N) cancer is one of the most prevalent cancers [1]. In its treatment and prognosis analysis, tumors and metastatic lymph nodes may play an important role but their manual segmentations are time-consuming and laborious. In this paper, we propose a coarse-to-fine ensembling framework to segment the H &N tumor and metastatic lymph nodes automatically from Positron Emission Tomography (PET) and Computed Tomography (CT) images. The framework consists of three steps. The first step is to locate the head region in CT images. The second step is a coarse segmentation, to locate the tumor and lymph region of interest (ROI) from the head region. The last step is a fine segmentation, to get the final precise predictions of tumors and metastatic lymph nodes, where we proposed a ensembling refinement model. This framework is evaluated quantitatively with aggregated Dice Similarity Coefficient (DSC) of 0.77782 in the task 1 of the HECKTOR 2022 challenge[2, 3] as team SJTU426.

Supported by Shanghai Jiao Tong University.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Parkin, D.M., Bray, F., Ferlay, J., Pisani, P.: Global cancer statistics. CA Cancer J. Clin. 55(2), 74–108 (2005)

    Article  Google Scholar 

  2. Oreiller, V., et al.: Head and neck tumor segmentation in PET/CT: the HECKTOR challenge. Med. Image Anal. 77, 102336 (2022)

    Article  Google Scholar 

  3. Andrearczyk, V., et al.: Overview of the HECKTOR challenge at MICCAI 2022: automatic head and neck tumor segmentation and outcome prediction in PET/CT. In: Head and Neck Tumor Segmentation and Outcome Prediction (2021). Springer, Heidelberg. https://doi.org/10.1007/978-3-030-98253-9_1

  4. Gillies, R.J., Kinahan, P.E., Hricak, H.: Radiomics: images are more than pictures, they are data. Radiology 278(2), 563–577 (2016)

    Article  Google Scholar 

  5. Vallieres, M., et al.: Radiomics strategies for risk assessment of tumour failure in head-and-neck cancer. Sci. Rep. 7(1), 1–14 (2017)

    Article  Google Scholar 

  6. Bogowicz, M., et al.: Comparison of PET and CT radiomics for prediction of local tumor control in head and neck squamous cell carcinoma. Acta Oncologica 56(11), 1531–1536 (2017)

    Article  Google Scholar 

  7. Vaswani, A., et al.: Attention is all you need. Adv. Neural Inf. Process. Syst. 30 (2017)

    Google Scholar 

  8. Xie, J., Peng, Y.: The head and neck tumor segmentation based on 3D U-Net. In: 3D Head and Neck Tumor Segmentation in PET/CT Challenge, pp. 92–98. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-98253-9_8

  9. An, C., Chen, H., Wang, L.: A coarse-to-fine framework for head and neck tumor segmentation in CT and PET images. In: 3D Head and Neck Tumor Segmentation in PET/CT Challenge, pp. 50–57. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-98253-9_3

  10. Isensee, F., Jaeger, P.F., Kohl, S.A., Petersen, J., Maier-Hein, K.H.: nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nat. Methods 18(2), 203–211 (2021)

    Article  Google Scholar 

  11. Iantsen, A., Visvikis, D., Hatt, M.: Squeeze-and-excitation normalization for automated delineation of head and neck primary tumors in combined PET and CT images. In: Andrearczyk, V., Oreiller, V., Depeursinge, A. (eds.) HECKTOR 2020. LNCS, vol. 12603, pp. 37–43. Springer, Cham (2021). https://doi.org/10.1007/978-3-030-67194-5_4

    Chapter  Google Scholar 

  12. Zhou, H.Y., Guo, J., Zhang, Y., Yu, L., Wang, L., Yu, Y.: nnformer: interleaved transformer for volumetric segmentation (2021). arXiv preprint arXiv:2109.03201

  13. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

  14. Kumar, N., Verma, R., Sharma, S., Bhargava, S., Vahadane, A., Sethi, A.: A dataset and a technique for generalized nuclear segmentation for computational pathology. IEEE Trans. Med. Imaging 36(7), 1550–1560 (2017)

    Article  Google Scholar 

  15. Krizhevsky, A., Sutskever, I., Hinton, G.E.: Imagenet classification with deep convolutional neural networks. Commun. ACM 60(6), 84–90 (2017)

    Article  Google Scholar 

  16. Loshchilov, I., Hutter, F.: SGDR: stochastic gradient descent with warm restarts. arXiv preprint arXiv:1608.03983 (2016)

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lisheng Wang .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Sun, X., An, C., Wang, L. (2023). A Coarse-to-Fine Ensembling Framework for Head and Neck Tumor and Lymph Segmentation in CT and PET Images. In: Andrearczyk, V., Oreiller, V., Hatt, M., Depeursinge, A. (eds) Head and Neck Tumor Segmentation and Outcome Prediction. HECKTOR 2022. Lecture Notes in Computer Science, vol 13626. Springer, Cham. https://doi.org/10.1007/978-3-031-27420-6_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-27420-6_3

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-27419-0

  • Online ISBN: 978-3-031-27420-6

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics