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Advanced Functional Echocardiographic Views Including PDA Assessment and Hemodynamic Evaluation

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Point-of-Care Ultrasound for the Neonatal and Pediatric Intensivist

Abstract

A bedside point-of-care echocardiography can provide real-time anatomical, physiological, and hemodynamic information which helps in making physiology-based timely and accurate clinical decisions. Application of advanced echocardiography techniques can be applied to assess cardiac function, preload and afterload, and evaluate cardiac contractility/functions. They can be applied to estimate cardiac output and in diagnosis and hemodynamic evaluation of pulmonary hypertension and patent ductus arteriosus. It is indispensable in the management of patients with shock, pulmonary hypertension, and patent ductus arteriosus. While most of these conditions have been described in the other chapters of this book, this chapter focuses on (1) diagnosis and hemodynamic evaluation of patent ductus arteriosus, and (2) Estimation of left ventricle output, right ventricle output, and superior vena cava flow. Ductal patency cases can be assessed on point-of-care ultrasound (POCUS), however a detailed hemodynamic evaluation is out of the scope of POCUS assessment, and it should be performed by a pediatric cardiologist or neonatologist trained in echocardiography. Although hemodynamic evaluation of the patent ductus arteriosus, estimation of left and right cardiac outputs, and superior vena cava flow are out of the scope of cardiac POCUS, a brief description of these echocardiographic techniques have been provided in this chapter to enhance the understanding of cardiovascular physiology for the readers who are interested in learning advanced echocardiography. 

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References

  1. Singh Y. Echocardiographic evaluation of Hemodynamics in neonates and children. Front Pediatr. 2017;5:201. https://doi.org/10.3389/fped.2017.00201.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Singh Y, Fraisse A, Erdeve O, Atasay B. Echocardiographic diagnosis and hemodynamic evaluation of patent ductus arteriosus in extremely low gestational age newborn (ELGAN) infants. Front Pediatr. 2020;8:573627. https://doi.org/10.3389/fped.2020.573627.

    Article  PubMed  PubMed Central  Google Scholar 

  3. McNamara PJ, Sehgal A. Towards rational management of the patent ductus arteriosus: the need for disease staging. Arch Dis Child Fetal Neonatal Ed. 2007;92:F424–7. https://doi.org/10.1136/adc.2007.118117.

    Article  PubMed  PubMed Central  Google Scholar 

  4. van Laere D, van Overmeire B, Gupta S, El Khuffash A, Savoia M, McNamara PJ, et al. Application of NPE in the assessment of a patent ductus arteriosus. Pediatr Res. 2018;84:S46–56. https://doi.org/10.1038/s41390-018-0077-x.

    Article  Google Scholar 

  5. Fraisse A, Bautista C, Burmester M, Lane M, Singh Y. Transcatheter closure of patent ductus arteriosus in infants with weight under 1,500 grams. Front Pediatr. 2020;8:558256.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Singh Y, Tissot C. Echocardiographic evaluation of transitional circulation for the neonatologists. TINEC research article. Front Pediatr. 2018;6:79. https://doi.org/10.3389/fped.2018.00140.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Condo M, Evans N, Bellu R, Kluckow M. Echocardiographic assessment of ductal significance: retrospective comparison of two methods. Arch Dis Child Fetal Neonatal Ed. 2012;97:F35–8. https://doi.org/10.1136/adc.2010.207233.

    Article  PubMed  Google Scholar 

  8. Smith A, Maguire M, Livingstone V, Dempsey EM. Peak systolic to end diastolic flow velocity ratio is associated with ductal patency in infants below 32 weeks of gestation. Arch Dis Child Fetal Neonatal Ed. 2015;100:F132–6. https://doi.org/10.1136/archdischild-2014-306439.

    Article  CAS  PubMed  Google Scholar 

  9. El Hajjar M, Vaksmann G, Rakza T, Kongolo G, Storme L. Severity of the ductal shunt: a comparison of different markers. Arch Dis Child Fetal Neonatal Ed. 2005;90:F419–22. https://doi.org/10.1136/adc.2003.027698.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Iyer P, Evans N. Re-evaluation of the left atrial to aortic root ratio as a marker of patent ductus arteriosus. Arch Dis Child Fetal Neonatal Ed. 1994;70:F112–7. https://doi.org/10.1136/fn.70.2.F112.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Singh Y, Katheria A, Tissot C. Functional echocardiography in the neonatal intensive care unit. Indian Pediatr. 2018;14:417–25. https://doi.org/10.1007/s13312-018-1286-4.

    Article  Google Scholar 

  12. Abushaban L, Vel MT, Rathinasamy J, Sharma P. Normal reference ranges for left ventricular dimensions in preterm infants. Ann Pediatr Cardiol. 2014;7:180–6. https://doi.org/10.4103/0974-2069.140832.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Kheiwa A, Ross RD, Kobayashi D. Reversal of severe mitral regurgitation by device closure of a large patent ductus arteriosus in a premature infant. Cardiol Young. 2017;27:189–92. https://doi.org/10.1017/S1047951116000998.

    Article  PubMed  Google Scholar 

  14. Walther FJ, Kim DH, Ebrahimi M, Siassi B. Pulsed Doppler measurement of left ventricular output as early predictor of symptomatic patent ductus arteriosus in very preterm infants. Biol Neonate. 1989;56:121–8. https://doi.org/10.1159/000243112.

    Article  CAS  PubMed  Google Scholar 

  15. Lee A, Liestøl K, Nestaas E, Brunvand L, Lindemann R, Fugelseth D. Superior vena cava flow: feasibility and reliability of the off-line analyses. Arch Dis Child Fetal Neonatal Ed. 2010;95:F121–5. https://doi.org/10.1136/adc.2009.176883.

    Article  CAS  PubMed  Google Scholar 

  16. Mertens L, Seri I, Marek J, Arlettaz R, Barker P, McNamara P, et al. Targeted neonatal echocardiography in the neonatal intensive care unit: practice guidelines and recommendations for training. Writing Group of the American Society of Echocardiography (ASE) in collaboration with the European Association of Echocardiography (EAE) and the Association for European Pediatric Cardiologists (AEPC). J Am Soc Echocardiogr. 2011;24:1057–78. https://doi.org/10.1016/j.echo.2011.07.014.

    Article  PubMed  Google Scholar 

  17. Broadhouse KM, Price AN, Durighel G, Cox DJ, Finnemore AE, Edwards AD, et al. Assessment of PDA shunt and systemic blood flow in newborns using cardiac MRI. NMR Biomed. 2013;26:1135–41. https://doi.org/10.1002/nbm.2927.

    Article  PubMed  Google Scholar 

  18. Ecury-Goossen GM, Raets MMA, Camfferman FA, Vos RHJ, van Rosmalen J, Reiss IRM, et al. Resistive indices of cerebral arteries in very preterm infants: values throughout stay in the neonatal intensive care unit and impact of patent ductus arteriosus. Pediatr Radiol. 2016;46:1291–300. https://doi.org/10.1007/s00247-016-3615-x.

    Article  PubMed  PubMed Central  Google Scholar 

  19. El-Khuffash A, James AT, Corcoran JD, Dicker P, Franklin O, Elsayed YN, et al. A patent ductus arteriosus severity score predicts chronic lung disease or death before discharge. J Pediatr. 2015;167:1354–61. https://doi.org/10.1016/j.jpeds.2015.09.028.

    Article  PubMed  Google Scholar 

  20. Alverson DC, Eldridge M, Dillon T, Yabek SM, Berman W Jr. Noninvasive pulsed Doppler determination of cardiac output in neonates and children. J Pediatr. 1982;101:46–50.

    Article  CAS  PubMed  Google Scholar 

  21. Alverson DC. Neonatal cardiac output measurement using pulsed Doppler ultrasound. Clin Perinatol. 1985;12:101–27.

    Article  CAS  PubMed  Google Scholar 

  22. Ficial B, Finnemore AE, Cox DJ, Broadhouse KM, Price AN, Durighel G, et al. Validation study of the accuracy of echocardiographic measurements of systemic blood flow volume in newborn infants. J Am Soc Echocardiogr. 2013;26:1365–71.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Groves AM, Chiesa G, Durighel G, et al. Functional cardiac MRI in preterm and term newborns. Arch Dis Child Fetal Neonatal Ed. 2011;96:F86–91.

    Article  PubMed  Google Scholar 

  24. Osborn DA, Evans N, Kluckow M, Bowen JR, Rieger I. Low superior vena cava flow and effect of inotropes on neurodevelopment to 3 years in preterm infants. Pediatrics. 2007;120:372–80.

    Article  PubMed  Google Scholar 

  25. Miletin J, Dempsey EM. Low superior vena cava flow on day 1 and adverse outcome in the very low birthweight infant. Arch Dis Child Fetal Neonatal Ed. 2008;93:F368–71.

    Article  CAS  PubMed  Google Scholar 

  26. El-Khuffash AF, Jain A, Weisz D, Mertens L, McNamara PJ. Assessment and treatment of post patent ductus arteriosus ligation syndrome. J Pediatr. 2014;165:46–52.

    Article  CAS  PubMed  Google Scholar 

  27. Kluckow M, Evans N. Superior vena cava flow in newborn infants: a novel marker of systemic blood flow. Arch Dis Child Fetal Neonatal Ed. 2000;82:F182–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Groves AM, Kuschel CA, Knight DB, Skinner JR. Echocardiographic assessment of blood flow volume in the superior vena cava and descending aorta in the newborn infant. Arch Dis Child Fetal Neonatal Ed. 2008;93:F24–8.

    Article  CAS  PubMed  Google Scholar 

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Singh, Y., Joye, S., Tissot, C. (2023). Advanced Functional Echocardiographic Views Including PDA Assessment and Hemodynamic Evaluation. In: Singh, Y., Tissot, C., Fraga, M.V., Conlon, T. (eds) Point-of-Care Ultrasound for the Neonatal and Pediatric Intensivist. Springer, Cham. https://doi.org/10.1007/978-3-031-26538-9_8

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  • DOI: https://doi.org/10.1007/978-3-031-26538-9_8

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